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Entry version 40 (31 Jul 2019)
Sequence version 1 (13 Jun 2012)
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Protein

Histone-lysine N-methyltransferase

Gene
N/A
Organism
Oryza glaberrima (African rice)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone-lysine N-methyltransferasePROSITE-ProRule annotation (EC:2.1.1.43PROSITE-ProRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza glaberrima (African rice)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4538 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007306 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4538.ORGLA03G0142100.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini628 – 732CXCInterPro annotationAdd BLAST105
Domaini747 – 863SETInterPro annotationAdd BLAST117

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 28DisorderedSequence analysisAdd BLAST28
Regioni369 – 425DisorderedSequence analysisAdd BLAST57
Regioni485 – 507DisorderedSequence analysisAdd BLAST23
Regioni868 – 896DisorderedSequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 19PolarSequence analysisAdd BLAST19
Compositional biasi386 – 403PolarSequence analysisAdd BLAST18
Compositional biasi874 – 890PolyampholyteSequence analysisAdd BLAST17

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1079 Eukaryota
COG2940 LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
VARTRIC

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167 SANT, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026489 CXC_dom
IPR025778 Hist-Lys_N-MeTrfase_EZ
IPR041355 Pre-SET_CXC
IPR001005 SANT/Myb
IPR001214 SET_dom
IPR033467 Tesmin/TSO1-like_CXC

The PANTHER Classification System

More...
PANTHERi
PTHR45747:SF9 PTHR45747:SF9, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18264 preSET_CXC, 1 hit
PF00856 SET, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01114 CXC, 1 hit
SM00317 SET, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51633 CXC, 1 hit
PS51576 SAM_MT43_EZ, 1 hit
PS50280 SET, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

I1PAM5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSSSKASD SSSQRPKRPD QGPSGMDAAG LVALHGKLAQ LKRQVQSTRL
60 70 80 90 100
AAIKERVEAN RKALQVHTCA LFDVAAAAEV ASRGAEGGNA LSRGAAEGHR
110 120 130 140 150
RFVGWDSASG PGERELVHVQ EENLVAGTLV LSSSGGSGAS HRTVVQLVKL
160 170 180 190 200
PVVDKIPPYT TWIFLDKNQR MADDQSVGRR RIYYDPIVNE ALICSESDDD
210 220 230 240 250
VPEPEEEKHV FTEGEDQLIW KATQDHGLSR EVLHVLCQFV DATPSEIEER
260 270 280 290 300
SEVLFEKYEK QSQSSYKTDL QLFLDKTIDV ALDSFDNLFC RRCLVFDCRL
310 320 330 340 350
HGCSQNLVFP SEKQPYGHEL DENKRPCGDQ CYLRRREVYQ DTCNDDRNAC
360 370 380 390 400
TTYNMDSRSS SLKVSATILS ESEDSNRDED NIKSTSIVET SRSKITNSEY
410 420 430 440 450
ADKSVTPPPG DASETENVSP DMPLRTLGRR KISKHASKSN DHSPDKRQKI
460 470 480 490 500
YSSPFPFAMS VLNKQSVPEI GETCPDSIES AVDQLPSLDD PNKKISTKDM
510 520 530 540 550
CAGSTTNTTE NTLRDNNNNL FISNKEHSIS HWSALERDLY LKGIEIFGKN
560 570 580 590 600
SCLIARNLLS GLKTCMEVAS YMYNNGAAMA KRPLSGKSIL GDFAEAEQGY
610 620 630 640 650
MEQDLVARTR ICRRKGRARK LKYTWKSAGH PTVRKRIGDG KQWYTQYNPC
660 670 680 690 700
GCQQMCGKDC ACVENGTCCE KYCGCSKSCK NRFRGCHCAK SQCRSRQCPC
710 720 730 740 750
FAASRECDPD VCRNCWVSCG DGSLGEPLAR GDGYQCGNMK LLLKQQQRIL
760 770 780 790 800
LGKSDVAGWG AFIKNPVNRN DYLGEYTGEL ISHREADKRG KIYDRANSSF
810 820 830 840 850
LFDLNEQQYV LDAYRKGDKL KFANHSSNPN CYAKVMLVAG DHRVGIYAKD
860 870 880 890
RIEASEELFY DYRYGPDQAP AWARRPEGSK KDEASVSHHR AHKVAR
Length:896
Mass (Da):99,999
Last modified:June 13, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i32CD34C19FE6689B
GO

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
ORGLA03G0142100.1; ORGLA03G0142100.1; ORGLA03G0142100

Gramene; a comparative resource for plants

More...
Gramenei
ORGLA03G0142100.1; ORGLA03G0142100.1; ORGLA03G0142100

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi4538.ORGLA03G0142100.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiORGLA03G0142100.1; ORGLA03G0142100.1; ORGLA03G0142100
GrameneiORGLA03G0142100.1; ORGLA03G0142100.1; ORGLA03G0142100

Phylogenomic databases

eggNOGiKOG1079 Eukaryota
COG2940 LUCA
OMAiVARTRIC

Family and domain databases

CDDicd00167 SANT, 1 hit
InterProiView protein in InterPro
IPR026489 CXC_dom
IPR025778 Hist-Lys_N-MeTrfase_EZ
IPR041355 Pre-SET_CXC
IPR001005 SANT/Myb
IPR001214 SET_dom
IPR033467 Tesmin/TSO1-like_CXC
PANTHERiPTHR45747:SF9 PTHR45747:SF9, 1 hit
PfamiView protein in Pfam
PF18264 preSET_CXC, 1 hit
PF00856 SET, 1 hit
SMARTiView protein in SMART
SM01114 CXC, 1 hit
SM00317 SET, 1 hit
PROSITEiView protein in PROSITE
PS51633 CXC, 1 hit
PS51576 SAM_MT43_EZ, 1 hit
PS50280 SET, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI1PAM5_ORYGL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I1PAM5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: July 31, 2019
This is version 40 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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