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Protein
Submitted name:

Neurolysin

Gene

NLN

Organism
Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotationSAAS annotation, Protease
LigandMetal-bindingUniRule annotationSAAS annotation, ZincUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NeurolysinImported
Gene namesi
Name:NLNImported
OrganismiIctidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)Imported
Taxonomic identifieri43179 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciuromorphaSciuridaeXerinaeMarmotiniIctidomys
Proteomesi
  • UP000005215 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi43179.ENSSTOP00000016664

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini251 – 700Peptidase_M3InterPro annotationAdd BLAST450

Sequence similaritiesi

Belongs to the peptidase M3 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2089 Eukaryota
COG0339 LUCA
GeneTreeiENSGT00550000074738
InParanoidiI3MX19
OrthoDBiEOG091G0325
TreeFamiTF300459

Family and domain databases

Gene3Di1.10.1370.10, 2 hits
1.20.1050.40, 1 hit
3.40.390.10, 1 hit
InterProiView protein in InterPro
IPR024079 MetalloPept_cat_dom_sf
IPR024077 Neurolysin/TOP_dom2
IPR024080 Neurolysin/TOP_N
IPR001567 Pept_M3A_M3B
PfamiView protein in Pfam
PF01432 Peptidase_M3, 1 hit

Sequencei

Sequence statusi: Complete.

I3MX19-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIARCLLAVR GLHRVGGSRI LLRMTLGREV TSSLQTVSSY TAAGRNVLRW
60 70 80 90 100
DLSPEQIKTR TEELIVQTKQ VYDAVGMLNV EEVTYENCLQ VLADVEVKYI
110 120 130 140 150
VERTMLDFPQ HVSSDKEVRA ASTEADKRLS RFDIEMSMRE DIFKRIVHLQ
160 170 180 190 200
ETCDLEKIKP EARRYLEKSV KMGKRNGLHL PEQVQNEIKS MKKKMSELCI
210 220 230 240 250
DFNKNLNEDD TFLVFSKAEL GALPDDFIDS LEKTGDDKYK ITLKYPHYFP
260 270 280 290 300
VMKKCCVPET RRKMEMAFNT RCKEENTIIL QQLLPLRAQV AKLLGYNTHA
310 320 330 340 350
DFVLEMNTAK STSHVTTFLD DLSRKLKPLG EAEREFILNL KKKECKERGF
360 370 380 390 400
EYDGKINAWD LHYYMTQTEE LKYSIDQESL KEYFPIEVVT EGLLNIYQEL
410 420 430 440 450
LGLSFEQVTD AHVWNKSVTL YTVKDKATGE VLGQFYLDLY PREGKYNHAA
460 470 480 490 500
CFGLQPGCLL PDGNRMMSVA ALVVNFSQPV AGRPSLLRHD EVRTYFHEFG
510 520 530 540 550
HVMHQICAQT EFARFSGTNV ETDFVEVPSQ MLENWVWDID SLRRLSKHYK
560 570 580 590 600
DGSPITDDLL EKLVASRLVN TGLLTLRQIV LSKVDQSLHT NTSLDAASEY
610 620 630 640 650
AKYCTEILGV AATPGTNMPA TFGHLAGGYD GQYYGYLWSE VFSTDMFYSC
660 670 680 690 700
FKKEGIMNPE VGMKYRNLIL KPGGSLDGMD MLQNFLKREP NQKAFLMSRG

LCAP
Length:704
Mass (Da):80,591
Last modified:November 22, 2017 - v2
Checksum:i417981A5CA82E6F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGTP01014026 Genomic DNA No translation available.
AGTP01014027 Genomic DNA No translation available.
RefSeqiXP_005319615.1, XM_005319558.2

Genome annotation databases

EnsembliENSSTOT00000022807; ENSSTOP00000016664; ENSSTOG00000027725
GeneIDi101965900

Similar proteinsi

Entry informationi

Entry nameiI3MX19_ICTTR
AccessioniPrimary (citable) accession number: I3MX19
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: November 22, 2017
Last modified: May 23, 2018
This is version 39 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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