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Protein
Submitted name:

Coiled-coil domain-containing protein 137

Gene

CCDC137

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Coiled-coil domain-containing protein 137Imported
Gene namesi
Name:CCDC137Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000185298.12
HGNCiHGNC:33451 CCDC137

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185298

PTM / Processingi

Proteomic databases

EPDiI3L0U5
MaxQBiI3L0U5
PeptideAtlasiI3L0U5
PRIDEiI3L0U5

Expressioni

Gene expression databases

BgeeiENSG00000185298 Expressed in 173 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiI3L0U5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliI3L0U5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili186 – 206Sequence analysisAdd BLAST21
Coiled coili257 – 280Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IENS Eukaryota
ENOG4111TSW LUCA
GeneTreeiENSGT00390000004169
OMAiIPVRKHH
OrthoDBiEOG091G0R9C

Family and domain databases

InterProiView protein in InterPro
IPR026680 CCDC137
PANTHERiPTHR21838 PTHR21838, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

I3L0U5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGAGRGAAV SRVQAGPGSP RRARGRQQVQ PLGKQRPAPW PGLRSKEKKK
60 70 80 90 100
VNCKPKNQDE QEIPFRLREI MRSRQEMKNP ISNKKRKKAA VLQWTSVTAQ
110 120 130 140 150
VTFRKTLEKE AKGEEPDIAV PKFKQRKGES DGAYIHRMQQ EAQHVLFLSK
160 170 180 190 200
NQAIRQPEVQ AAPKEKSEQK KAKKAFQKRR LDKVRRKKEE KAADRLEQEL
210 220 230 240 250
LRDTVKFGEV VLQPPELTAR PQRSVSKDQP GRRSQMLRML LSPGGVSQPL
260 270 280 290
TASLARQRIV EEERERAVQA YRALKQRQQQ LHGERPHLTS RK
Length:292
Mass (Da):33,525
Last modified:July 11, 2012 - v1
Checksum:iC498EADE75470735
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6PK04CC137_HUMAN
Coiled-coil domain-containing prote...
CCDC137 cPERP-B
289Annotation score:
I3L4F6I3L4F6_HUMAN
Coiled-coil domain-containing prote...
CCDC137
44Annotation score:
I3L385I3L385_HUMAN
Coiled-coil domain-containing prote...
CCDC137
61Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei292Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139530 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000574107; ENSP00000458350; ENSG00000185298
UCSCiuc060lls.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139530 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliI3L0U5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiI3L0U5
MaxQBiI3L0U5
PeptideAtlasiI3L0U5
PRIDEiI3L0U5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000574107; ENSP00000458350; ENSG00000185298
UCSCiuc060lls.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000185298.12
HGNCiHGNC:33451 CCDC137
OpenTargetsiENSG00000185298
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IENS Eukaryota
ENOG4111TSW LUCA
GeneTreeiENSGT00390000004169
OMAiIPVRKHH
OrthoDBiEOG091G0R9C

Miscellaneous databases

ChiTaRSiCCDC137 human

Gene expression databases

BgeeiENSG00000185298 Expressed in 173 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiI3L0U5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR026680 CCDC137
PANTHERiPTHR21838 PTHR21838, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI3L0U5_HUMAN
AccessioniPrimary (citable) accession number: I3L0U5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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