Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 44 (08 May 2019)
Sequence version 2 (22 Nov 2017)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

PER3

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PER3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008227 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
I3LSH1

PRoteomics IDEntifications database

More...
PRIDEi
I3LSH1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000028572 Expressed in 5 organ(s), highest expression level in prefrontal cortex

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000027064

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini300 – 346PASInterPro annotationAdd BLAST47

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3753 Eukaryota
ENOG410Y118 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160817

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
I3LSH1

Identification of Orthologs from Complete Genome Data

More...
OMAi
VFYTHTA

TreeFam database of animal gene trees

More...
TreeFami
TF318445

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00130 PAS, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013655 PAS_fold_3
IPR015524 Per_circ_prot_3
IPR022728 Period_circadian-like_C

The PANTHER Classification System

More...
PANTHERi
PTHR11269:SF13 PTHR11269:SF13, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08447 PAS_3, 1 hit
PF12114 Period_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00091 PAS, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55785 SSF55785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50112 PAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

I3LSH1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEACEDLEMS RSKSQNPRGN QRPELEGPQA SGPEALGKDS AEMWHQKHQL
60 70 80 90 100
QGKYTETSHS EQQDRDRVFE ELITVVQEMK THFPSARHSK PSTLDALNYA
110 120 130 140 150
LRCVHSVQAN SEFFQSLRQN NGAPQADVTV YRPEELATIA SEHASKNTDT
160 170 180 190 200
FVAVFSFLSG RLVHISEQAP SVLNCRKELL ESSPFAELLA PQDVGVFYSH
210 220 230 240 250
TAHAQLPFWN NWTQRASPHD LAPVKSFFCR IRGGDAGKPE RLYGPFRIVP
260 270 280 290 300
YLIHLHSPAR PEPEPCCLLL VEKVRSGYTA PRIPENKRVF TTTHTPGCVF
310 320 330 340 350
LEIDERAVPL LGYLPQDLIG TSILTHLHPE DAALMLAVHQ KVLKLAGQPP
360 370 380 390 400
FDHSPIRFCS QNGDYIILDS SWSSFVNPWS RKISLIIGQH QVRTSPLNED
410 420 430 440 450
VFATRIKKMN SNDKDITELQ EQIHKLLLQP VRGGSPADGG CGSLGSSGSP
460 470 480 490 500
EHPVSLASSS GSSGRCEEEP RAASTLQQVH ASVDKVKTPG QQLYSESMTK
510 520 530 540 550
SPKKQVTGTR TAGPGGEQEA FSSFQTLKND RMCTESCEDL ETDQHSPSYQ
560 570 580 590 600
QINCIDSVIR FLKSHDMPAL KRKCRSYTNT ASSSSGEDGP NPGAGEAPAQ
610 620 630 640 650
PAASRIPATP ASGVPATGWP IDAVGGAPGP VDTTALDLDV SQSSDCSTIV
660 670 680 690 700
HILPPESELT AAVDGTPACE PWTLNRHPAP LLPEDFKHRG LTEAVPSAHM
710 720 730 740 750
QKEEQSYVDK FREKVPSSPY SLCLQQENGG KTKYAHGQGD PAPPPTRSAG
760 770 780 790 800
CKKGKPRRKK LLLLSDSKGA EDSICPPLRP EVQAGQPWCP ASASSPQASG
810 820 830 840 850
LSLAAAVMVP SPAPYMFPAL SLPAVTSVGG EGAASGPAPP GPPEPPVPRG
860 870 880 890 900
SWSLPALPSA CLDPFMNLFL HDPPVCALLS PSFASDPFLG APGTSELPPS
910 920 930 940 950
VSALAADLDA ASSFISERPG EEKWGAQSEA HPLGLSGASS PLQLSLLRGD
960 970 980 990 1000
RPRSGEASGP VRSDVCLEAE RCVGGPSGNK NSYFTASDLP TVSLHKTSPP
1010 1020 1030 1040 1050
ETGSAATGGQ QSQDEQRKET FPGLADDSIW RMIEQTPECV LMTYQVPKRV
1060 1070 1080 1090 1100
KEIVLREDLE KLESMRRRQP HFSHGQRKEL AAVYAWIQSQ TVPQERDTQI
Length:1,100
Mass (Da):119,014
Last modified:November 22, 2017 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i51138BFB96F08AA8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEMK02000044 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000027190; ENSSSCP00000027064; ENSSSCG00000028572

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000044 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000027064

Proteomic databases

PaxDbiI3LSH1
PRIDEiI3LSH1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000027190; ENSSSCP00000027064; ENSSSCG00000028572

Phylogenomic databases

eggNOGiKOG3753 Eukaryota
ENOG410Y118 LUCA
GeneTreeiENSGT00940000160817
InParanoidiI3LSH1
OMAiVFYTHTA
TreeFamiTF318445

Gene expression databases

BgeeiENSSSCG00000028572 Expressed in 5 organ(s), highest expression level in prefrontal cortex

Family and domain databases

CDDicd00130 PAS, 1 hit
InterProiView protein in InterPro
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013655 PAS_fold_3
IPR015524 Per_circ_prot_3
IPR022728 Period_circadian-like_C
PANTHERiPTHR11269:SF13 PTHR11269:SF13, 1 hit
PfamiView protein in Pfam
PF08447 PAS_3, 1 hit
PF12114 Period_C, 1 hit
SMARTiView protein in SMART
SM00091 PAS, 2 hits
SUPFAMiSSF55785 SSF55785, 1 hit
PROSITEiView protein in PROSITE
PS50112 PAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI3LSH1_PIG
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I3LSH1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: November 22, 2017
Last modified: May 8, 2019
This is version 44 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again