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Entry version 16 (11 Dec 2019)
Sequence version 1 (11 Jul 2012)
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Protein
Submitted name:

RHS repeat-associated core domain protein

Gene

EC40522_0630

Organism
Escherichia coli 4.0522
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RHS repeat-associated core domain proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:EC40522_0630Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli 4.0522Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri869681 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000004262 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1493 – 1595Tox-REase-3InterPro annotationAdd BLAST103

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008727, PAAR_motif
IPR022385, Rhs_assc_core
IPR031325, RHS_repeat
IPR028905, Tox-REase-3_dom
IPR006530, YD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05488, PAAR_motif, 1 hit
PF05593, RHS_repeat, 6 hits
PF15647, Tox-REase-3, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

I2ULT2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEGPGGPQG ATAGGTLAMR MLSQQAMVAS QMKRAANDKA IAQMLAAKKS
60 70 80 90 100
GPPAARLGDE IQHKSFLGAL AGAVLGAIVT IAEGCLIMAA CATGPYALVL
110 120 130 140 150
VPALMYASYK ASDYVEEKQN QLESWINSFC DTDGAINTGS ENVNINGKPA
160 170 180 190 200
ARAAVTLPPP PPPGAIPEIP QGEPSWGDIA TDLLESAAEK AVPLAKAWGN
210 220 230 240 250
AVITLTESNA GFMDRVSAGA SLLFPAGPVL MEFATMVGGR SEIKKDVDFP
260 270 280 290 300
EAGEDTALCD KENKPPRIAQ GSSNVFINNQ PAARKGDKLE CSAAIVGGSP
310 320 330 340 350
DVFIGGEQVT YLDIQPEFPP WQRMILGGIT IASYLLPPAG LLGKLKNLAR
360 370 380 390 400
LGKLGNLLGK SGKQLGAKLG ALLGKTGKSL KSIANKVIRW VTDPVVPVTG
410 420 430 440 450
AYCDERTDFT LGQTLPLSFT RFHSSVLPLH GLTGVGWSDS WSEYAWVREQ
460 470 480 490 500
GNRVDIISQG ATLNFAFDGD SDTAVNPYHA QYILRRRDDY LELFDRDALS
510 520 530 540 550
SRFFYDAFPG MRLRHPVTDD TSDDRLAHSP DDRMYMLGGM SDTASNRITF
560 570 580 590 600
ERDSQYRITG VSHTDGIRLK LTYHASGYLK AIHRTDNGIQ TLATYEQDAR
610 620 630 640 650
GRLTEADARL DYHLFYEYDA ADRIIRWSDN DQTWSRFTYD AQGRCVNVTG
660 670 680 690 700
AEGYYNATLD YGDGCTTVTD GKGTHRYYYD PDGNILREEA PDGSTTTYEW
710 720 730 740 750
DEFHHLLARH SPAGRVEKFE YNAALGQLSR YTAADGAEWL YRYDERGLLS
760 770 780 790 800
NITDPAGQTW TQQCDERGLP VSLVSPQGEE TRLAYTAQGL LSGIFRQDER
810 820 830 840 850
RLGIEYDHHN RPETLTDVMG REHHTEYSGH DLPVKMRGPG GQSVRLQWQQ
860 870 880 890 900
HHKLSGLERA ETGAEGFRYD RHGNLLAYTD GNGVVWTMEY GPFDLPVART
910 920 930 940 950
DGEGHRWQYR YDKDTLQLTE VINPQGESYR YILDNCGRVT EERDWGGVVW
960 970 980 990 1000
RYRYDADGLC TARVNGLEET ILYSRDAAGR LAEVITPEGK TQYAYDKSGR
1010 1020 1030 1040 1050
LTGIFSPDGT SQRTGYDERG RVNVTTQGRR AIEYHYPDEH TVIRCILPPE
1060 1070 1080 1090 1100
DERDRHPDES LLKTTYRYNA AGELTEVILP GDETLTFSRD EAGREVLRHS
1110 1120 1130 1140 1150
NRGFACEQGW NAAGQPVSQR AGFFPEETTW GGLLPSLVRE YRYDSAGNVS
1160 1170 1180 1190 1200
AVTSREDYGR ETRREYRLDR NGQVTAVTAS GTGLGYGEGD ESYGYDSCGY
1210 1220 1230 1240 1250
LKAQSAGRHR ISEETDQYAG GHRLKQAGNT QYDYDAAGRM VSRTRHRDGY
1260 1270 1280 1290 1300
RPETERFRWD SRDQLTGYCS AQGEQWEYRH DASGRRTEKR CDRKKIRFTY
1310 1320 1330 1340 1350
LWDGDSIAEI REYRDDKLYS VRHLVFNGFE LISQQFSRVR QAHPSVAPQW
1360 1370 1380 1390 1400
VTRTNHAVSD LTGRPLMLFN SEGKTVWRPG QTSLWGLALS LPADTGYPDP
1410 1420 1430 1440 1450
RGEWDPEADP GLLYAGQWQD AESGLCYNRF RYYEPETGMY LVSDPLGLQG
1460 1470 1480 1490 1500
GEQTYRYVPN PLGYIDPLGL AKTSVPAEKI SLSDKARDLF RQGKVREALD
1510 1520 1530 1540 1550
VHYEDLVRRK LGGISQEIAG REYDVVTDKI IAQVKRTYSS IDNPKNFLSK
1560 1570 1580 1590
STRTQIKKTI ELAEEQGKEA QFWFKYGVSP KVREYIESKG GKVILGMGN
Length:1,599
Mass (Da):178,167
Last modified:July 11, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8EB254F268B21750
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEZU02000030 Genomic DNA Translation: EIH79158.1

NCBI Reference Sequences

More...
RefSeqi
WP_001289036.1, NZ_AEZU02000030.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
EIH79158; EIH79158; EC40522_0630

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEZU02000030 Genomic DNA Translation: EIH79158.1
RefSeqiWP_001289036.1, NZ_AEZU02000030.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiEIH79158; EIH79158; EC40522_0630

Family and domain databases

InterProiView protein in InterPro
IPR008727, PAAR_motif
IPR022385, Rhs_assc_core
IPR031325, RHS_repeat
IPR028905, Tox-REase-3_dom
IPR006530, YD
PfamiView protein in Pfam
PF05488, PAAR_motif, 1 hit
PF05593, RHS_repeat, 6 hits
PF15647, Tox-REase-3, 1 hit
TIGRFAMsiTIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 10 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI2ULT2_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I2ULT2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: December 11, 2019
This is version 16 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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