UniProtKB - I3L1C8 (I3L1C8_HUMAN)
Protein
Submitted name:
Brain-specific angiogenesis inhibitor 1-associated protein 2
Gene
BAIAP2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- cytoskeletal adaptor activity Source: InterPro
GO - Biological processi
- plasma membrane organization Source: InterPro
- regulation of actin cytoskeleton organization Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Brain-specific angiogenesis inhibitor 1-associated protein 2Imported |
Gene namesi | Name:BAIAP2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:947 BAIAP2 |
PTM / Processingi
Proteomic databases
jPOSTi | I3L1C8 |
MaxQBi | I3L1C8 |
PeptideAtlasi | I3L1C8 |
PRIDEi | I3L1C8 |
ProteomicsDBi | 46602 |
Expressioni
Gene expression databases
Bgeei | ENSG00000175866 Expressed in 194 organ(s), highest expression level in Brodmann (1909) area 10 |
ExpressionAtlasi | I3L1C8 baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 180 | IMDInterPro annotationAdd BLAST | 180 |
Phylogenomic databases
eggNOGi | ENOG410IKMM Eukaryota ENOG41110CD LUCA |
GeneTreei | ENSGT00940000153560 |
Family and domain databases
Gene3Di | 1.20.1270.60, 1 hit |
InterProi | View protein in InterPro IPR027267 AH/BAR_dom_sf IPR013606 I-BAR_dom IPR030128 IRSp53 IPR027681 IRSp53/IRTKS/Pinkbar |
PANTHERi | PTHR14206 PTHR14206, 1 hit PTHR14206:SF3 PTHR14206:SF3, 1 hit |
Pfami | View protein in Pfam PF08397 IMD, 1 hit |
SUPFAMi | SSF103657 SSF103657, 1 hit |
PROSITEi | View protein in PROSITE PS51338 IMD, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All
I3L1C8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGELASESQG SKELGDVLFQ MAEVHRQIQN QLEEMLKSFH NELLTQLEQK
60 70 80 90 100
VELDSRYLSA ALKKYQTEQR SKGDALDKCQ AELKKLRKKS QGSKNPQKYS
110 120 130 140 150
DKELQYIDAI SNKQGELENY VSDGYKTALT EERRRFCFLV EKQCAVAKNS
160 170 180
AAYHSKGKEL LAQKLPLWQQ ACADPSKIPE
Computationally mapped potential isoform sequencesi
There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UQB8 | BAIP2_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 552 | Annotation score: | ||
I3L4C2 | I3L4C2_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 553 | Annotation score: | ||
B4DWA1 | B4DWA1_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 375 | Annotation score: | ||
I3L3C6 | I3L3C6_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 216 | Annotation score: | ||
I3L0Y9 | I3L0Y9_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 130 | Annotation score: | ||
I3L526 | I3L526_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 114 | Annotation score: | ||
I3L2M4 | I3L2M4_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 234 | Annotation score: | ||
I3L0M4 | I3L0M4_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 140 | Annotation score: | ||
I3L113 | I3L113_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 79 | Annotation score: | ||
I3L125 | I3L125_HUMAN | Brain-specific angiogenesis inhibit... | BAIAP2 | 135 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 180 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC115099 Genomic DNA No translation available. AC127496 Genomic DNA No translation available. KC877672 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000573677; ENSP00000458735; ENSG00000175866 |
UCSCi | uc060lgk.1 human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC115099 Genomic DNA No translation available. AC127496 Genomic DNA No translation available. KC877672 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
jPOSTi | I3L1C8 |
MaxQBi | I3L1C8 |
PeptideAtlasi | I3L1C8 |
PRIDEi | I3L1C8 |
ProteomicsDBi | 46602 |
Genome annotation databases
Ensembli | ENST00000573677; ENSP00000458735; ENSG00000175866 |
UCSCi | uc060lgk.1 human |
Organism-specific databases
HGNCi | HGNC:947 BAIAP2 |
OpenTargetsi | ENSG00000175866 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG410IKMM Eukaryota ENOG41110CD LUCA |
GeneTreei | ENSGT00940000153560 |
Miscellaneous databases
ChiTaRSi | BAIAP2 human |
Gene expression databases
Bgeei | ENSG00000175866 Expressed in 194 organ(s), highest expression level in Brodmann (1909) area 10 |
ExpressionAtlasi | I3L1C8 baseline and differential |
Family and domain databases
Gene3Di | 1.20.1270.60, 1 hit |
InterProi | View protein in InterPro IPR027267 AH/BAR_dom_sf IPR013606 I-BAR_dom IPR030128 IRSp53 IPR027681 IRSp53/IRTKS/Pinkbar |
PANTHERi | PTHR14206 PTHR14206, 1 hit PTHR14206:SF3 PTHR14206:SF3, 1 hit |
Pfami | View protein in Pfam PF08397 IMD, 1 hit |
SUPFAMi | SSF103657 SSF103657, 1 hit |
PROSITEi | View protein in PROSITE PS51338 IMD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | I3L1C8_HUMAN | |
Accessioni | I3L1C8Primary (citable) accession number: I3L1C8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 11, 2012 |
Last sequence update: | July 11, 2012 | |
Last modified: | July 31, 2019 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |