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Protein
Submitted name:

Uncharacterized protein

Gene

SLC25A12 (1 of many)

Organism
Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi171 – 182PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotationSAAS annotation
LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SLC25A12 (1 of many)Imported
OrganismiOreochromis niloticus (Nile tilapia) (Tilapia nilotica)Imported
Taxonomic identifieri8128 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaCichlomorphaeCichliformesCichlidaeAfrican cichlidsPseudocrenilabrinaeOreochrominiOreochromis
Proteomesi
  • UP000005207 Componenti: Unplaced

Subcellular locationi

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi8128.ENSONIP00000013052

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 81EF-handInterPro annotationAdd BLAST29
Domaini87 – 122EF-handInterPro annotationAdd BLAST36
Domaini158 – 193EF-handInterPro annotationAdd BLAST36
Repeati325 – 417SolcarPROSITE-ProRule annotationAdd BLAST93
Repeati425 – 509SolcarPROSITE-ProRule annotationAdd BLAST85
Repeati517 – 605SolcarPROSITE-ProRule annotationAdd BLAST89

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0751 Eukaryota
ENOG410XNRM LUCA
GeneTreeiENSGT00530000062944
InParanoidiI3JW07
OMAiMQNQRGT
OrthoDBiEOG091G08GT
TreeFamiTF313209

Family and domain databases

Gene3Di1.50.40.10, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF13833 EF-hand_8, 1 hit
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 3 hits
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

I3JW07-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVKVQSTKR GDPSELKAIF QQYASVEGKD GERFMTPGDF VQKYLGLHTQ
60 70 80 90 100
IHHNPKTVQV IAAVADTTKD GLISFQEFLA FESVLCAPDA LFIVAFQLFD
110 120 130 140 150
KSGTGDISFE NVQDIFSQTT VHHHIPFNWN CEFIRLHFGH DRKKHLNYLE
160 170 180 190 200
FTQFLQELQL EHARQAFAQK DKDKNGVISA LDFSDIMSTI RHHMLTPFVE
210 220 230 240 250
ENLVSAAGGS TSHMVSFSYF NAFNSLLNNM ELIRKIYSTL AGTRKDTLVT
260 270 280 290 300
KEEFVHAANK FGQITPMEID ILYQLSGLHS PSGRLNLADI DRIAPLEEGC
310 320 330 340 350
LPYHLAESQK QAHGDGSRSV WLQIAESAYR FTLGSIAGAT GATAVYPIDL
360 370 380 390 400
VKTRMQNQRS TGSFVGELMY KNSFDCAKKV LRYEGFFGFY RGLLPQLIGV
410 420 430 440 450
APEKAIKLTV NDFVRDKFTE KDDTIPLFAE IMAGGCAGAS QVIFTNPLEI
460 470 480 490 500
VKIRLQVAGE ITTGPRVSAL SVVRDLGFFG LYKGAKACFL RDIPFSAIYF
510 520 530 540 550
PVYAHTKTQL ADEQGRLGAL QLLTAGAIAG IPAASLVTPA DVIKTRLQVA
560 570 580 590 600
ARAGQTTYSG VMDCFRKILK EEGFRALWKG AGARMCRSSP QFGVTLVTYE
610 620 630 640 650
LLQRWFYVDF GGHRPSGSEP KPKSRISELP PINVDHIGGY RLAAATFAGV
660 670
ENKFGLHLPK FKSSGVASIH HPAQAP
Length:676
Mass (Da):74,727
Last modified:July 11, 2012 - v1
Checksum:i17AA15B26E0209B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AERX01001287 Genomic DNA No translation available.
RefSeqiXP_003438251.1, XM_003438203.4

Genome annotation databases

EnsembliENSONIT00000013062; ENSONIP00000013052; ENSONIG00000010386
GeneIDi100700247

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AERX01001287 Genomic DNA No translation available.
RefSeqiXP_003438251.1, XM_003438203.4

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8128.ENSONIP00000013052

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSONIT00000013062; ENSONIP00000013052; ENSONIG00000010386
GeneIDi100700247

Phylogenomic databases

eggNOGiKOG0751 Eukaryota
ENOG410XNRM LUCA
GeneTreeiENSGT00530000062944
InParanoidiI3JW07
OMAiMQNQRGT
OrthoDBiEOG091G08GT
TreeFamiTF313209

Family and domain databases

Gene3Di1.50.40.10, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF13833 EF-hand_8, 1 hit
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 3 hits
PS50920 SOLCAR, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiI3JW07_ORENI
AccessioniPrimary (citable) accession number: I3JW07
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: October 10, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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