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Protein
Submitted name:

Nuclear receptor subfamily 3, group C, member 2

Gene

nr3c2

Organism
Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi614 – 689Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3, group C, member 2Imported
Gene namesi
Name:nr3c2Imported
OrganismiOreochromis niloticus (Nile tilapia) (Tilapia nilotica)Imported
Taxonomic identifieri8128 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaCichlomorphaeCichliformesCichlidaeAfrican cichlidsPseudocrenilabrinaeOreochrominiOreochromis
Proteomesi
  • UP000005207 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi8128.ENSONIP00000012611

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini614 – 689Nuclear receptorInterPro annotationAdd BLAST76
Domaini743 – 974NR LBDInterPro annotationAdd BLAST232

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
InParanoidiI3JUR6
OMAiSKICLVC
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

I3JUR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKRYQSFF DGKDTENRWP QVPGTMEYCC STEDSSLTGS DILMDIVNVN
60 70 80 90 100
CPAGSPATDC KDNNTKKQEQ PMLQLSQNQP FVLPHFNNSL LGHKQEMDSK
110 120 130 140 150
ELSKTVAESM GLYMNAAREA DFAFNQQGAN TSPGKLYPAC GRPLEENQCG
160 170 180 190 200
PTKSPKLKPF GFQQPSATPR ECTAGTPVSS ASMLASSLSC SPQTSSAISS
210 220 230 240 250
PGGSNNMVSS TTSPPTCFAP LCSSVSSPVS QTSCAATLAN IKRRNSVTCS
260 270 280 290 300
PVESSTVGSP PLTSPLNVMR SPMSSPQSMS SVRSPPSCST TCNIRSSVSS
310 320 330 340 350
PTAGSCSGNT TNNCNTAMPS ISSPATAGTM TVSSPQNPSS AGFPVSSPAD
360 370 380 390 400
GLGLVQNDTN SPEAAGLTRE TDFKNFEFPK VEMVDGEVFN VGLDQMGMVK
410 420 430 440 450
YIKNEPGTDF RSMCLGSSKC NASSTPFITQ IKSEPNKSEG CMNHQPYGEQ
460 470 480 490 500
SPSIGLFPAS ETTYLSLRNN IDEYSLSGIL GPPVSSVNGN YESDVFSNNV
510 520 530 540 550
LSKGVKQEST DGSYYQENNS MSTSAIVGVN SGGHSFHYQI GAQGTMSFTR
560 570 580 590 600
HDMRDQTNPL LNLISPVTAL MESWKSHPGM SQGSLAARGE GYPGQNCISD
610 620 630 640 650
GMSSSPLRQP SSTAKVCLVC GDEASGCHYG VVTCGSCKVF FKRAVEGQHN
660 670 680 690 700
YLCAGRNDCI IDKIRRKNCP ACRVRKCLQA GMNLGARKSK KLKLKGVSED
710 720 730 740 750
LQGSKDGQTA TGGAGGYLSS EKELNASAAN ALVPHRPGVV TPFLPPSICS
760 770 780 790 800
VLELIEPEEV YSGYDNTQPD TTDHLLSSLN RLAGKQMVRM VKWAKVLPGF
810 820 830 840 850
RSLPIEDQIT LIQYSWMCLS SFCLSWRSYK HTNGQMLYFA PDLIFNEERM
860 870 880 890 900
QQSAMYDLCL GMRQVSQEFV RLQLTYDEFL SMKVLLLLST VPKEGLKNQA
910 920 930 940 950
AFEEMRVNYI KELRRSVGKA TNNSGQTWQR FFQLTKLLDA MHDLVGNLLD
960 970 980 990
FCFYTFRESQ ALKVEFPEML VEIISDQIPK VESGLTHTIY FHKK
Length:994
Mass (Da):107,815
Last modified:July 11, 2012 - v1
Checksum:i039A1E5944EAA3F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AERX01022612 Genomic DNA No translation available.
AERX01022613 Genomic DNA No translation available.
RefSeqiXP_003449722.1, XM_003449674.4

Genome annotation databases

EnsembliENSONIT00000012621; ENSONIP00000012611; ENSONIG00000010029
GeneIDi100712208

Similar proteinsi

Entry informationi

Entry nameiI3JUR6_ORENI
AccessioniPrimary (citable) accession number: I3JUR6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: May 23, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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