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Entry version 47 (12 Aug 2020)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

SORBS1

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SORBS1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000012338, Expressed in testis and 13 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000012232

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini174 – 231SoHoInterPro annotationAdd BLAST58
Domaini1022 – 1081SH3InterPro annotationAdd BLAST60
Domaini1096 – 1157SH3InterPro annotationAdd BLAST62
Domaini1203 – 1265SH3InterPro annotationAdd BLAST63

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni30 – 77DisorderedSequence analysisAdd BLAST48
Regioni228 – 286DisorderedSequence analysisAdd BLAST59
Regioni435 – 455DisorderedSequence analysisAdd BLAST21

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili963 – 989Sequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi30 – 50PolarSequence analysisAdd BLAST21
Compositional biasi62 – 76PolarSequence analysisAdd BLAST15
Compositional biasi228 – 244PolarSequence analysisAdd BLAST17
Compositional biasi439 – 453PolarSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4225, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158658

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003951_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H9GIX7

TreeFam database of animal gene trees

More...
TreeFami
TF320680

Family and domain databases

Conserved Domains Database

More...
CDDi
cd11922, SH3_Sorbs1_2, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR003127, SoHo_dom
IPR035611, SORBS1_SH3_2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00018, SH3_1, 1 hit
PF07653, SH3_2, 1 hit
PF14604, SH3_9, 1 hit
PF02208, Sorb, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00452, SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00326, SH3, 3 hits
SM00459, Sorb, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50044, SSF50044, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50002, SH3, 3 hits
PS50831, SOHO, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GIX7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSTNGQKRD VDTAKVCTGK GAVTLWASPA HEENLNTSYT SSQDIQLSES
60 70 80 90 100
AEPGKQEIDD ILPSVGSNTD AQSSPLAAKG YRSVRPNFFE STSHEPCPQL
110 120 130 140 150
YEAPRTSSGT ECYGPLTVAS KHSSAYPSTT IVNPTIVLLQ HNRAPESVPD
160 170 180 190 200
APVLDKVDSI PTQEKISQWK KQDGTRVTEY EADHSLDDIG IPLRNTDRSK
210 220 230 240 250
DWYKTMFKQI HRLTKDEDSD SCVPQYSFYK DTRSQNSVPR SKSENDTNTP
260 270 280 290 300
EKVVRRSATL PLPARSSSLK GSVERNDWEP PDKKVDTRKY YAEPKSIYEY
310 320 330 340 350
QPGKSSFLDN EHLTRDISLE EIDLKDEPWY KFFSELEFGK PTDPEKELYL
360 370 380 390 400
YRTELEADTE KIENLDKVPD KEPVKSTAHS SSMEILSDHL AHSPYSPNSH
410 420 430 440 450
LVQREFTDTI GDSTGLETER QIYKSVLEGG DIPLQGLSGL KRPSSSASTK
460 470 480 490 500
VDRKGGNAHT IARSSVYNQS FNFSNAGQLG QFCKYKKPLS VAKVCIAEIL
510 520 530 540 550
PSKFKPKRAT PPIPRLDKKD LLPHEKTQSC ENLHSSLTFF GNKKNSVIDV
560 570 580 590 600
DASFENILMK SKQQSAVKSS STQSLRECGS SSFRKEYMLG SQKNSMEFAM
610 620 630 640 650
LYKDMHHINR SGFQRGVISS GSVKEIASHF ECEFKSKREP SLSPNRENLE
660 670 680 690 700
QIPKHTVSSR ITAFEMLIQK SLSMPALSFS STHNKSPTPS LSNSCLNSIY
710 720 730 740 750
SAEYELDLSM PVLREKNLSD LTNLADTSSH SYSNIEDTSS EFSNMTPIDT
760 770 780 790 800
LSACPDEIDV ISNKSNDSGG DSSISIAQKY KVNKCKGSCP ASYTRFTTMR
810 820 830 840 850
RHEQQQPAQG DVEGEKHLLP RNIYLMSPLP FRLKKPLQRH SRTTLPLPGL
860 870 880 890 900
GALLASTCEI QNDQLCMQRK PPAPKRLSSC DIVKRFSHFL EVETWQTSSV
910 920 930 940 950
SLLDFPDVFN NANVPYALYY KVDTNNNPQK EFRTYPGVDS ESPRHFPPLD
960 970 980 990 1000
YMENPEDIFH RRHSDKEKLL EDQRRLKREQ EEADIAARRH TGVIPTHHQF
1010 1020 1030 1040 1050
ITNERFGDLL IVDDTAKRKS GSEMRAARAR FDFKAQTLKE LPLQKGDIVY
1060 1070 1080 1090 1100
IYKEIDQNWY EGEHHGRVGI FPQSYVELLP PREKHQPKKP SQLQVLEYGD
1110 1120 1130 1140 1150
AIAKFNFNGD TQVEMSFRKG ERITLIRQVD ENWYEGKILG TNRQGIFPVT
1160 1170 1180 1190 1200
YVDIFKQPVV KNMEDHSDLL FSHSMNHSQA TSPQQPPKVP LLESTIERNH
1210 1220 1230 1240 1250
TAQNVLSYRA LYSYIPQNDD ELELRDGDII DVMEKCDDGW FVVGTSRRTQ
1260
QFGTFPGNYV KLLSL
Length:1,265
Mass (Da):143,239
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC88E1F062B7516F9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAWZ02023808 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000012482; ENSACAP00000012232; ENSACAG00000012338

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02023808 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000012232

Genome annotation databases

EnsembliENSACAT00000012482; ENSACAP00000012232; ENSACAG00000012338

Phylogenomic databases

eggNOGiKOG4225, Eukaryota
GeneTreeiENSGT00940000158658
HOGENOMiCLU_003951_1_1_1
InParanoidiH9GIX7
TreeFamiTF320680

Gene expression databases

BgeeiENSACAG00000012338, Expressed in testis and 13 other tissues

Family and domain databases

CDDicd11922, SH3_Sorbs1_2, 1 hit
InterProiView protein in InterPro
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR003127, SoHo_dom
IPR035611, SORBS1_SH3_2
PfamiView protein in Pfam
PF00018, SH3_1, 1 hit
PF07653, SH3_2, 1 hit
PF14604, SH3_9, 1 hit
PF02208, Sorb, 1 hit
PRINTSiPR00452, SH3DOMAIN
SMARTiView protein in SMART
SM00326, SH3, 3 hits
SM00459, Sorb, 1 hit
SUPFAMiSSF50044, SSF50044, 3 hits
PROSITEiView protein in PROSITE
PS50002, SH3, 3 hits
PS50831, SOHO, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GIX7_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GIX7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: June 26, 2013
Last modified: August 12, 2020
This is version 47 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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