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UniProtKB - I3L2C0 (I3L2C0_HUMAN)
Protein
Submitted name:
Active breakpoint cluster region-related protein
Gene
ABR
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- GTPase activator activity Source: InterPro
GO - Biological processi
- positive regulation of GTPase activity Source: InterPro
- signal transduction Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Active breakpoint cluster region-related proteinImported |
Gene namesi | Name:ABRImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:81, ABR |
VEuPathDBi | HostDB:ENSG00000159842 |
Expressioni
Gene expression databases
Bgeei | ENSG00000159842, Expressed in frontal cortex and 241 other tissues |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 34 | DisorderedSequence analysisAdd BLAST | 34 |
Phylogenomic databases
GeneTreei | ENSGT00940000153491 |
HOGENOMi | CLU_1712665_0_0_1 |
Family and domain databases
Gene3Di | 1.10.555.10, 1 hit |
InterProi | View protein in InterPro IPR037769, Abr/Bcr IPR008936, Rho_GTPase_activation_prot |
PANTHERi | PTHR23182, PTHR23182, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 21 potential isoforms that are computationally mapped.Show allAlign All
I3L2C0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDVLPQPDC SPKAGREPLA LEESGSKRPP NTGARLWGRV RNKLLRNKLD
60 70 80 90 100
PQTVETKNWH TDVIEMNGIK VEFSMKFTSR DMSLKRTPSK KQTGVFGVKI
110 120 130 140 150
SVVTKRERSK VPYIVRQCVE EAVRLLRKHH RLNGGGMHMP RWVSRVAGRQ
LSS
Computationally mapped potential isoform sequencesi
There are 21 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ12979 | ABR_HUMAN | Active breakpoint cluster region-re... | ABR | 859 | Annotation score: | ||
A0A1C7CYZ0 | A0A1C7CYZ0_HUMAN | Active breakpoint cluster region-re... | ABR | 871 | Annotation score: | ||
I3L4Y1 | I3L4Y1_HUMAN | Active breakpoint cluster region-re... | ABR | 1,118 | Annotation score: | ||
B7Z683 | B7Z683_HUMAN | Active breakpoint cluster region-re... | ABR | 641 | Annotation score: | ||
A0A0G2JQ41 | A0A0G2JQ41_HUMAN | Active breakpoint cluster region-re... | ABR | 777 | Annotation score: | ||
I3L3W0 | I3L3W0_HUMAN | Active breakpoint cluster region-re... | ABR | 133 | Annotation score: | ||
I3L259 | I3L259_HUMAN | Active breakpoint cluster region-re... | ABR | 86 | Annotation score: | ||
I3L2L3 | I3L2L3_HUMAN | Active breakpoint cluster region-re... | ABR | 88 | Annotation score: | ||
A0A0G2JQB5 | A0A0G2JQB5_HUMAN | Active breakpoint cluster region-re... | ABR | 129 | Annotation score: | ||
I3NI05 | I3NI05_HUMAN | Active breakpoint cluster region-re... | ABR | 191 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC015884 Genomic DNA No translation available. AC016292 Genomic DNA No translation available. AC107911 Genomic DNA No translation available. AC144836 Genomic DNA No translation available. AC212841 Genomic DNA No translation available. AC226497 Genomic DNA No translation available. KF456222 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000572441; ENSP00000459553; ENSG00000159842 ENST00000626654; ENSP00000487341; ENSG00000278741 ENST00000627848; ENSP00000486789; ENSG00000276016 |
UCSCi | uc059zde.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC015884 Genomic DNA No translation available. AC016292 Genomic DNA No translation available. AC107911 Genomic DNA No translation available. AC144836 Genomic DNA No translation available. AC212841 Genomic DNA No translation available. AC226497 Genomic DNA No translation available. KF456222 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
ProteomicsDBi | 46903 |
Protocols and materials databases
Antibodypediai | 22668, 75 antibodies from 19 providers |
Genome annotation databases
Ensembli | ENST00000572441; ENSP00000459553; ENSG00000159842 ENST00000626654; ENSP00000487341; ENSG00000278741 ENST00000627848; ENSP00000486789; ENSG00000276016 |
UCSCi | uc059zde.1, human |
Organism-specific databases
HGNCi | HGNC:81, ABR |
OpenTargetsi | ENSG00000159842 |
VEuPathDBi | HostDB:ENSG00000159842 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153491 |
HOGENOMi | CLU_1712665_0_0_1 |
Miscellaneous databases
ChiTaRSi | ABR, human |
Gene expression databases
Bgeei | ENSG00000159842, Expressed in frontal cortex and 241 other tissues |
Family and domain databases
Gene3Di | 1.10.555.10, 1 hit |
InterProi | View protein in InterPro IPR037769, Abr/Bcr IPR008936, Rho_GTPase_activation_prot |
PANTHERi | PTHR23182, PTHR23182, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | I3L2C0_HUMAN | |
Accessioni | I3L2C0Primary (citable) accession number: I3L2C0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 11, 2012 |
Last sequence update: | July 11, 2012 | |
Last modified: | January 19, 2022 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |