UniProtKB - H9GJP8 (H9GJP8_ANOCA)
Protein
ICAT domain-containing protein
Gene
CTNNBIP1
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- armadillo repeat domain binding Source: Ensembl
- beta-catenin binding Source: GO_Central
GO - Biological processi
- anterior/posterior pattern specification Source: Ensembl
- branching involved in ureteric bud morphogenesis Source: Ensembl
- negative regulation of DNA binding Source: Ensembl
- negative regulation of DNA-binding transcription factor activity Source: Ensembl
- negative regulation of mesenchymal cell proliferation Source: Ensembl
- negative regulation of protein binding Source: Ensembl
- negative regulation of protein-containing complex assembly Source: Ensembl
- negative regulation of smooth muscle cell proliferation Source: Ensembl
- negative regulation of transcription initiation from RNA polymerase II promoter Source: Ensembl
- negative regulation of Wnt signaling pathway Source: GO_Central
- positive regulation of monocyte differentiation Source: Ensembl
- positive regulation of osteoblast differentiation Source: Ensembl
- regulation of vascular permeability involved in acute inflammatory response Source: Ensembl
- Wnt signaling pathway Source: Ensembl
Names & Taxonomyi
Protein namesi | Recommended name: ICAT domain-containing proteinInterPro annotation |
Gene namesi | Name:CTNNBIP1Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Nucleus
- nucleus Source: GO_Central
Other locations
- beta-catenin destruction complex Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000013203, Expressed in brain and 15 other tissues |
Interactioni
GO - Molecular functioni
- armadillo repeat domain binding Source: Ensembl
- beta-catenin binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000012950 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 80 | ICATInterPro annotationAdd BLAST | 78 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 58 – 83 | DisorderedSequence analysisAdd BLAST | 26 |
Sequence similaritiesi
Belongs to the CTNNBIP1 family.ARBA annotation
Phylogenomic databases
eggNOGi | ENOG502S3XR, Eukaryota |
GeneTreei | ENSGT00940000161133 |
HOGENOMi | CLU_145119_1_0_1 |
InParanoidi | H9GJP8 |
OMAi | SHEEMYI |
Family and domain databases
Gene3Di | 1.10.10.490, 1 hit |
InterProi | View protein in InterPro IPR042999, CTNNBIP1 IPR009428, ICAT_dom IPR036911, ICAT_sf |
PANTHERi | PTHR47142, PTHR47142, 1 hit |
Pfami | View protein in Pfam PF06384, ICAT, 1 hit |
SUPFAMi | SSF81730, SSF81730, 1 hit |
i Sequence
Sequence statusi: Complete.
H9GJP8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
KGMNREGVPG KSPEEMYIQQ KVRVLLMLRK MGSNLTTSEE EFLRTYAGVV
60 70 80
NSQLSQLPQH SIDQGAEDGV MAFSRSETED RRQ
Genome annotation databases
Ensembli | ENSACAT00000013209; ENSACAP00000012950; ENSACAG00000013203 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000012950 |
Genome annotation databases
Ensembli | ENSACAT00000013209; ENSACAP00000012950; ENSACAG00000013203 |
Phylogenomic databases
eggNOGi | ENOG502S3XR, Eukaryota |
GeneTreei | ENSGT00940000161133 |
HOGENOMi | CLU_145119_1_0_1 |
InParanoidi | H9GJP8 |
OMAi | SHEEMYI |
Gene expression databases
Bgeei | ENSACAG00000013203, Expressed in brain and 15 other tissues |
Family and domain databases
Gene3Di | 1.10.10.490, 1 hit |
InterProi | View protein in InterPro IPR042999, CTNNBIP1 IPR009428, ICAT_dom IPR036911, ICAT_sf |
PANTHERi | PTHR47142, PTHR47142, 1 hit |
Pfami | View protein in Pfam PF06384, ICAT, 1 hit |
SUPFAMi | SSF81730, SSF81730, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GJP8_ANOCA | |
Accessioni | H9GJP8Primary (citable) accession number: H9GJP8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | May 16, 2012 | |
Last modified: | August 12, 2020 | |
This is version 41 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |