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Protein
Submitted name:

Caspase recruitment domain family, member 14, isoform CRA_d

Gene

CARD14

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase recruitment domain family, member 14, isoform CRA_dImported
Submitted name:
Caspase recruitment domain-containing protein 14Imported
Gene namesi
Name:CARD14Imported
ORF Names:hCG_28572Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000141527.16
HGNCiHGNC:16446 CARD14

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000141527

PTM / Processingi

Proteomic databases

MaxQBiI3L414
PeptideAtlasiI3L414
PRIDEiI3L414

Expressioni

Gene expression databases

BgeeiENSG00000141527 Expressed in 126 organ(s), highest expression level in ectocervix
ExpressionAtlasiI3L414 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 107CARDInterPro annotationAdd BLAST93

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili132 – 159Sequence analysisAdd BLAST28
Coiled coili205 – 239Sequence analysisAdd BLAST35
Coiled coili257 – 277Sequence analysisAdd BLAST21
Coiled coili284 – 325Sequence analysisAdd BLAST42

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0708 Eukaryota
COG0194 LUCA
GeneTreeiENSGT00530000063108

Family and domain databases

InterProiView protein in InterPro
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

I3L414-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGELCRRDSA LTALDEETLW EMMESHRHRI VRCICPSRLT PYLRQAKVLC
60 70 80 90 100
QLDEEEVLHS PRLTNSAMRA GHLLDLLKTR GKNGAIAFLE SLKFHNPDVY
110 120 130 140 150
TLVTGLQPDV DFSNFSGLME TSKLTECLAG AIGSLQEELN QEKGQKEVLL
160 170 180 190 200
RRCQQLQEHL GLAETRAEGL HQLEADHSRM KREVSAHFHE VLRLKDEMLS
210 220 230 240 250
LSLHYSNALQ EKELAASRCR SLQEELYLLK QELQRANMVS SCELELQEQS
260 270 280 290 300
LRTASDQESG DEELNRLKEE NEKLRSLTFS LAEKDILEQS LDEARGSRQE
310 320 330 340 350
LVERIHSLRE RAVAAERQRE QGEGECAAGP GVRAAEGARP GVLREGQCSE
360 370 380 390 400
GDFPEPGGEG LPPQAGVRAD GPGLRAAHTA SPAAGRASGC AQAGSQDQGA
410 420 430 440 450
LSTGEAAAGA DACHLPQRRQ RLQPRQLHRV SALVGPECHV QPRAGGQLPL
460 470 480 490
QQPRAPQPAV PVQAGGRGLR GRTLVFQQLP GDPGGRPGSP AGS
Length:493
Mass (Da):53,962
Last modified:July 11, 2012 - v1
Checksum:i9B854B0D91D07728
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9BXL6CAR14_HUMAN
Caspase recruitment domain-containi...
CARD14 CARMA2
1,004Annotation score:
I3L3F1I3L3F1_HUMAN
Caspase recruitment domain-containi...
CARD14
475Annotation score:
I3L1Z7I3L1Z7_HUMAN
Caspase recruitment domain-containi...
CARD14
70Annotation score:
I3L4Q8I3L4Q8_HUMAN
Caspase recruitment domain-containi...
CARD14
43Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087741 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89589.1
UniGeneiHs.675480
Hs.696253
Hs.735899

Genome annotation databases

EnsembliENST00000575500; ENSP00000460883; ENSG00000141527
UCSCiuc060lbo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087741 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89589.1
UniGeneiHs.675480
Hs.696253
Hs.735899

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiI3L414
PeptideAtlasiI3L414
PRIDEiI3L414

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000575500; ENSP00000460883; ENSG00000141527
UCSCiuc060lbo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000141527.16
HGNCiHGNC:16446 CARD14
OpenTargetsiENSG00000141527
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0708 Eukaryota
COG0194 LUCA
GeneTreeiENSGT00530000063108

Miscellaneous databases

ChiTaRSiCARD14 human

Gene expression databases

BgeeiENSG00000141527 Expressed in 126 organ(s), highest expression level in ectocervix
ExpressionAtlasiI3L414 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI3L414_HUMAN
AccessioniPrimary (citable) accession number: I3L414
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 12, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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