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Protein
Submitted name:

BRCA1 interacting protein C-terminal helicase 1

Gene
N/A
Organism
Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
BRCA1 interacting protein C-terminal helicase 1Imported
OrganismiOreochromis niloticus (Nile tilapia) (Tilapia nilotica)Imported
Taxonomic identifieri8128 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaCichlomorphaeCichliformesCichlidaeAfrican cichlidsPseudocrenilabrinaeOreochrominiOreochromis
Proteomesi
  • UP000005207 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi8128.ENSONIP00000013157

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 449Helicase ATP-bindingInterPro annotationAdd BLAST439

Phylogenomic databases

eggNOGiKOG1132 Eukaryota
COG1199 LUCA
GeneTreeiENSGT00530000063199
InParanoidiI3JWB2
OMAiTNNDMNQ
OrthoDBiEOG091G00LK
TreeFamiTF329449

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF13307 Helicase_C_2, 1 hit
SMARTiView protein in SMART
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 6 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS51193 HELICASE_ATP_BIND_2, 1 hit

Sequencei

Sequence statusi: Complete.

I3JWB2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSSPVEYTI GGVKIHFPCK AYPSQLAMMN LIVRGLNTGQ YCLLESPTGS
60 70 80 90 100
GKSLALLCSA LGWQHAQFGK PGGSTGPDKS QKSDSPTSCK CGCHSKSSRN
110 120 130 140 150
KATAGDSHAV VDLTVSPSKD TAQPSTSAQE PKEERRKQSL ASRLSEKFQK
160 170 180 190 200
SLSSDCAKDD DFQQDRKRIR TAENTSRKRQ RLEKGVVFTD DKAAESTSVP
210 220 230 240 250
CSVPINAIFL DRSILYILSN CDAPESCSQC PCGSTEDAVK DKEKDGRKKT
260 270 280 290 300
PKIFFGTRTH KQITQITHEL KRTVYSGVPM TILSSRDHTC VNPDVVPHTN
310 320 330 340 350
RNERCKDLLE AKDGRSCRYY HGVQRMRDQN TLQHVHGLRA AWDIEDLVTL
360 370 380 390 400
GKRLRSCSYF AARELMQSAW IIFCPYNYLL DPMIRESMEI DLEGQILVLD
410 420 430 440 450
EAHNIEDCAR ESASYTLDYK SLLMSRDELD SMVNNNIRRS KHELLRGFCY
460 470 480 490 500
SLINWIQESQ SLMSERGYET AGKVWSGKEI VGIFHTLGIT ADTFNILKQN
510 520 530 540 550
LAAVLEKEEH AGVVNGREDV VQIPTISPPT ATVLKNLFMV LDFLFRDSCR
560 570 580 590 600
FADDYRVALQ KSYAWTNQVP PDVPNAQGFI VRPRGRRQTV RVKTEVLTLS
610 620 630 640 650
FWCLNPAVAF SDLSGSVHSI VLTSGTLSPM DSFSSELGVK FSIQLEANHV
660 670 680 690 700
INKSQVWVGT VGAGPQGRKL CATFQNAETY AFQDEVGGLL LHVCQVMAKG
710 720 730 740 750
VLCFLPSYKM LDKLRDRWTK TGLWDKLEQQ KTVITEPRGG GGKGDFDELL
760 770 780 790 800
HTYYSAIKYC EEKDGALLIA VCRGKVSEGL DFTDDNARAV VAVGIPFPNI
810 820 830 840 850
KDLQVELKMK YNDLHSKSRG LLPGSRWYEI QAYRALNQAL GRCIRHRNDW
860 870 880 890 900
GALVLVDDRY RNNPNKYITG LSKWVRQLVQ HHSTFSDAMQ SLVAFSQVQK

KMDGAP
Length:906
Mass (Da):101,389
Last modified:July 11, 2012 - v1
Checksum:i70B66AB9F8C67F33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AERX01031533 Genomic DNA No translation available.
AERX01031534 Genomic DNA No translation available.
AERX01031535 Genomic DNA No translation available.
AERX01031536 Genomic DNA No translation available.
AERX01031537 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSONIT00000013167; ENSONIP00000013157; ENSONIG00000010466

Similar proteinsi

Entry informationi

Entry nameiI3JWB2_ORENI
AccessioniPrimary (citable) accession number: I3JWB2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: May 23, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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