UniProtKB - H9GVM3 (H9GVM3_ANOCA)
Protein
Submitted name:
Teashirt zinc finger homeobox 2
Gene
TSHZ2
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- chromatin binding Source: GO_Central
- DNA binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Teashirt zinc finger homeobox 2Imported |
Gene namesi | Name:TSHZ2Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSACAG00000012691, Expressed in forelimb bud and 10 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 264 – 293 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 914 – 941 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 981 – 1009 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 72 | DisorderedSequence analysisAdd BLAST | 72 | |
Regioni | 227 – 254 | DisorderedSequence analysisAdd BLAST | 28 | |
Regioni | 420 – 474 | DisorderedSequence analysisAdd BLAST | 55 | |
Regioni | 607 – 676 | DisorderedSequence analysisAdd BLAST | 70 | |
Regioni | 748 – 778 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 1001 – 1021 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 24 | AcidicSequence analysisAdd BLAST | 24 | |
Compositional biasi | 51 – 72 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 420 – 446 | PolarSequence analysisAdd BLAST | 27 | |
Compositional biasi | 447 – 474 | PolyampholyteSequence analysisAdd BLAST | 28 | |
Compositional biasi | 634 – 658 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 659 – 676 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 762 – 778 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 1002 – 1021 | PolyampholyteSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the teashirt C2H2-type zinc-finger protein family.ARBA annotation
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | ENOG502QV71, Eukaryota |
GeneTreei | ENSGT00950000183051 |
HOGENOMi | CLU_010469_0_0_1 |
InParanoidi | H9GVM3 |
OMAi | MKYQYLR |
TreeFami | TF328447 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR001356, Homeobox_dom IPR027008, Teashirt_fam IPR027010, Tshz2 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR12487, PTHR12487, 1 hit PTHR12487:SF3, PTHR12487:SF3, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
H9GVM3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GYGQEDDSKD EEDIKEEEEE EDNESSSTAH PQGSNEPGTD EEHDIGPDPK
60 70 80 90 100
GSFSYQNSPV SHISNQDAEN ESLLSDASDQ VADIKTLCSR EAQDSKANVH
110 120 130 140 150
PKHPTEAHSC MDKMTAVYAN ILSDSYWTGL GLGLKLSNSE KKGCDNRNGA
160 170 180 190 200
SKSDFDWHQD ALTKSLQQSL PARPVCKPNL FSSVQLYRQS SKMCGTVFTG
210 220 230 240 250
ASRFRCRQCS AAYDTLVELT VHMNESGHYQ DDNHKKDKHR PTSYSKPRKR
260 270 280 290 300
AFQDMDKEDA QKVLKCMFCG DSFDSLQDLS VHMIKTKHYQ KVPLKEPVPT
310 320 330 340 350
ISSKIVTPAK KRVFDINRPC SPDSTTGSFA DTFSSQKNAN LQLSSNNRYG
360 370 380 390 400
YQNGASYTWQ FEACKSQILK CMECGSSHDT LQQLTTHMMV TGHFLKVTSS
410 420 430 440 450
ASKKGKQLVL DPLAVEKMQS LSETPASDSQ PSKPSSNVST DSTSPAVELK
460 470 480 490 500
KEGKQNKSED VNKEEKMVKS EDYEDMLQKP LDPTIKYQYL REEDLEDASK
510 520 530 540 550
GGGDILKSLE NTVTSAINKA QNGAPSWSAY PSIHAAYQLS ESTKPSLPVG
560 570 580 590 600
SQVLQVRPTV TNKLRPIAPK WKVMPLVPVS ANMSQCTQVK KEGDTKKEVQ
610 620 630 640 650
KDYMKEGNKT DPASACQNEE ESPPQAEVCV EPKKSEPSPL KEESKAKEDE
660 670 680 690 700
EKEQTKSKES VTSLLSNGCA SSNHSSELPC LNPLSALQSV LNNHLGKANE
710 720 730 740 750
PLRPQQNSSP SAGSVSIFHK SNLNMIEKPV LSPAPTPTKP ARRYVFENND
760 770 780 790 800
QPIDLTKSKS KKGESVQAQS CTSPSQKHAL SDIADMVKVL PKATTPKPAA
810 820 830 840 850
SSRIPSMKLE MDVRRFEDVS TEVSTLHKRK GRQSNWNPQH LLILQAQFAS
860 870 880 890 900
SLFQTSEGKY LLSDLGPQER MQISKFTGLS MTTISHWLAN VKYQLRKTGG
910 920 930 940 950
TKFLKNMDKG HPIFYCSDCA SQFRTPSTYI SHLESHLGFQ MKDMNKLAVE
960 970 980 990 1000
QQTKVEQEIS RISVQRSPET IAVEEDTDSK FKCKLCSRTF VSKHAVKLHL
1010 1020
SKTHSKSPEH HSQFVAEVDE E
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02020590 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSACAT00000012695; ENSACAP00000021444; ENSACAG00000012691 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02020590 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000021444 |
Genome annotation databases
Ensembli | ENSACAT00000012695; ENSACAP00000021444; ENSACAG00000012691 |
Phylogenomic databases
eggNOGi | ENOG502QV71, Eukaryota |
GeneTreei | ENSGT00950000183051 |
HOGENOMi | CLU_010469_0_0_1 |
InParanoidi | H9GVM3 |
OMAi | MKYQYLR |
TreeFami | TF328447 |
Gene expression databases
Bgeei | ENSACAG00000012691, Expressed in forelimb bud and 10 other tissues |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR001356, Homeobox_dom IPR027008, Teashirt_fam IPR027010, Tshz2 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR12487, PTHR12487, 1 hit PTHR12487:SF3, PTHR12487:SF3, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GVM3_ANOCA | |
Accessioni | H9GVM3Primary (citable) accession number: H9GVM3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | May 16, 2012 | |
Last modified: | October 7, 2020 | |
This is version 44 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |