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Entry version 66 (26 Feb 2020)
Sequence version 1 (16 May 2012)
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Protein
Submitted name:

Membrane protein

Gene

sciP

Organism
Salmonella typhimurium
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Membrane proteinImported
Submitted name:
SciP proteinImported
Submitted name:
Type VI secretion system protein TssLImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sciPImported
Synonyms:oprFImported, tssLImported
ORF Names:AAP89_22480Imported, ABO94_08600Imported, AF480_23425Imported, AF488_23755Imported, AF489_09080Imported, AU613_06240Imported, AXR84_14180Imported, AXU58_22350Imported, C2253_21825Imported, CE87_15905Imported, CET98_23850Imported, CQG18_14205Imported, CVR97_22360Imported, D4369_23400Imported, D4401_23315Imported, D6360_19250Imported, D7F20_20610Imported, D7H43_21955Imported, DD95_17720Imported, DJ388_07030Imported, DKJ11_16945Imported, DKU57_21115Imported, DNV30_20910Imported, DO698_17950Imported, DOJ90_11475Imported, DQ848_20080Imported, DRM14_20350Imported, DSF69_22115Imported, DSR36_21350Imported, DUW48_15600Imported, EBO41_22295Imported, EBP31_21385Imported, EGU67_22030Imported, EHB24_20570Imported, EHC98_22295Imported, EIW53_20600Imported, GW08_07970Imported, JO10_08670Imported, LZ63_13250Imported, NG18_21390Imported, NU83_12060Imported, QA89_16400Imported, QB40_20730Imported, QD15_18180Imported, RJ78_23580Imported, SAMEA4398682_03744Imported, Y934_24065Imported, YG50_17190Imported, YI33_22000Imported, YR17_13705Imported, ZB89_23080Imported, ZC54_22705Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSalmonella typhimuriumImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri90371 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000228538 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000267021 Componenti: Unassembled WGS sequence
  • UP000277261 Componenti: Unassembled WGS sequence
  • UP000054461 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei243 – 263HelicalSequence analysisAdd BLAST21

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
90371.CY43_01410

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini316 – 434OmpA-likeInterPro annotationAdd BLAST119

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105NIK Bacteria
COG1360 LUCA
COG3455 LUCA

KEGG Orthology (KO)

More...
KOi
K11892

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07185 OmpA_C-like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.590, 1 hit
3.30.1330.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006665 OmpA-like
IPR036737 OmpA-like_sf
IPR017733 OmpA/MotB_dom
IPR017732 T4/T6SS_DotU
IPR038522 T4/T6SS_DotU_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09850 DotU, 1 hit
PF00691 OmpA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103088 SSF103088, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03349 IV_VI_DotU, 1 hit
TIGR03350 type_VI_ompA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51123 OMPA_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9L4F7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDSTLTPPA ADMMSFLSTT PEHKDSEYET PVHTSQRTEL NVIVEDGPDS
60 70 80 90 100
KLRLAEISAA ANPLLAAARP LLCALAAMPA KLDAALVEPY RNLLVREMHL
110 120 130 140 150
YQTLCDQANL RREHVLAVRY CLCTALDEAA NNTTWGRRGV WAGKSLLVTF
160 170 180 190 200
HGESEGGIKL FQIIGRLAAS FQEHGNVLEV IYHLLGLGFE GRYSVQPDGR
210 220 230 240 250
KQLDNIRQQL LTQLSQRRDP VMPALSPDFQ GAISGRLRRM RRVPVWLSAG
260 270 280 290 300
IALLAMLTLF GLYSHRMDVQ TVTVQQHIDA IGIKLPPPPV PVHKLRLKIL
310 320 330 340 350
LANEIARGLL TVDEDDQHSR VVFRGDAMFV PGQKTVSDAI RPVINKAARE
360 370 380 390 400
IARVGGAVTV TGHTDSQPIH SAEFPSNLVL SEKRAAEVAA LLTSGGVPAG
410 420 430
RVHIVGKGDT VPVADNGSKA GRAKNRRVEI LVVE
Length:434
Mass (Da):47,356
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D787A09B8AB092D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ320483 Genomic DNA Translation: CAC48213.1
AAAAHH010000018 Genomic DNA Translation: EAA0479004.1
AAAAJL010000029 Genomic DNA Translation: EAA0854336.1
AAAALU010000007 Genomic DNA Translation: EAA1158708.1
AAAAXX010000068 Genomic DNA Translation: EAA2676008.1
AAAAYX010000031 Genomic DNA Translation: EAA2722976.1
AAABHL010000012 Genomic DNA Translation: EAA3843075.1
AAABKD010000033 Genomic DNA Translation: EAA4098254.1
AAABXM010000039 Genomic DNA Translation: EAA5737614.1
AAABXQ010000022 Genomic DNA Translation: EAA5770537.1
AAACCL010000027 Genomic DNA Translation: EAA6355814.1
AAACDS010000024 Genomic DNA Translation: EAA6487123.1
AAACJA010000036 Genomic DNA Translation: EAA7175185.1
AAACKB010000021 Genomic DNA Translation: EAA7217013.1
AAACKA010000029 Genomic DNA Translation: EAA7297683.1
AAACKE010000024 Genomic DNA Translation: EAA7329351.1
AAACLH010000028 Genomic DNA Translation: EAA7449969.1
AAACMS010000003 Genomic DNA Translation: EAA7664980.1
AAACOB010000015 Genomic DNA Translation: EAA7812666.1
AAACPZ010000029 Genomic DNA Translation: EAA8002970.1
AAACSV010000003 Genomic DNA Translation: EAA8346131.1
AAACTN010000006 Genomic DNA Translation: EAA8430798.1
AAACUH010000010 Genomic DNA Translation: EAA8507199.1
AAACTG010000032 Genomic DNA Translation: EAA8550370.1
AAADBH010000009 Genomic DNA Translation: EAA9375728.1
AAAFCL010000033 Genomic DNA Translation: EAB5652104.1
AAAFFB010000033 Genomic DNA Translation: EAB5975325.1
AAAFEY010000032 Genomic DNA Translation: EAB6024194.1
AAAFLB010000036 Genomic DNA Translation: EAB6679063.1
AAAFLR010000013 Genomic DNA Translation: EAB6833576.1
AAAFOM010000038 Genomic DNA Translation: EAB7115490.1
AAAFOJ010000022 Genomic DNA Translation: EAB7194968.1
AAAFRV010000032 Genomic DNA Translation: EAB7514548.1
AAAFYT010000039 Genomic DNA Translation: EAB8455636.1
AAAFZR010000028 Genomic DNA Translation: EAB8515921.1
AAAFZS010000010 Genomic DNA Translation: EAB8559924.1
AAAGCC010000037 Genomic DNA Translation: EAB8744090.1
AAAGBU010000016 Genomic DNA Translation: EAB8822746.1
AAAGLW010000031 Genomic DNA Translation: EAB9961473.1
AAAGPP010000011 Genomic DNA Translation: EAC0509818.1
AAAGQC010000036 Genomic DNA Translation: EAC0530126.1
AAAGRV010000032 Genomic DNA Translation: EAC0725154.1
AAAGUK010000040 Genomic DNA Translation: EAC1020201.1
AAAGVF010000022 Genomic DNA Translation: EAC1147279.1
AAAGVW010000030 Genomic DNA Translation: EAC1299686.1
AAAGZF010000021 Genomic DNA Translation: EAC1539485.1
AAAHBU010000019 Genomic DNA Translation: EAC1708580.1
AAAHGK010000004 Genomic DNA Translation: EAC2167026.1
JYVU01000046 Genomic DNA Translation: KTZ09478.1
RSUA01000008 Genomic DNA Translation: MIT48484.1
RVDJ01000025 Genomic DNA Translation: MLP87628.1
PHGX01000082 Genomic DNA Translation: PJH59809.1
CABIII010000001 Genomic DNA Translation: VUZ11192.1

NCBI Reference Sequences

More...
RefSeqi
WP_000132483.1, NZ_WACM01000004.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
KKE09190; KKE09190; TJ44_05245
KTZ09478; KTZ09478; DD95_17720

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
seni:CY43_01410

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|90371.1185.peg.295

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ320483 Genomic DNA Translation: CAC48213.1
AAAAHH010000018 Genomic DNA Translation: EAA0479004.1
AAAAJL010000029 Genomic DNA Translation: EAA0854336.1
AAAALU010000007 Genomic DNA Translation: EAA1158708.1
AAAAXX010000068 Genomic DNA Translation: EAA2676008.1
AAAAYX010000031 Genomic DNA Translation: EAA2722976.1
AAABHL010000012 Genomic DNA Translation: EAA3843075.1
AAABKD010000033 Genomic DNA Translation: EAA4098254.1
AAABXM010000039 Genomic DNA Translation: EAA5737614.1
AAABXQ010000022 Genomic DNA Translation: EAA5770537.1
AAACCL010000027 Genomic DNA Translation: EAA6355814.1
AAACDS010000024 Genomic DNA Translation: EAA6487123.1
AAACJA010000036 Genomic DNA Translation: EAA7175185.1
AAACKB010000021 Genomic DNA Translation: EAA7217013.1
AAACKA010000029 Genomic DNA Translation: EAA7297683.1
AAACKE010000024 Genomic DNA Translation: EAA7329351.1
AAACLH010000028 Genomic DNA Translation: EAA7449969.1
AAACMS010000003 Genomic DNA Translation: EAA7664980.1
AAACOB010000015 Genomic DNA Translation: EAA7812666.1
AAACPZ010000029 Genomic DNA Translation: EAA8002970.1
AAACSV010000003 Genomic DNA Translation: EAA8346131.1
AAACTN010000006 Genomic DNA Translation: EAA8430798.1
AAACUH010000010 Genomic DNA Translation: EAA8507199.1
AAACTG010000032 Genomic DNA Translation: EAA8550370.1
AAADBH010000009 Genomic DNA Translation: EAA9375728.1
AAAFCL010000033 Genomic DNA Translation: EAB5652104.1
AAAFFB010000033 Genomic DNA Translation: EAB5975325.1
AAAFEY010000032 Genomic DNA Translation: EAB6024194.1
AAAFLB010000036 Genomic DNA Translation: EAB6679063.1
AAAFLR010000013 Genomic DNA Translation: EAB6833576.1
AAAFOM010000038 Genomic DNA Translation: EAB7115490.1
AAAFOJ010000022 Genomic DNA Translation: EAB7194968.1
AAAFRV010000032 Genomic DNA Translation: EAB7514548.1
AAAFYT010000039 Genomic DNA Translation: EAB8455636.1
AAAFZR010000028 Genomic DNA Translation: EAB8515921.1
AAAFZS010000010 Genomic DNA Translation: EAB8559924.1
AAAGCC010000037 Genomic DNA Translation: EAB8744090.1
AAAGBU010000016 Genomic DNA Translation: EAB8822746.1
AAAGLW010000031 Genomic DNA Translation: EAB9961473.1
AAAGPP010000011 Genomic DNA Translation: EAC0509818.1
AAAGQC010000036 Genomic DNA Translation: EAC0530126.1
AAAGRV010000032 Genomic DNA Translation: EAC0725154.1
AAAGUK010000040 Genomic DNA Translation: EAC1020201.1
AAAGVF010000022 Genomic DNA Translation: EAC1147279.1
AAAGVW010000030 Genomic DNA Translation: EAC1299686.1
AAAGZF010000021 Genomic DNA Translation: EAC1539485.1
AAAHBU010000019 Genomic DNA Translation: EAC1708580.1
AAAHGK010000004 Genomic DNA Translation: EAC2167026.1
JYVU01000046 Genomic DNA Translation: KTZ09478.1
RSUA01000008 Genomic DNA Translation: MIT48484.1
RVDJ01000025 Genomic DNA Translation: MLP87628.1
PHGX01000082 Genomic DNA Translation: PJH59809.1
CABIII010000001 Genomic DNA Translation: VUZ11192.1
RefSeqiWP_000132483.1, NZ_WACM01000004.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi90371.CY43_01410

Genome annotation databases

EnsemblBacteriaiKKE09190; KKE09190; TJ44_05245
KTZ09478; KTZ09478; DD95_17720
KEGGiseni:CY43_01410
PATRICifig|90371.1185.peg.295

Phylogenomic databases

eggNOGiENOG4105NIK Bacteria
COG1360 LUCA
COG3455 LUCA
KOiK11892

Family and domain databases

CDDicd07185 OmpA_C-like, 1 hit
Gene3Di1.25.40.590, 1 hit
3.30.1330.60, 1 hit
InterProiView protein in InterPro
IPR006665 OmpA-like
IPR036737 OmpA-like_sf
IPR017733 OmpA/MotB_dom
IPR017732 T4/T6SS_DotU
IPR038522 T4/T6SS_DotU_sf
PfamiView protein in Pfam
PF09850 DotU, 1 hit
PF00691 OmpA, 1 hit
SUPFAMiSSF103088 SSF103088, 1 hit
TIGRFAMsiTIGR03349 IV_VI_DotU, 1 hit
TIGR03350 type_VI_ompA, 1 hit
PROSITEiView protein in PROSITE
PS51123 OMPA_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9L4F7_SALTM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9L4F7
Secondary accession number(s): A0A0F7J5P1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: February 26, 2020
This is version 66 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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