UniProtKB - I3IT91 (I3IT91_DANRE)
Protein
Submitted name:
Paired box 10
Gene
pax10
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- anatomical structure development Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
- retina development in camera-type eye Source: ZFIN
Keywordsi
Molecular function | DNA-bindingUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Paired box 10Imported |
Gene namesi | Name:pax10Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-081022-10, pax10 |
Subcellular locationi
Nucleus
- Nucleus UniRule annotationARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusUniRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSDARG00000053364, Expressed in retina and 16 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 72 – 132 | HomeoboxInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 131 – 179 | DisorderedSequence analysisAdd BLAST | 49 | |
Regioni | 219 – 240 | DisorderedSequence analysisAdd BLAST | 22 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 140 – 179 | PolarSequence analysisAdd BLAST | 40 |
Sequence similaritiesi
Belongs to the paired homeobox family.ARBA annotation
Keywords - Domaini
HomeoboxUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG0849, Eukaryota |
GeneTreei | ENSGT00940000155391 |
InParanoidi | I3IT91 |
OMAi | GQYWTRL |
OrthoDBi | 1204183at2759 |
TreeFami | TF320146 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR043565, PAX_fam |
PANTHERi | PTHR45636, PTHR45636, 2 hits |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
I3IT91-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MYDNLTMLNL QNSSNWSGPN NWYHPADTIT PQHGTDGCVE DLNVQMAGAG
60 70 80 90 100
EGVVQGERDE VDDSQLHLQL KRKLQRNRTS FTQEQIDALE KEFERTHYPD
110 120 130 140 150
VFARERLAAK IDLPEARIQV WFSNRRAKWR REEKLRNQRR SGSSSSCSQT
160 170 180 190 200
HTPLSTSFNS PVYHSHHSNS SGSMHSRSDS SLSGYSSLSV FSSMQSLPSQ
210 220 230 240 250
STPTYSCMLP PSPSALPPLS RKFDSSYTSP HLPPPPTASA NTGFFAGVSA
260 270
AGQTAVQGGD QELGQGLSQY WTRLQ
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketI3ITD8 | I3ITD8_DANRE | Paired box 10 | pax10 pax6l | 236 | Annotation score: | ||
V5ZE41 | V5ZE41_DANRE | Paired box 10 | pax10 | 276 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FP236454 Genomic DNA No translation available. |
RefSeqi | XP_005164130.1, XM_005164073.3 |
Genome annotation databases
Ensembli | ENSDART00000151608; ENSDARP00000126153; ENSDARG00000053364 ENSDART00000165638; ENSDARP00000140457; ENSDARG00000053364 |
GeneIDi | 100192208 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FP236454 Genomic DNA No translation available. |
RefSeqi | XP_005164130.1, XM_005164073.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000126153 |
Genome annotation databases
Ensembli | ENSDART00000151608; ENSDARP00000126153; ENSDARG00000053364 ENSDART00000165638; ENSDARP00000140457; ENSDARG00000053364 |
GeneIDi | 100192208 |
Organism-specific databases
CTDi | 100192208 |
ZFINi | ZDB-GENE-081022-10, pax10 |
Phylogenomic databases
eggNOGi | KOG0849, Eukaryota |
GeneTreei | ENSGT00940000155391 |
InParanoidi | I3IT91 |
OMAi | GQYWTRL |
OrthoDBi | 1204183at2759 |
TreeFami | TF320146 |
Gene expression databases
Bgeei | ENSDARG00000053364, Expressed in retina and 16 other tissues |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR043565, PAX_fam |
PANTHERi | PTHR45636, PTHR45636, 2 hits |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | I3IT91_DANRE | |
Accessioni | I3IT91Primary (citable) accession number: I3IT91 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 11, 2012 |
Last sequence update: | July 11, 2012 | |
Last modified: | April 7, 2021 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |