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Protein

Importin subunit alpha

Gene

LOC100846088

Organism
Brachypodium distachyon (Purple false brome) (Trachynia distachya)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
Name:LOC100846088Imported
Synonyms:100846088Imported
ORF Names:BRADI_2g08960v3Imported
OrganismiBrachypodium distachyon (Purple false brome) (Trachynia distachya)Imported
Taxonomic identifieri15368 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeBrachypodieaeBrachypodium
Proteomesi
  • UP000008810 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Subunit structurei

Forms a complex with importin subunit beta-1.UniRule annotation

Protein-protein interaction databases

STRINGi15368.BRADI2G08960.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 58IBBInterPro annotationAdd BLAST58
Repeati112 – 155ARMPROSITE-ProRule annotationAdd BLAST44
Repeati155 – 197ARMPROSITE-ProRule annotationAdd BLAST43
Repeati239 – 281ARMPROSITE-ProRule annotationAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili36 – 56Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
InParanoidiI1HDY9
OMAiPYAITIE
OrthoDBiEOG09360724

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 3 hits
PS51214 IBB, 1 hit

Sequencei

Sequence statusi: Complete.

I1HDY9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLRPNERVE ARKSSYKSTV DADDGRRRRE GDMVEIRKSR REESLLKKRR
60 70 80 90 100
EGLQAQAPVP AAGVEKKLES LPAMVAGVYS DDINLQLEAT TQFRKLLSIE
110 120 130 140 150
RSPPIEEVIK SGVVPRFVQC LGRDDFPQLQ FEAAWALTNI ASGTSENTKV
160 170 180 190 200
VIDHGAVPIF VKLLGSGSDD VREQAVWALG NVAGDSPRCR DLVLESGALM
210 220 230 240 250
PLLAQLNEHA KLSMLRNATW TLSNFCRGKP QPAFDQTKPA LPALARLIHS
260 270 280 290 300
NDEEVLTDAC WALSYLSDGT NDKIQSVIDA GVCPRLVELL LHPSPSVLIP
310 320 330 340 350
ALRTVGNIVT GDDSQTQCII DHQALACLLS LLTQNHKKSI KKEACWTVSN
360 370 380 390 400
ITAGNKDQIQ AVINAGIIGP LVHLLQTAEF DIKKEAAWAI SNATSGGSHD
410 420 430 440 450
QIKYLVSEGC IKPLCDLLIC PDSRIVTVCL EGLENILKVG ETDKNLGGDG
460 470 480 490 500
NVYALMIDEA EGLEKIENLQ SHDNNEIYEK AVKILEAYWM DEEDDAMGGA
510 520
MEASQGVSFD FGQGGNPDLN LG
Length:522
Mass (Da):56,899
Last modified:June 13, 2012 - v1
Checksum:iD2B35ED70B2A9ED3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000881 Genomic DNA Translation: KQK03624.1
RefSeqiXP_003566399.1, XM_003566351.3

Genome annotation databases

EnsemblPlantsiBRADI2G08960.1; BRADI2G08960.1; BRADI2G08960
KQK03624; KQK03624; BRADI_2g08960v3
GeneIDi100846088
KEGGibdi:100846088

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000881 Genomic DNA Translation: KQK03624.1
RefSeqiXP_003566399.1, XM_003566351.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi15368.BRADI2G08960.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiBRADI2G08960.1; BRADI2G08960.1; BRADI2G08960
KQK03624; KQK03624; BRADI_2g08960v3
GeneIDi100846088
KEGGibdi:100846088

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
InParanoidiI1HDY9
OMAiPYAITIE
OrthoDBiEOG09360724

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 3 hits
PS51214 IBB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI1HDY9_BRADI
AccessioniPrimary (citable) accession number: I1HDY9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: October 10, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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