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Protein

DNA polymerase

Gene

RO3G_04261

Organism
Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation, DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase
Biological processDNA replicationUniRule annotation
Ligand4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
ORF Names:RO3G_04261Imported
OrganismiRhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)Imported
Taxonomic identifieri246409 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisMucoromycotaMucoromycotinaMucoromycetesMucoralesMucorineaeRhizopodaceaeRhizopus
Proteomesi
  • UP000009138 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 69DNA_pol_alpha_NInterPro annotationAdd BLAST58
Domaini305 – 638DNA_pol_B_exo1InterPro annotationAdd BLAST334
Domaini698 – 1166DNA_pol_BInterPro annotationAdd BLAST469
Domaini1204 – 1315zf-DNA_PolInterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Keywords - Domaini

Zinc-fingerUniRule annotation

Phylogenomic databases

InParanoidiI1BTM6
OrthoDBiEOG092C038B

Family and domain databases

Gene3Di1.10.3200.20, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 1 hit
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR017964 DNA-dir_DNA_pol_B_CS
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR024647 DNA_pol_a_cat_su_N
IPR023211 DNA_pol_palm_dom_sf
IPR038256 Pol_alpha_znc_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR015088 Znf_DNA-dir_DNA_pol_B_alpha
PfamiView protein in Pfam
PF12254 DNA_pol_alpha_N, 1 hit
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08996 zf-DNA_Pol, 1 hit
PRINTSiPR00106 DNAPOLB
SMARTiView protein in SMART
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS00116 DNA_POLYMERASE_B, 1 hit

Sequencei

Sequence statusi: Complete.

I1BTM6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSSRAERD NKLKKLRDAM RSKRKSKTIQ DDDDLYEEIE ENDYLAIQDD
60 70 80 90 100
EAFVEDDDKG GYIDNGEEEE YNYSDEYETE VEKISSGKRK RKIKQKQPST
110 120 130 140 150
PVKPNQQINK FFSSSMIKKH TAEKPIKHKP IDKEESDSFL NDLLSEFNTP
160 170 180 190 200
TKQERKAPVN VPVREKPAVN HLSRLSQMRT PIQRASLLAQ QQQPEPPIAQ
210 220 230 240 250
EISEPSVPTS SELELESIDF DDIMNDIKVE SINQIEMSNN KPTFSTLEPA
260 270 280 290 300
TIAPGLQGWE DADASMIDTF AQDTVKEESQ SVNVFEEDGH LRMWWYDAYE
310 320 330 340 350
RKEKGYVYLF ASGNSTDKEV EITDVYEEVS ELFSKHRITK YASKKVSRKY
360 370 380 390 400
AFELHDVPAE SDYLKVLYDY EQPSLTGTET GKTFSRVFGA NTGPLEHFLV
410 420 430 440 450
KRDIMGPCWL DISGAQMSKT SETWCKVEVT VEDPKTVNPL VDETGNRPIH
460 470 480 490 500
VPPLIVMSLC LRTIMNSKKN VNEIVAASAL VCNQVQIDDT KSLEEQTKMR
510 520 530 540 550
FTVVRQLESQ PYPAGFMEMV GKEKKKSGGF SIQAERTEAS LLNFLIARIH
560 570 580 590 600
LCDPDVIVGH NFAGFDLDVL LHRMKALNIQ HWHRLGRLKR KNWPKLQAGA
610 620 630 640 650
GGVGESTFQE RMIMSGRLVC DTYLASKDLI RSKSYRLTDL AQSQLKIARE
660 670 680 690 700
DIEFGKSEEY FENSNNLFHF LKHCSFDAYL STSLMFKLQV LPLTHQLTAL
710 720 730 740 750
AGNLWARTMT GARAERNEFL LLHEFHKAKY ICPDKTFGNK ESVSVGQAVV
760 770 780 790 800
QAAEQDDDED ALKEVSNVKK SGRRKPAYAG GLVLEPKKGF YDKYVLLLDF
810 820 830 840 850
NSLYPSIIQE YNVCFTTVDR SAFQQGNEKN EEEKVPDVPG DSVPEGILPK
860 870 880 890 900
LLKTLVDRRR QVKNAMKGEK SEAKYNQLNI RQQALKLTAN SMYGCLGFTY
910 920 930 940 950
SRFYAKPLAM LITFKGREIL QSTVNLAGNL DMNVIYGDTD SIMVYTNQND
960 970 980 990 1000
LNEVKKMGNL LRKKVNDHYK LLEIGIDGYF KHMLLLKKKK YAALLVEEKD
1010 1020 1030 1040 1050
NGELVESVET KGLDLVRRDW CDLSHDVSSH VLDLILSDKE RDEVVNEIHT
1060 1070 1080 1090 1100
YLEVTVERIR QGEIPLEKYV INKQLTKRPQ DYADAKSQPH VQVALRMIAA
1110 1120 1130 1140 1150
GQGVKSGDTV PYVICKVDEE TSGDKKGSAL RAYHPDDVVK KNMQLDIEWY
1160 1170 1180 1190 1200
LQQQVHPPLT RLCSPIEGTD PARLAGCLGL EASRYRHFSG GMGEDEQELV
1210 1220 1230 1240 1250
TLDSQISDAE RFKSSEALLL TCNNCDKEFK YEGILRQTED TIECGLKCVH
1260 1270 1280 1290 1300
CYQVIHYASL KAQLILNIRN YIDRYYQGWL LCDDPTCGNR TRMISVFGRR
1310
CLADECRGTM KREVNMKLS
Length:1,319
Mass (Da):150,385
Last modified:June 13, 2012 - v1
Checksum:i4E45708AAE43DE74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476734 Genomic DNA Translation: EIE79556.1

Genome annotation databases

EnsemblFungiiEIE79556; EIE79556; RO3G_04261

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476734 Genomic DNA Translation: EIE79556.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEIE79556; EIE79556; RO3G_04261

Phylogenomic databases

InParanoidiI1BTM6
OrthoDBiEOG092C038B

Family and domain databases

Gene3Di1.10.3200.20, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 1 hit
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR017964 DNA-dir_DNA_pol_B_CS
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR024647 DNA_pol_a_cat_su_N
IPR023211 DNA_pol_palm_dom_sf
IPR038256 Pol_alpha_znc_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR015088 Znf_DNA-dir_DNA_pol_B_alpha
PfamiView protein in Pfam
PF12254 DNA_pol_alpha_N, 1 hit
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08996 zf-DNA_Pol, 1 hit
PRINTSiPR00106 DNAPOLB
SMARTiView protein in SMART
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS00116 DNA_POLYMERASE_B, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI1BTM6_RHIO9
AccessioniPrimary (citable) accession number: I1BTM6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: November 7, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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