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Protein
Submitted name:

Segment polarity protein dishevelled homolog DVL-2

Gene

DVL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processWnt signaling pathwayPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Segment polarity protein dishevelled homolog DVL-2Imported
Gene namesi
Name:DVL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000004975.11
HGNCiHGNC:3086 DVL2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000004975

PTM / Processingi

Proteomic databases

EPDiI3L2W9
MaxQBiI3L2W9
PeptideAtlasiI3L2W9
PRIDEiI3L2W9

Expressioni

Gene expression databases

BgeeiENSG00000004975
ExpressionAtlasiI3L2W9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliI3L2W9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 93DIXInterPro annotationAdd BLAST83
Domaini263 – 335PDZInterPro annotationAdd BLAST73

Phylogenomic databases

eggNOGiKOG3571 Eukaryota
ENOG410Y5G4 LUCA
GeneTreeiENSGT00390000013552

Family and domain databases

Gene3Di3.10.20.380, 1 hit
InterProiView protein in InterPro
IPR003351 Dishevelled_protein_dom
IPR001158 DIX
IPR038207 DIX_dom_sf
IPR015506 Dsh/Dvl-rel
IPR008341 DVL2
IPR001478 PDZ
IPR036034 PDZ_sf
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR10878 PTHR10878, 1 hit
PTHR10878:SF8 PTHR10878:SF8, 1 hit
PfamiView protein in Pfam
PF02377 Dishevelled, 1 hit
PF00778 DIX, 1 hit
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00021 DAX, 1 hit
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50841 DIX, 1 hit
PS50106 PDZ, 1 hit

Sequencei

Sequence statusi: Fragment.

I3L2W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSSTGGGG VGETKVIYHL DEEETPYLVK IPVPAERITL GDFKSVLQRP
60 70 80 90 100
AGAKYFFKSM DQDFGVVKEE ISDDNARLPC FNGRVVSWLV SSDNPQPEMA
110 120 130 140 150
PPVHEPRAEL APPAPPLPPL PPERTSGIGD SRPPSFHPNV SSSHENLEPE
160 170 180 190 200
TETESVVSLR RERPRRRDST GGHRTGGPSR LERHLAGYES SSTLMTSELE
210 220 230 240 250
STSLGDSDEE DTMSRFSSST EQSSASRLLK RHRRRRKQRP PRLERTSSFS
260 270 280 290 300
SVTDSTMSLN IITVTLNMEK YNFLGISIVG QSNERGDGGI YIGSIMKGGA
310 320 330 340 350
VAADGRIEPG DMLLQVNDMN FENMSNDDAV RVLRDIVHKP GPIVLTVAKC
360
WDPSPQAYFT LPR
Length:363
Mass (Da):39,918
Last modified:July 11, 2012 - v1
Checksum:iB336D6CBDAFB0EBA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei363Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120057 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000575756; ENSP00000459991; ENSG00000004975
UCSCiuc060aka.1 human

Similar proteinsi

Entry informationi

Entry nameiI3L2W9_HUMAN
AccessioniPrimary (citable) accession number: I3L2W9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: June 20, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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