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Protein
Submitted name:

Insulin-like growth factor-binding protein 3 receptor

Gene

TMEM219

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor-binding protein 3 receptorImported
Gene namesi
Name:TMEM219Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000149932.16
HGNCiHGNC:25201 TMEM219

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149932

PTM / Processingi

Proteomic databases

EPDiI3L4B3
PeptideAtlasiI3L4B3
PRIDEiI3L4B3

Expressioni

Gene expression databases

BgeeiENSG00000149932 Expressed in 197 organ(s), highest expression level in body of stomach
ExpressionAtlasiI3L4B3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliI3L4B3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 112TMEM219InterPro annotationAdd BLAST68

Phylogenomic databases

eggNOGiENOG410IWEC Eukaryota
ENOG4110155 LUCA
GeneTreeiENSGT00390000013671

Family and domain databases

InterProiView protein in InterPro
IPR039493 TMEM248/TMEM219
IPR039587 TMEM248/TMEM219_dom
PANTHERiPTHR16002 PTHR16002, 1 hit
PfamiView protein in Pfam
PF14940 TMEM219, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

I3L4B3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DWVSFLRSFG QLTLCPRNGT VTGKWRGSHV VGLLTTLNFG DGPDRNKTRT
60 70 80 90 100
FQATVLGSQM GLKGSSAGQL VLITARVTTE RTAGTCLYFS AVPGILPSSQ
110 120 130 140 150
PPISCSEEGA GNATLSPRMG EECVSVWSHE GLVLTKLLTS VRASDGSPGF
160
CRLPADYCIL KVPGNNSTL
Length:169
Mass (Da):17,862
Last modified:July 11, 2012 - v1
Checksum:i0028BB86DC4C83B7
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q86XT9TM219_HUMAN
Insulin-like growth factor-binding ...
TMEM219
240Annotation score:
I3L2J7I3L2J7_HUMAN
Insulin-like growth factor-binding ...
TMEM219
213Annotation score:
I3L2P0I3L2P0_HUMAN
Insulin-like growth factor-binding ...
TMEM219
231Annotation score:
R4GNJ4R4GNJ4_HUMAN
Insulin-like growth factor-binding ...
TMEM219
149Annotation score:
H3BML8H3BML8_HUMAN
Insulin-like growth factor-binding ...
TMEM219
99Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093512 Genomic DNA No translation available.
AC120114 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000569445; ENSP00000461124; ENSG00000149932
UCSCiuc059sxa.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093512 Genomic DNA No translation available.
AC120114 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliI3L4B3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiI3L4B3
PeptideAtlasiI3L4B3
PRIDEiI3L4B3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000569445; ENSP00000461124; ENSG00000149932
UCSCiuc059sxa.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000149932.16
HGNCiHGNC:25201 TMEM219
OpenTargetsiENSG00000149932
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IWEC Eukaryota
ENOG4110155 LUCA
GeneTreeiENSGT00390000013671

Gene expression databases

BgeeiENSG00000149932 Expressed in 197 organ(s), highest expression level in body of stomach
ExpressionAtlasiI3L4B3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR039493 TMEM248/TMEM219
IPR039587 TMEM248/TMEM219_dom
PANTHERiPTHR16002 PTHR16002, 1 hit
PfamiView protein in Pfam
PF14940 TMEM219, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI3L4B3_HUMAN
AccessioniPrimary (citable) accession number: I3L4B3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: October 10, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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