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Protein
Submitted name:

Nuclear receptor subfamily 3 group C member 2

Gene

NR3C2

Organism
Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi600 – 675Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiIctidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)Imported
Taxonomic identifieri43179 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciuromorphaSciuridaeXerinaeMarmotiniIctidomys
Proteomesi
  • UP000005215 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi43179.ENSSTOP00000003652

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini600 – 675Nuclear receptorInterPro annotationAdd BLAST76
Domaini727 – 965NR LBDInterPro annotationAdd BLAST239

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
InParanoidiI3M3J5
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

I3M3J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKGYHSLP EGLDMERRWS QVSQAVEQSS LGPTERTDES NYMEIVNVSS
60 70 80 90 100
VSGAIPNSST QGSSKEKHEL LPCLQQDNNR SGTLTSDIKT ELESKELSAT
110 120 130 140 150
VAESMGLYMD SVRDADYAFD QQNQQGSGSP AKIYQNVEQL VKFYKENGHR
160 170 180 190 200
PSTLSSVSRP LRSFMSDSGS SMNSGVMRAI VKSPIMCHDK SPSVCSPLNM
210 220 230 240 250
TSSVCSPAGI NSVSSTTTSF GSFSVHSPIT QGTPLTCSPN IENRSSRSHS
260 270 280 290 300
PAHASNVGSP LSSPLSSMKS PISSPPSHCS VKSPVSSPNN ATLRSSVSSP
310 320 330 340 350
ANLNNSRCSV SSPSNTNNRS TLSSPTASTV GSICSPINNA FSYPASGTSA
360 370 380 390 400
GAGATRDVVP SPDTHEKGAH EIPFPKTEEV ENAISNGVTG QLNIVQYIKP
410 420 430 440 450
EPDGAFSSSC LGGNSKINSE SPFSVPIKQE STKHSCSGTS FKGNPTVNPF
460 470 480 490 500
PFMDGSYFSF MDDKDYYSLS GILGPPVPGF DGNCEGSGFP MGIKQEPDDG
510 520 530 540 550
SYYPEASIPS SAIVGVNSSG QSFHYRIGAQ GTISLSRSAR DQSFQHLSSF
560 570 580 590 600
PPVSTLVESW KSHGDLSSRR SDGYPVLEYI PENVSSSTLR SVSTGSSRPS
610 620 630 640 650
KICLVCGDEA SGCHYGVVTC GSCKVFFKRA VEGQHNYLCA GRNDCIIDKI
660 670 680 690 700
RRKNCPACRL QKCLQAGMNL GARKSKKLGK LKGIHEDQPP QQQQQQPPPP
710 720 730 740 750
PPQSPEEGTT YIAPAKEPSV NTALVPQLST ISRALTPSPV MVLESIEPET
760 770 780 790 800
VYAGYDSSKP DTAENLLSTL NRLAGKQMIQ VVKWAKVLPG FKNLPLEDQI
810 820 830 840 850
TLIQYSWMCL SSFALSWRSY KHTNSQFLYF APDLVFNEEK MHQSAMYELC
860 870 880 890 900
QGMHQISLQF VRLQLTFEEY AIMKVLLLLS TVPKDGLKCQ AAFEEMRANY
910 920 930 940 950
IKELRKMVTK CPNNSGQSWQ RFYQLTKLLD SMHDLVSDLL EFCFYTFRES
960 970 980
QALKVEFPAM LVEIISDQLP KVESGNAKAL YFHRK
Length:985
Mass (Da):107,155
Last modified:November 22, 2017 - v2
Checksum:i94A70FE418146F95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGTP01049025 Genomic DNA No translation available.
AGTP01049026 Genomic DNA No translation available.
AGTP01049027 Genomic DNA No translation available.
AGTP01049028 Genomic DNA No translation available.
AGTP01049029 Genomic DNA No translation available.
AGTP01049030 Genomic DNA No translation available.
AGTP01049031 Genomic DNA No translation available.
AGTP01049032 Genomic DNA No translation available.
AGTP01049033 Genomic DNA No translation available.
AGTP01049034 Genomic DNA No translation available.
RefSeqiXP_005327588.1, XM_005327531.1

Genome annotation databases

EnsembliENSSTOT00000004072; ENSSTOP00000003652; ENSSTOG00000004069
GeneIDi101972102

Similar proteinsi

Entry informationi

Entry nameiI3M3J5_ICTTR
AccessioniPrimary (citable) accession number: I3M3J5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: November 22, 2017
Last modified: June 20, 2018
This is version 52 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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