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UniProtKB - I1RAL2 (I1RAL2_GIBZE)
Protein
Protein-tyrosine-phosphatase
Gene
FG00543.1
Organism
Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum)
Status
Functioni
GO - Molecular functioni
- protein tyrosine/serine/threonine phosphatase activity Source: InterPro
- protein tyrosine phosphatase activity Source: UniProtKB-EC
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- cell division Source: UniProtKB-KW
- regulation of exit from mitosis Source: InterPro
Keywordsi
Molecular function | Hydrolase, Protein phosphataseARBA annotation |
Biological process | Cell cycle, Cell divisionARBA annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:FG00543.1Imported ORF Names:FGRAMPH1_01T01385Imported |
Organismi | Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum)Imported |
Taxonomic identifieri | 229533 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Hypocreomycetidae › Hypocreales › Nectriaceae › Fusarium › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | FungiDB:FGRAMPH1_01G01385 |
Subcellular locationi
Nucleus
- nucleus Source: UniProtKB-KW
Keywords - Cellular componenti
NucleusARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 244 – 401 | Tyrosine-protein phosphataseInterPro annotationAdd BLAST | 158 | |
Domaini | 321 – 387 | TYR_PHOSPHATASE_2InterPro annotationAdd BLAST | 67 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 431 – 499 | DisorderedSequence analysisAdd BLAST | 69 | |
Regioni | 514 – 552 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 568 – 633 | DisorderedSequence analysisAdd BLAST | 66 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 431 – 448 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 517 – 537 | Basic and acidic residuesSequence analysisAdd BLAST | 21 | |
Compositional biasi | 538 – 552 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 592 – 606 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 609 – 633 | Polar residuesSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.ARBA annotation
Phylogenomic databases
eggNOGi | KOG1720, Eukaryota |
HOGENOMi | CLU_017787_1_1_1 |
Family and domain databases
CDDi | cd14499, CDC14_C, 1 hit cd17657, CDC14_N, 1 hit |
Gene3Di | 3.90.190.10, 2 hits |
InterProi | View protein in InterPro IPR026070, CDC14 IPR044506, CDC14_C IPR029260, DSPn IPR000340, Dual-sp_phosphatase_cat-dom IPR029021, Prot-tyrosine_phosphatase-like IPR016130, Tyr_Pase_AS IPR003595, Tyr_Pase_cat IPR000387, Tyr_Pase_dom IPR020422, TYR_PHOSPHATASE_DUAL_dom |
PANTHERi | PTHR23339:SF27, PTHR23339:SF27, 1 hit |
Pfami | View protein in Pfam PF00782, DSPc, 1 hit PF14671, DSPn, 1 hit |
SMARTi | View protein in SMART SM00195, DSPc, 1 hit SM00404, PTPc_motif, 1 hit |
SUPFAMi | SSF52799, SSF52799, 2 hits |
PROSITEi | View protein in PROSITE PS00383, TYR_PHOSPHATASE_1, 1 hit PS50056, TYR_PHOSPHATASE_2, 1 hit PS50054, TYR_PHOSPHATASE_DUAL, 1 hit |
i Sequence
Sequence statusi: Complete.
I1RAL2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPSSRHPQL QPQPQSMAQI VEYIPDRLYL AAYNVAPTAD TPFPYPEEPA
60 70 80 90 100
PVSPRKRTTR LAAGATPLAK PSRPQPCYFT VDDTLLYNAF HHDFGPLHIG
110 120 130 140 150
HLYRFAIQFH DILGAKQNKE RPIVFYSAAD PKSRANAACM LACYMVLIQN
160 170 180 190 200
WPPHLALAPI AQVDPPLMPF RDAGYSQADY GISVQDVVYG VWKAKEEKCC
210 220 230 240 250
DLDNFDLDEY ERFERVEHGD FNWITPHFLA FASPQHAPVQ KVTEGSELFP
260 270 280 290 300
LLPRTIAAVD AHPKLPKPFK NVLKHFSEKN IGLVVRLNSQ LYSPSYFEAL
310 320 330 340 350
GIQHLDMIFD DGTCPSLTTV RKFIRLAHET ITVRKKGIAV HCKAGLGRTG
360 370 380 390 400
CLIGAYLIYR HGFTANEVIS FMRFMRPGMV VGPQQHWLHL NQGTFREWWV
410 420 430 440 450
EERIERRLRR EMAAANPIPS TPIRAMQKTT LRNGQASTPP NRSPSNRTPL
460 470 480 490 500
SEVDHDRNNI GVQEDYLPAP TPGQPRKTAR DRHHPYQRSI SGGVPPEAQY
510 520 530 540 550
PVDQEADLIA KYTQASGESD EELHLRMRRR KATSQSPARS EKTRSVSQTT
560 570 580 590 600
AIYTIDNDAS HDAENIGSVR SKYVERVPST PGVLAKVRGS KRQGESPLRA
610 620 630
KESGVRKTSG RVGSASHSTS VSAASTARKV SGA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HG970332 Genomic DNA Translation: CEF72493.1 |
RefSeqi | XP_011316222.1, XM_011317920.1 |
Genome annotation databases
EnsemblFungii | CEF72493; CEF72493; FGRRES_00543 |
GeneIDi | 23548031 |
KEGGi | fgr:FGSG_00543 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HG970332 Genomic DNA Translation: CEF72493.1 |
RefSeqi | XP_011316222.1, XM_011317920.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 229533.I1RAL2 |
Genome annotation databases
EnsemblFungii | CEF72493; CEF72493; FGRRES_00543 |
GeneIDi | 23548031 |
KEGGi | fgr:FGSG_00543 |
Organism-specific databases
VEuPathDBi | FungiDB:FGRAMPH1_01G01385 |
Phylogenomic databases
eggNOGi | KOG1720, Eukaryota |
HOGENOMi | CLU_017787_1_1_1 |
Family and domain databases
CDDi | cd14499, CDC14_C, 1 hit cd17657, CDC14_N, 1 hit |
Gene3Di | 3.90.190.10, 2 hits |
InterProi | View protein in InterPro IPR026070, CDC14 IPR044506, CDC14_C IPR029260, DSPn IPR000340, Dual-sp_phosphatase_cat-dom IPR029021, Prot-tyrosine_phosphatase-like IPR016130, Tyr_Pase_AS IPR003595, Tyr_Pase_cat IPR000387, Tyr_Pase_dom IPR020422, TYR_PHOSPHATASE_DUAL_dom |
PANTHERi | PTHR23339:SF27, PTHR23339:SF27, 1 hit |
Pfami | View protein in Pfam PF00782, DSPc, 1 hit PF14671, DSPn, 1 hit |
SMARTi | View protein in SMART SM00195, DSPc, 1 hit SM00404, PTPc_motif, 1 hit |
SUPFAMi | SSF52799, SSF52799, 2 hits |
PROSITEi | View protein in PROSITE PS00383, TYR_PHOSPHATASE_1, 1 hit PS50056, TYR_PHOSPHATASE_2, 1 hit PS50054, TYR_PHOSPHATASE_DUAL, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | I1RAL2_GIBZE | |
Accessioni | I1RAL2Primary (citable) accession number: I1RAL2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 13, 2012 |
Last sequence update: | June 13, 2012 | |
Last modified: | January 19, 2022 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |