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Protein
Submitted name:

NF-kappa-B inhibitor beta

Gene

NFKBIB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NF-kappa-B inhibitor betaImported
Gene namesi
Name:NFKBIBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000104825.16
HGNCiHGNC:7798 NFKBIB

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104825

PTM / Processingi

Proteomic databases

MaxQBiI3L1A4
PeptideAtlasiI3L1A4
PRIDEiI3L1A4

Expressioni

Gene expression databases

BgeeiENSG00000104825 Expressed in 194 organ(s), highest expression level in right testis
ExpressionAtlasiI3L1A4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliI3L1A4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 72ANK_REP_REGIONInterPro annotationAdd BLAST56
Repeati17 – 49ANKPROSITE-ProRule annotationAdd BLAST33
Domaini130 – 149ANK_REP_REGIONInterPro annotationAdd BLAST20
Repeati130 – 149ANKPROSITE-ProRule annotationAdd BLAST20

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00550000074527

Family and domain databases

CDDicd00204 ANK, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 2 hits
PS50088 ANK_REPEAT, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

I3L1A4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNGFSAGTEY MDLQNDLGQT ALHLAAILGE TSTVEKLYAA GAGLCVAERR
60 70 80 90 100
GHTALHLACR VGAHACARAL LQPRPRRPRE APDTYLAQGP DRTPDTNHTP
110 120 130 140
VALYPDSDLE KEEEESEEDW KLQLEAENYE GHTPLHVAVI HKDVEMVRL
Length:149
Mass (Da):16,451
Last modified:July 11, 2012 - v1
Checksum:i9AA8DC7A3793786C
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q15653IKBB_HUMAN
NF-kappa-B inhibitor beta
NFKBIB IKBB, TRIP9
356Annotation score:
G5E9C2G5E9C2_HUMAN
NF-kappa-B inhibitor beta
NFKBIB
270Annotation score:
I3L4X3I3L4X3_HUMAN
NF-kappa-B inhibitor beta
NFKBIB
233Annotation score:
H0YFH0H0YFH0_HUMAN
NF-kappa-B inhibitor beta
NFKBIB
65Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei149Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011455 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000575359; ENSP00000458685; ENSG00000104825
UCSCiuc060yhm.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011455 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliI3L1A4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiI3L1A4
PeptideAtlasiI3L1A4
PRIDEiI3L1A4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000575359; ENSP00000458685; ENSG00000104825
UCSCiuc060yhm.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000104825.16
HGNCiHGNC:7798 NFKBIB
OpenTargetsiENSG00000104825
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00550000074527

Miscellaneous databases

ChiTaRSiNFKBIB human

Gene expression databases

BgeeiENSG00000104825 Expressed in 194 organ(s), highest expression level in right testis
ExpressionAtlasiI3L1A4 baseline and differential

Family and domain databases

CDDicd00204 ANK, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 2 hits
PS50088 ANK_REPEAT, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiI3L1A4_HUMAN
AccessioniPrimary (citable) accession number: I3L1A4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 12, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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