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Protein
Submitted name:

Transcription factor AP-4

Gene

TFAP4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor AP-4Imported
Gene namesi
Name:TFAP4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000090447.11
HGNCiHGNC:11745 TFAP4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000090447

PTM / Processingi

Proteomic databases

EPDiI3L254
MaxQBiI3L254
PeptideAtlasiI3L254
PRIDEiI3L254

Expressioni

Gene expression databases

BgeeiENSG00000090447 Expressed in 210 organ(s), highest expression level in cingulate cortex
ExpressionAtlasiI3L254 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliI3L254
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 39BHLHInterPro annotationAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili39 – 59Sequence analysisAdd BLAST21
Coiled coili88 – 115Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0561 Eukaryota
ENOG4111JPE LUCA
GeneTreeiENSGT00390000015189

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

I3L254-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSINAGFQS LKTLIPHTDG EKLSKAAILQ QTAEYIFSLE QEKTRLLQQN
60 70 80 90 100
TQLKRFIQEL SGSSPKRRRA EDKDEGIGSP DIWEDEKAED LRREMIELRQ
110
QLDKERSVRM MLEEQ
Length:115
Mass (Da):13,462
Last modified:July 11, 2012 - v1
Checksum:i8ACD8115D07BBA56
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q01664TFAP4_HUMAN
Transcription factor AP-4
TFAP4 BHLHC41
338Annotation score:
I3L301I3L301_HUMAN
Transcription factor AP-4
TFAP4
167Annotation score:
I3L4L6I3L4L6_HUMAN
Transcription factor AP-4
TFAP4
44Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei115Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009171 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000572393; ENSP00000459390; ENSG00000090447
UCSCiuc059qcs.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009171 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliI3L254
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiI3L254
MaxQBiI3L254
PeptideAtlasiI3L254
PRIDEiI3L254

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000572393; ENSP00000459390; ENSG00000090447
UCSCiuc059qcs.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000090447.11
HGNCiHGNC:11745 TFAP4
OpenTargetsiENSG00000090447
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0561 Eukaryota
ENOG4111JPE LUCA
GeneTreeiENSGT00390000015189

Gene expression databases

BgeeiENSG00000090447 Expressed in 210 organ(s), highest expression level in cingulate cortex
ExpressionAtlasiI3L254 baseline and differential

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI3L254_HUMAN
AccessioniPrimary (citable) accession number: I3L254
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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