UniProtKB - I3IS91 (I3IS91_DANRE)
Protein
Submitted name:
CD109 molecule
Gene
cd109
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- endopeptidase inhibitor activity Source: InterPro
Enzyme and pathway databases
Reactomei | R-DRE-114608, Platelet degranulation |
Names & Taxonomyi
Protein namesi | Submitted name: CD109 moleculeImported |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-120215-253, cd109 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5003671380 | 19 – 1337 | Sequence analysisAdd BLAST | 1319 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000060609, Expressed in gastrula and 12 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 503 – 633 | A2M_N_2InterPro annotationAdd BLAST | 131 | |
Domaini | 727 – 817 | A2MInterPro annotationAdd BLAST | 91 |
Keywords - Domaini
SignalSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155926 |
HOGENOMi | CLU_001634_5_3_1 |
OMAi | EIKLFWS |
Family and domain databases
CDDi | cd02897, A2M_2, 1 hit |
Gene3Di | 2.60.40.10, 2 hits 2.60.40.690, 1 hit |
InterProi | View protein in InterPro IPR036595, A-macroglobulin_rcpt-bd_sf IPR011625, A2M_N_BRD IPR041813, A2M_TED IPR011626, Alpha-macroglobulin_TED IPR013783, Ig-like_fold IPR001599, Macroglobln_a2 IPR019742, MacrogloblnA2_CS IPR002890, MG2 IPR041555, MG3 IPR008930, Terpenoid_cyclase/PrenylTrfase |
Pfami | View protein in Pfam PF00207, A2M, 1 hit PF07703, A2M_BRD, 1 hit PF01835, MG2, 1 hit PF17791, MG3, 1 hit PF07678, TED_complement, 1 hit |
SMARTi | View protein in SMART SM01360, A2M, 1 hit SM01359, A2M_N_2, 1 hit |
SUPFAMi | SSF48239, SSF48239, 1 hit |
PROSITEi | View protein in PROSITE PS00477, ALPHA_2_MACROGLOBULIN, 1 hit |
i Sequence
Sequence statusi: Complete.
I3IS91-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEWLQFFGIL VCSLVCRGAM VTSSARQNLS YLISVSEVLR CGVPTTLSVT
60 70 80 90 100
VLSDYPINVT ARLTHGKTSV AQTQSTVPAG SSRLLSLPPV FYDDMTYWYP
110 120 130 140 150
YQLNVEGFSG THLVFSNSTS MVFSPRCMSI FIQTDKNYYQ PGQTVKFRVV
160 170 180 190 200
SVTPDGKPYS GRTDIFIRDP RGNMIRQWLA VDSFLGVISK ELNISQNPPL
210 220 230 240 250
GSWKITAGVN DVIHERAFTV DYYVLPRFEV KLDVPSVLYC EDTLMGTVTA
260 270 280 290 300
KYFYGKPVSG FMDVRFVHGF NGIEMRYDHT EMIEGSAEIT FDMKDFSTRF
310 320 330 340 350
NDYSYSYYDG YRPIEFIDVN VNITESATGL MYNSSARVSI VTEKYKLEFL
360 370 380 390 400
QYPHIVKPSM TFTAKLKLSL YDQRPLSAED QIESVYLAVT QHKLSPWTWM
410 420 430 440 450
WSDGGPLGPR MMNNTPSTSF PPNSDGGPLG PHMMNSTPPT SFTPIYDLPV
460 470 480 490 500
QNIELPVTAD GLMSFQIHLS DSVATLDLEA RFKDTVQHLQ LYRSYSSPSK
510 520 530 540 550
SYIQLHRDSE PQVGRSLNFT LESSFNLTKI HYLVTSRAGV VDAGTVQSSS
560 570 580 590 600
FSLNTDHLWA PQACVMVYYT LPDGEIVNDA LHVSFTKVLR NTVSVRWSQD
610 620 630 640 650
RAEPAESVSL SVSVSEPGSV LGILVVDKAT LNSAEDNGLS EKTVLEEFLS
660 670 680 690 700
YSREMTHTDN RGMKMGDPYS VFTACGVTVL TDARLNQEMA TNQEMFPMFP
710 720 730 740 750
GEEGLFMTAM PDSSIQEPRQ RKDFPETWIW LDANVSDSAS AVFSLTVPDS
760 770 780 790 800
LTSWAAFAII MSENLGLGIS APAELTVFRD FFMSLDLPAF LIRGELLLLE
810 820 830 840 850
VNLFNYMDVD LEVIVVVAES GMFEFVSTDS ADFSVANVRK VLVLSQNFTM
860 870 880 890 900
LLFPIKATTL GEIPISVKAT SVYSSDWLYK TVLVKPEGLQ QSFTQTLFLE
910 920 930 940 950
FLLQQHTLSR KMTFSFPADV VPNSQRASVS AVGDILGPSI GNLDSLIEMP
960 970 980 990 1000
YGCGEQNMIH FAPNTYVLQY LKSTKQAEEQ TRRKAMSYMM EAYERELSYQ
1010 1020 1030 1040 1050
RVDGSFSAFG DSDESGSTWL SAFVLRCFLQ ARDFISIEPL VMERTAFWLV
1060 1070 1080 1090 1100
AHQESDGSFR EPGQVIHTEL QGGLDGSVSL TAYVLIALLE DAKYESTHKD
1110 1120 1130 1140 1150
SVSLALSFLT SRLAQGISSN YSLSLVAYAL SLAKSSAAPS ALTTLLNRAL
1160 1170 1180 1190 1200
VIDGVPTWRS PGSVLYDSWQ PRSADIEIAA YVLLTMHSLR LMDEGFALMK
1210 1220 1230 1240 1250
WLSQQRNHLG GYGSTQDTVM ALHALSVYAT FSSAESMDLT IRVNEGSGTV
1260 1270 1280 1290 1300
ATFSIDKSNY LLQQSHDLPI ESKDGVDIEV EAEGTGFALF QLTVFYNVMN
1310 1320 1330
VRRSLRRRDI HTDEAFYLYV DIMDKEEYHV NLYTCFR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU525921 Genomic DNA No translation available. CU855808 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000151435; ENSDARP00000125759; ENSDARG00000060609 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU525921 Genomic DNA No translation available. CU855808 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000151435; ENSDARP00000125759; ENSDARG00000060609 |
Organism-specific databases
ZFINi | ZDB-GENE-120215-253, cd109 |
Phylogenomic databases
GeneTreei | ENSGT00940000155926 |
HOGENOMi | CLU_001634_5_3_1 |
OMAi | EIKLFWS |
Enzyme and pathway databases
Reactomei | R-DRE-114608, Platelet degranulation |
Gene expression databases
Bgeei | ENSDARG00000060609, Expressed in gastrula and 12 other tissues |
Family and domain databases
CDDi | cd02897, A2M_2, 1 hit |
Gene3Di | 2.60.40.10, 2 hits 2.60.40.690, 1 hit |
InterProi | View protein in InterPro IPR036595, A-macroglobulin_rcpt-bd_sf IPR011625, A2M_N_BRD IPR041813, A2M_TED IPR011626, Alpha-macroglobulin_TED IPR013783, Ig-like_fold IPR001599, Macroglobln_a2 IPR019742, MacrogloblnA2_CS IPR002890, MG2 IPR041555, MG3 IPR008930, Terpenoid_cyclase/PrenylTrfase |
Pfami | View protein in Pfam PF00207, A2M, 1 hit PF07703, A2M_BRD, 1 hit PF01835, MG2, 1 hit PF17791, MG3, 1 hit PF07678, TED_complement, 1 hit |
SMARTi | View protein in SMART SM01360, A2M, 1 hit SM01359, A2M_N_2, 1 hit |
SUPFAMi | SSF48239, SSF48239, 1 hit |
PROSITEi | View protein in PROSITE PS00477, ALPHA_2_MACROGLOBULIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | I3IS91_DANRE | |
Accessioni | I3IS91Primary (citable) accession number: I3IS91 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 11, 2012 |
Last sequence update: | November 13, 2013 | |
Last modified: | December 2, 2020 | |
This is version 48 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |