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Protein
Submitted name:

Lysine-specific demethylase 6B

Gene

KDM6B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Lysine-specific demethylase 6BImported
Gene namesi
Name:KDM6BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000132510.10
HGNCiHGNC:29012 KDM6B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132510

PTM / Processingi

Proteomic databases

PeptideAtlasiI3L0Z0
PRIDEiI3L0Z0

Expressioni

Gene expression databases

BgeeiENSG00000132510 Expressed in 211 organ(s), highest expression level in blood
ExpressionAtlasiI3L0Z0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliI3L0Z0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00410000025758

Family and domain databases

InterProiView protein in InterPro
IPR029518 KDM6B
PANTHERiPTHR14017:SF5 PTHR14017:SF5, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

I3L0Z0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHRAVDPPGA RAAREAFALG GLSCAGAWSS CPPHPPPRSA WLPGGRCSAS
60 70 80 90 100
IGQPPLPAPL PPSHGSSSGH PSKPYYAPGA PTPRPLHGKL ESLHGCVQAL
110 120 130 140 150
LREPAQPGLW EQLGQLYESE HDSEEATRCY HSALRYGGSF AELGPRIGRL
160 170 180 190 200
QQAQLWNFHT GSCQHRAKVL PPLEQVWNLL HLEHKRNYGA KRGGPPVKRA
210 220 230 240 250
AEPPVVQPVP PAALSGPSGE EGLSPGGKRR RGCNSEQEQR HSLPHPYPYP
260 270 280 290 300
APAYTAHPPG HRLVPAAPPG PGPRPPGAES HGCLPATRPP GSDLRESRVQ
310 320 330 340 350
RSRMDSSVSP AATTACVPYA PSRPPGLPGT TTSSSSSSSS NTGLRGVEPN
360
PGIPGADHYQ T
Length:361
Mass (Da):38,035
Last modified:October 5, 2016 - v8
Checksum:i248884310F4C7FAD
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15054KDM6B_HUMAN
Lysine-specific demethylase 6B
KDM6B JMJD3, KIAA0346
1,643Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei361Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104581 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000570632; ENSP00000458445; ENSG00000132510
UCSCiuc060avr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104581 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliI3L0Z0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiI3L0Z0
PRIDEiI3L0Z0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000570632; ENSP00000458445; ENSG00000132510
UCSCiuc060avr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132510.10
HGNCiHGNC:29012 KDM6B
OpenTargetsiENSG00000132510
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00410000025758

Miscellaneous databases

ChiTaRSiKDM6B human

Gene expression databases

BgeeiENSG00000132510 Expressed in 211 organ(s), highest expression level in blood
ExpressionAtlasiI3L0Z0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR029518 KDM6B
PANTHERiPTHR14017:SF5 PTHR14017:SF5, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiI3L0Z0_HUMAN
AccessioniPrimary (citable) accession number: I3L0Z0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 45 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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