UniProtKB - I3N9P3 (I3N9P3_ICTTR)
Protein
Submitted name:
Uncharacterized protein
Gene
ZBTB7A
Organism
Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
Status
Functioni
GO - Molecular functioni
- activating transcription factor binding Source: Ensembl
- androgen receptor binding Source: Ensembl
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: Ensembl
- histone acetyltransferase binding Source: Ensembl
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: Ensembl
- SMAD binding Source: Ensembl
- transcription corepressor binding Source: Ensembl
GO - Biological processi
- B cell differentiation Source: Ensembl
- chromatin remodeling Source: Ensembl
- double-strand break repair via classical nonhomologous end joining Source: Ensembl
- erythrocyte maturation Source: Ensembl
- fat cell differentiation Source: Ensembl
- negative regulation of androgen receptor signaling pathway Source: Ensembl
- negative regulation of Notch signaling pathway Source: Ensembl
- negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
- positive regulation of NF-kappaB transcription factor activity Source: Ensembl
- protein localization to nucleus Source: Ensembl
- regulation of alternative mRNA splicing, via spliceosome Source: Ensembl
- regulation of apoptotic process Source: Ensembl
- regulation of glycolytic process Source: Ensembl
- regulation of transcription regulatory region DNA binding Source: Ensembl
- transcription, DNA-templated Source: Ensembl
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:ZBTB7AImported |
Organismi | Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)Imported |
Taxonomic identifieri | 43179 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciuromorpha › Sciuridae › Xerinae › Marmotini › Ictidomys |
Proteomesi |
|
Subcellular locationi
Nucleus
- DNA-dependent protein kinase complex Source: Ensembl
- NuRD complex Source: Ensembl
Other locations
- cytoplasm Source: Ensembl
- site of double-strand break Source: Ensembl
Interactioni
GO - Molecular functioni
- activating transcription factor binding Source: Ensembl
- androgen receptor binding Source: Ensembl
- histone acetyltransferase binding Source: Ensembl
- SMAD binding Source: Ensembl
- transcription corepressor binding Source: Ensembl
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 101 | BTBInterPro annotationAdd BLAST | 68 | |
Domaini | 375 – 402 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 217 – 309 | DisorderedSequence analysisAdd BLAST | 93 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000162053 |
HOGENOMi | CLU_025627_2_1_1 |
InParanoidi | I3N9P3 |
OrthoDBi | 1318335at2759 |
TreeFami | TF331824 |
Family and domain databases
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit |
SMARTi | View protein in SMART SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 1 hit |
i Sequence
Sequence statusi: Complete.
I3N9P3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGGVDGPIG IPFPDHSSDI LSGLNEQRTQ GLLCDVVILV EGREFPTHRS
60 70 80 90 100
VLAACSQYFK KLFTSGAVVD QQNVYEIDFV SAEALTALMD FAYTATLTVS
110 120 130 140 150
TANVGDILSA ARLLEIPAVS HVCADLLDRQ ILAADAGADA GQLELVDQVG
160 170 180 190 200
QRNLLRAKEY LEFFQSNPMN SLPPAAAAAF PWPAFGASED DLDATKEAVA
210 220 230 240 250
AAVAAVAAGD CNGLDFYGPG PPAERPPAGD GDEGDSNPGL WPERDEDAPT
260 270 280 290 300
GGLFPPPAAP PATTQNGHYS RGGEEEAASL SEAAPEPGDS PGFLSGAAEG
310 320 330 340 350
EDGDAPDVDG LAASTLLQQM MSSVGRTGDS DEESRADDKG VMDYYLKYFS
360 370 380 390 400
SAHEGDVYPA WSQKGEKKIR AKAFQKCPIC EKVIQGAGKL PRHIRTHTGE
410
KPYECSICKV RFTR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AGTP01068849 Genomic DNA No translation available. AGTP01068850 Genomic DNA No translation available. |
RefSeqi | XP_005332269.1, XM_005332212.1 |
Genome annotation databases
Ensembli | ENSSTOT00000026595; ENSSTOP00000021090; ENSSTOG00000026956 |
GeneIDi | 101974495 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AGTP01068849 Genomic DNA No translation available. AGTP01068850 Genomic DNA No translation available. |
RefSeqi | XP_005332269.1, XM_005332212.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSSTOT00000026595; ENSSTOP00000021090; ENSSTOG00000026956 |
GeneIDi | 101974495 |
Organism-specific databases
CTDi | 51341 |
Phylogenomic databases
GeneTreei | ENSGT00940000162053 |
HOGENOMi | CLU_025627_2_1_1 |
InParanoidi | I3N9P3 |
OrthoDBi | 1318335at2759 |
TreeFami | TF331824 |
Family and domain databases
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit |
SMARTi | View protein in SMART SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | I3N9P3_ICTTR | |
Accessioni | I3N9P3Primary (citable) accession number: I3N9P3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 11, 2012 |
Last sequence update: | November 22, 2017 | |
Last modified: | October 7, 2020 | |
This is version 55 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |