Uncharacterized protein

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• activating transcription factor binding Source: Ensembl
• androgen receptor binding Source: Ensembl
• DNA-binding transcription repressor activity, RNA polymerase II-specific Source: Ensembl
• histone acetyltransferase binding Source: Ensembl
• RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: Ensembl
• SMAD binding Source: Ensembl
• transcription corepressor binding Source: Ensembl

GO - Biological processⁱ

• B cell differentiation Source: Ensembl
• chromatin remodeling Source: Ensembl
• double-strand break repair via classical nonhomologous end joining Source: Ensembl
• erythrocyte maturation Source: Ensembl
• fat cell differentiation Source: Ensembl
• negative regulation of androgen receptor signaling pathway Source: Ensembl
• negative regulation of Notch signaling pathway Source: Ensembl
• negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
• positive regulation of NF-kappaB transcription factor activity Source: Ensembl
• protein localization to nucleus Source: Ensembl
• regulation of alternative mRNA splicing, via spliceosome Source: Ensembl
• regulation of apoptotic process Source: Ensembl
• regulation of glycolytic process Source: Ensembl
• regulation of transcription regulatory region DNA binding Source: Ensembl
• transcription, DNA-templated Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• activating transcription factor binding Source: Ensembl
• androgen receptor binding Source: Ensembl
• histone acetyltransferase binding Source: Ensembl
• SMAD binding Source: Ensembl
• transcription corepressor binding Source: Ensembl

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MAGGVDGPIG IPFPDHSSDI LSGLNEQRTQ GLLCDVVILV EGREFPTHRS 
        60         70         80         90        100
VLAACSQYFK KLFTSGAVVD QQNVYEIDFV SAEALTALMD FAYTATLTVS 
       110        120        130        140        150
TANVGDILSA ARLLEIPAVS HVCADLLDRQ ILAADAGADA GQLELVDQVG 
       160        170        180        190        200
QRNLLRAKEY LEFFQSNPMN SLPPAAAAAF PWPAFGASED DLDATKEAVA 
       210        220        230        240        250
AAVAAVAAGD CNGLDFYGPG PPAERPPAGD GDEGDSNPGL WPERDEDAPT 
       260        270        280        290        300
GGLFPPPAAP PATTQNGHYS RGGEEEAASL SEAAPEPGDS PGFLSGAAEG 
       310        320        330        340        350
EDGDAPDVDG LAASTLLQQM MSSVGRTGDS DEESRADDKG VMDYYLKYFS 
       360        370        380        390        400
SAHEGDVYPA WSQKGEKKIR AKAFQKCPIC EKVIQGAGKL PRHIRTHTGE 
       410 
KPYECSICKV RFTR                                        

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ