UniProtKB - I3L417 (I3L417_HUMAN)
Protein
Submitted name:
Zinc finger protein 205
Gene
ZNF205
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 205Imported |
Gene namesi | Name:ZNF205Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:12996, ZNF205 |
VEuPathDBi | HostDB:ENSG00000122386.10 |
Expressioni
Gene expression databases
Bgeei | ENSG00000122386, Expressed in tendon of biceps brachii and 221 other tissues |
ExpressionAtlasi | I3L417, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 50 – 131 | KRABInterPro annotationAdd BLAST | 82 | |
Domaini | 197 – 224 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 225 – 252 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 129 – 192 | DisorderedSequence analysisAdd BLAST | 64 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 148 – 164 | Pro-richSequence analysisAdd BLAST | 17 | |
Compositional biasi | 166 – 192 | PolyampholyteSequence analysisAdd BLAST | 27 |
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000161865 |
HOGENOMi | CLU_1096392_0_0_1 |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 2 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 2 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
I3L417-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XLSHGSKEKA LFLPGGALPS PRIPVLSREG RTRDRQMAAA LLTAWSQMPV
60 70 80 90 100
TFEDVALYLS REEWGRLDHT QQNFYRDVLQ KKNGLSLGAV EVGQRVQTSS
110 120 130 140 150
VAALGNVKPF RTRAGRVQWG VPQCAQEAAC GRSSGPAKDS GQPAEPDRTP
160 170 180 190 200
DAAPPDPSPT EPQEYRVPEK PNEEEKGAPE SGEEGLAPDS EVGRKSYRCE
210 220 230 240 250
QCGKGFSWHS HLVTHRRTHT GEKPYACTDC GKRFGRSSHL IQHQIIHTGE
KPYTC
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO95201 | ZN205_HUMAN | Zinc finger protein 205 | ZNF205 ZNF210 | 554 | Annotation score: | ||
C9JEY6 | C9JEY6_HUMAN | Zinc finger protein 205 | ZNF205 | 278 | Annotation score: | ||
C9JS60 | C9JS60_HUMAN | Zinc finger protein 205 | ZNF205 | 118 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 255 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC108134 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000570935; ENSP00000460890; ENSG00000122386 |
UCSCi | uc059pvm.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC108134 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | I3L417 |
PRIDEi | I3L417 |
ProteomicsDBi | 47380 |
Protocols and materials databases
Antibodypediai | 822, 105 antibodies |
Genome annotation databases
Ensembli | ENST00000570935; ENSP00000460890; ENSG00000122386 |
UCSCi | uc059pvm.1, human |
Organism-specific databases
HGNCi | HGNC:12996, ZNF205 |
OpenTargetsi | ENSG00000122386 |
VEuPathDBi | HostDB:ENSG00000122386.10 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161865 |
HOGENOMi | CLU_1096392_0_0_1 |
Miscellaneous databases
ChiTaRSi | ZNF205, human |
Gene expression databases
Bgeei | ENSG00000122386, Expressed in tendon of biceps brachii and 221 other tissues |
ExpressionAtlasi | I3L417, baseline and differential |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 2 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | I3L417_HUMAN | |
Accessioni | I3L417Primary (citable) accession number: I3L417 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 11, 2012 |
Last sequence update: | October 5, 2016 | |
Last modified: | February 10, 2021 | |
This is version 64 of the entry and version 8 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |