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Protein
Submitted name:

Carbonic anhydrase-related protein 10

Gene

CA10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Carbonic anhydrase-related protein 10Imported
Gene namesi
Name:CA10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000154975.13
HGNCiHGNC:1369 CA10

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000154975

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500367453922 – 276Sequence analysisAdd BLAST255

Proteomic databases

PeptideAtlasiI3L375
PRIDEiI3L375

Expressioni

Gene expression databases

BgeeiENSG00000154975 Expressed in 111 organ(s), highest expression level in cerebellar hemisphere
ExpressionAtlasiI3L375 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliI3L375
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 276Alpha-carbonic anhydraseInterPro annotationAdd BLAST246

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0382 Eukaryota
COG3338 LUCA
GeneTreeiENSGT00920000149072

Family and domain databases

Gene3Di3.10.200.10, 1 hit
InterProiView protein in InterPro
IPR018423 CA10
IPR001148 CA_dom
IPR036398 CA_dom_sf
IPR023561 Carbonic_anhydrase_a-class
PANTHERiPTHR18952 PTHR18952, 1 hit
PTHR18952:SF91 PTHR18952:SF91, 1 hit
PfamiView protein in Pfam
PF00194 Carb_anhydrase, 1 hit
SMARTiView protein in SMART
SM01057 Carb_anhydrase, 1 hit
SUPFAMiSSF51069 SSF51069, 1 hit
PROSITEiView protein in PROSITE
PS51144 ALPHA_CA_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

I3L375-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEIVWEVLFL LQANFIVCIS AQQNSPKIHE GWWAYKEVVQ GSFVPVPSFW
60 70 80 90 100
GLVNSAWNLC SVGKRQSPVN IETSHMIFDP FLTPLRINTG GRKVSGTMYN
110 120 130 140 150
TGRHVSLRLD KEHLVNISGG PMTYSHRLEE IRLHFGSEDS QGSEHLLNGQ
160 170 180 190 200
AFSGEVQLIH YNHELYTNVT EAAKSPNGLV VVSIFIKVSD SSNPFLNRML
210 220 230 240 250
NRDTITRITY KNDAYLLQGL NIEELYPETS SFITYDGSMT IPPCYETASW
260 270
IIMNKPVYIT RMQMHSLRLL SQNQPS
Length:276
Mass (Da):31,358
Last modified:July 11, 2012 - v1
Checksum:i625AA6735BDA5D42
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NS85CAH10_HUMAN
Carbonic anhydrase-related protein ...
CA10 hucep-15, UNQ533/PRO1076
328Annotation score:
I3L0J7I3L0J7_HUMAN
Carbonic anhydrase-related protein ...
CA10
56Annotation score:
I3NI54I3NI54_HUMAN
Carbonic anhydrase-related protein ...
CA10
42Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei276Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002090 Genomic DNA No translation available.
AC004108 Genomic DNA No translation available.
AC005883 Genomic DNA No translation available.
AC006083 Genomic DNA No translation available.
AC016473 Genomic DNA No translation available.
KC877658 Genomic DNA No translation available.
KF456289 Genomic DNA No translation available.
KF511488 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000575181; ENSP00000460238; ENSG00000154975
UCSCiuc060hpm.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002090 Genomic DNA No translation available.
AC004108 Genomic DNA No translation available.
AC005883 Genomic DNA No translation available.
AC006083 Genomic DNA No translation available.
AC016473 Genomic DNA No translation available.
KC877658 Genomic DNA No translation available.
KF456289 Genomic DNA No translation available.
KF511488 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliI3L375
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiI3L375
PRIDEiI3L375

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000575181; ENSP00000460238; ENSG00000154975
UCSCiuc060hpm.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000154975.13
HGNCiHGNC:1369 CA10
OpenTargetsiENSG00000154975
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0382 Eukaryota
COG3338 LUCA
GeneTreeiENSGT00920000149072

Miscellaneous databases

ChiTaRSiCA10 human

Gene expression databases

BgeeiENSG00000154975 Expressed in 111 organ(s), highest expression level in cerebellar hemisphere
ExpressionAtlasiI3L375 baseline and differential

Family and domain databases

Gene3Di3.10.200.10, 1 hit
InterProiView protein in InterPro
IPR018423 CA10
IPR001148 CA_dom
IPR036398 CA_dom_sf
IPR023561 Carbonic_anhydrase_a-class
PANTHERiPTHR18952 PTHR18952, 1 hit
PTHR18952:SF91 PTHR18952:SF91, 1 hit
PfamiView protein in Pfam
PF00194 Carb_anhydrase, 1 hit
SMARTiView protein in SMART
SM01057 Carb_anhydrase, 1 hit
SUPFAMiSSF51069 SSF51069, 1 hit
PROSITEiView protein in PROSITE
PS51144 ALPHA_CA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI3L375_HUMAN
AccessioniPrimary (citable) accession number: I3L375
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 12, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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