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Entry version 72 (29 Sep 2021)
Sequence version 2 (22 Nov 2017)
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Protein

DNA-directed RNA polymerase subunit beta

Gene

POLR2B

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotationARBA annotation, Transferase
Biological processTranscription
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SSC-112382, Formation of RNA Pol II elongation complex
R-SSC-113418, Formation of the Early Elongation Complex
R-SSC-5578749, Transcriptional regulation by small RNAs
R-SSC-674695, RNA Polymerase II Pre-transcription Events
R-SSC-6781823, Formation of TC-NER Pre-Incision Complex
R-SSC-6782135, Dual incision in TC-NER
R-SSC-6782210, Gap-filling DNA repair synthesis and ligation in TC-NER
R-SSC-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-SSC-6803529, FGFR2 alternative splicing
R-SSC-6807505, RNA polymerase II transcribes snRNA genes
R-SSC-72086, mRNA Capping
R-SSC-72163, mRNA Splicing - Major Pathway
R-SSC-72165, mRNA Splicing - Minor Pathway
R-SSC-72203, Processing of Capped Intron-Containing Pre-mRNA
R-SSC-73776, RNA Polymerase II Promoter Escape
R-SSC-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-SSC-75953, RNA Polymerase II Transcription Initiation
R-SSC-75955, RNA Polymerase II Transcription Elongation
R-SSC-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance
R-SSC-77075, RNA Pol II CTD phosphorylation and interaction with CE
R-SSC-9018519, Estrogen-dependent gene expression

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:POLR2BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008227 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:91647, POLR2B

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymeraseUniRule annotationARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
I3LGP4

PeptideAtlas

More...
PeptideAtlasi
I3LGP4

PRoteomics IDEntifications database

More...
PRIDEi
I3LGP4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000022955, Expressed in adipose tissue and 49 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
I3LGP4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
I3LGP4, SS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000023238

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
I3LGP4

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini115 – 518RNA_pol_Rpb2_1InterPro annotationAdd BLAST404
Domaini278 – 471RNA_pol_Rpb2_2InterPro annotationAdd BLAST194
Domaini545 – 609RNA_pol_Rpb2_3InterPro annotationAdd BLAST65
Domaini644 – 706RNA_pol_Rpb2_4InterPro annotationAdd BLAST63
Domaini730 – 777RNA_pol_Rpb2_5InterPro annotationAdd BLAST48
Domaini784 – 1157RNA_pol_Rpb2_6InterPro annotationAdd BLAST374
Domaini1159 – 1249RNA_pol_Rpb2_7InterPro annotationAdd BLAST91

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotationARBA annotation

Keywords - Domaini

Zinc-fingerARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0214, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183132

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000524_5_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
I3LGP4

Identification of Orthologs from Complete Genome Data

More...
OMAi
EIMYNGH

Database of Orthologous Groups

More...
OrthoDBi
42570at2759

TreeFam database of animal gene trees

More...
TreeFami
TF103037

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00653, RNA_pol_B_RPB2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.270.10, 1 hit
2.40.50.150, 1 hit
3.90.1110.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015712, DNA-dir_RNA_pol_su2
IPR007120, DNA-dir_RNAP_su2_dom
IPR037033, DNA-dir_RNAP_su2_hyb_sf
IPR007121, RNA_pol_bsu_CS
IPR007644, RNA_pol_bsu_protrusion
IPR007642, RNA_pol_Rpb2_2
IPR037034, RNA_pol_Rpb2_2_sf
IPR007645, RNA_pol_Rpb2_3
IPR007646, RNA_pol_Rpb2_4
IPR007647, RNA_pol_Rpb2_5
IPR007641, RNA_pol_Rpb2_7
IPR014724, RNA_pol_RPB2_OB-fold

The PANTHER Classification System

More...
PANTHERi
PTHR20856, PTHR20856, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04563, RNA_pol_Rpb2_1, 1 hit
PF04561, RNA_pol_Rpb2_2, 1 hit
PF04565, RNA_pol_Rpb2_3, 1 hit
PF04566, RNA_pol_Rpb2_4, 1 hit
PF04567, RNA_pol_Rpb2_5, 1 hit
PF00562, RNA_pol_Rpb2_6, 1 hit
PF04560, RNA_pol_Rpb2_7, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01166, RNA_POL_BETA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

I3LGP4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCSTNLSQAL AYFRAGANLT AASLWAGFRG SRRIFWERRK RKSLCLALRP
60 70 80 90 100
GGACWRWLLA VSCVSLRGLG APGSCANMYD ADEDMQYDED DDEITPDLWQ
110 120 130 140 150
EACWIVISSY FDEKGLVRQQ LDSFDEFIQM SVQRIVEDAP PIDLQAEAQH
160 170 180 190 200
ASGEVEEPPR YLLKFEQIYL SKPTHWERDG APSPMMPNEA RLRNLTYSAP
210 220 230 240 250
LYVDITKTVI KEGEEQLQTQ HQKTFIGKIP IMLRSTYCLL NGLTDRDLCE
260 270 280 290 300
LNECPLDPGG YFIINGSEKV LIAQEKMATN TVYVFAKKDS KYAYTGECRS
310 320 330 340 350
CLENSSRPTS TIWVSMLARG GQGAKKSAIG QRIVATLPYI KQEVPIIIVF
360 370 380 390 400
RALGFVSDRD ILEHIIYDFE DPEMMEMVKP SLDEAFVIQE QNVALNFIGS
410 420 430 440 450
RGAKPGVTKE KRIKYAKEVL QKEMLPHVGV SDFCETKKAY FLGYMVHRLL
460 470 480 490 500
LAALGRRELD DRDHYGNKRL DLAGPLLAFL FRGMFKNLLK EVRIYAQKFI
510 520 530 540 550
DRGKDFNLEL AIKTRIISDG LKYSLATGNW GDQKKAHQAR AGVSQVLNRL
560 570 580 590 600
TFASTLSHLR RLNSPIGRDG KLAKPRQLHN TLWGMVCPAE TPEGHAVGLV
610 620 630 640 650
KNLALMAYIS VGSQPSPILE FLEEWSMENL EEISPAAIAD ATKIFVNGCW
660 670 680 690 700
VGIHKDPEQL MNTLRKLRRQ MDIIVSEVSM IRDIREREIR IYTDAGRICR
710 720 730 740 750
PLLIVEKQKL LLKKRHIDQL KEREYNNYSW QDLVASGVVE YIDTLEEETV
760 770 780 790 800
MLAMTPDDLQ EKEVAYCSTY THCEIHPSMI LGVCASIIPF PDHNQSPRNT
810 820 830 840 850
YQSAMGKQAM GVYITNFHVR MDTLAHVLYY PQKPLVTTRS MEYLRFRELP
860 870 880 890 900
AGINSIVAIA SYTGYNQEDS VIMNRSAVDR GFFRSVFYRS YKEQESKKGF
910 920 930 940 950
DQEEVFEKPT RETCQGMRHA IYDKLDDDGL IAPGVRVSGD DVIIGKTVTL
960 970 980 990 1000
PENEDELEGT NRRYTKRDCS TFLRTSETGI VDQVMVTLNQ EGYKFCKIRV
1010 1020 1030 1040 1050
RSVRIPQIGD KFASRHGQKG TCGIQYRQED MPFTCEGITP DIIINPHAIP
1060 1070 1080 1090 1100
SRMTIGHLIE CLQGKVSANK GEIGDATPFN DAVNVQKISN LLSDYGYHLR
1110 1120 1130 1140 1150
GNEVLYNGFT GRKITSQIFI GPTYYQRLKH MVDDKIHSRA RGPIQILNRQ
1160 1170 1180 1190 1200
PMEGRSRDGG LRFGEMERDC QIAHGAAQFL RERLFEASDP YQVHVCNLCG
1210 1220 1230 1240 1250
IMAIANTRTH TYECRGCRNK TQISLVRMPY ACKLLFQELM SMSIAPRMMS

V
Length:1,251
Mass (Da):142,239
Last modified:November 22, 2017 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA2157D7E8FDDA0D9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEMK02000066 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000023257; ENSSSCP00000023238; ENSSSCG00000022955

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000066 Genomic DNA No translation available.

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6EXVelectron microscopy3.60B85-1251[»]
6GMHelectron microscopy3.10B78-1251[»]
6GMLelectron microscopy3.20B78-1251[»]
6TEDelectron microscopy3.10B1-1251[»]
7NVRelectron microscopy4.50B78-1251[»]
7NVSelectron microscopy2.80B78-1251[»]
7NVTelectron microscopy2.90B78-1251[»]
7NVUelectron microscopy2.50B78-1251[»]
7NVYelectron microscopy7.30B78-1251[»]
7NVZelectron microscopy7.20B78-1251[»]
7NW0electron microscopy6.60B78-1251[»]
SMRiI3LGP4
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000023238

Proteomic databases

PaxDbiI3LGP4
PeptideAtlasiI3LGP4
PRIDEiI3LGP4

Genome annotation databases

EnsembliENSSSCT00000023257; ENSSSCP00000023238; ENSSSCG00000022955

Organism-specific databases

VGNCiVGNC:91647, POLR2B

Phylogenomic databases

eggNOGiKOG0214, Eukaryota
GeneTreeiENSGT00950000183132
HOGENOMiCLU_000524_5_2_1
InParanoidiI3LGP4
OMAiEIMYNGH
OrthoDBi42570at2759
TreeFamiTF103037

Enzyme and pathway databases

ReactomeiR-SSC-112382, Formation of RNA Pol II elongation complex
R-SSC-113418, Formation of the Early Elongation Complex
R-SSC-5578749, Transcriptional regulation by small RNAs
R-SSC-674695, RNA Polymerase II Pre-transcription Events
R-SSC-6781823, Formation of TC-NER Pre-Incision Complex
R-SSC-6782135, Dual incision in TC-NER
R-SSC-6782210, Gap-filling DNA repair synthesis and ligation in TC-NER
R-SSC-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-SSC-6803529, FGFR2 alternative splicing
R-SSC-6807505, RNA polymerase II transcribes snRNA genes
R-SSC-72086, mRNA Capping
R-SSC-72163, mRNA Splicing - Major Pathway
R-SSC-72165, mRNA Splicing - Minor Pathway
R-SSC-72203, Processing of Capped Intron-Containing Pre-mRNA
R-SSC-73776, RNA Polymerase II Promoter Escape
R-SSC-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-SSC-75953, RNA Polymerase II Transcription Initiation
R-SSC-75955, RNA Polymerase II Transcription Elongation
R-SSC-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance
R-SSC-77075, RNA Pol II CTD phosphorylation and interaction with CE
R-SSC-9018519, Estrogen-dependent gene expression

Gene expression databases

BgeeiENSSSCG00000022955, Expressed in adipose tissue and 49 other tissues
ExpressionAtlasiI3LGP4, baseline and differential
GenevisibleiI3LGP4, SS

Family and domain databases

CDDicd00653, RNA_pol_B_RPB2, 1 hit
Gene3Di2.40.270.10, 1 hit
2.40.50.150, 1 hit
3.90.1110.10, 1 hit
InterProiView protein in InterPro
IPR015712, DNA-dir_RNA_pol_su2
IPR007120, DNA-dir_RNAP_su2_dom
IPR037033, DNA-dir_RNAP_su2_hyb_sf
IPR007121, RNA_pol_bsu_CS
IPR007644, RNA_pol_bsu_protrusion
IPR007642, RNA_pol_Rpb2_2
IPR037034, RNA_pol_Rpb2_2_sf
IPR007645, RNA_pol_Rpb2_3
IPR007646, RNA_pol_Rpb2_4
IPR007647, RNA_pol_Rpb2_5
IPR007641, RNA_pol_Rpb2_7
IPR014724, RNA_pol_RPB2_OB-fold
PANTHERiPTHR20856, PTHR20856, 1 hit
PfamiView protein in Pfam
PF04563, RNA_pol_Rpb2_1, 1 hit
PF04561, RNA_pol_Rpb2_2, 1 hit
PF04565, RNA_pol_Rpb2_3, 1 hit
PF04566, RNA_pol_Rpb2_4, 1 hit
PF04567, RNA_pol_Rpb2_5, 1 hit
PF00562, RNA_pol_Rpb2_6, 1 hit
PF04560, RNA_pol_Rpb2_7, 1 hit
PROSITEiView protein in PROSITE
PS01166, RNA_POL_BETA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI3LGP4_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I3LGP4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: November 22, 2017
Last modified: September 29, 2021
This is version 72 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Proteomics identificationCombined sources, Reference proteomeImported
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