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UniProtKB - H9GIT0 (H9GIT0_ANOCA)

Entry version 51 (10 Feb 2021)
Sequence version 1 (16 May 2012)
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Protein

Vitellogenin domain-containing protein

Gene

MTTP

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransportARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vitellogenin domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTTPImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500362074422 – 892Vitellogenin domain-containing proteinSequence analysisAdd BLAST871

Keywords - PTMi

Disulfide bondARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000012194, Expressed in liver and 11 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000012114

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini28 – 662VitellogeninInterPro annotationAdd BLAST635

Keywords - Domaini

SignalSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4337, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011412

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_014703_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		H9GIT0

Identification of Orthologs from Complete Genome Data

More...OMAi		YRVFELE

Database of Orthologous Groups

More...OrthoDBi		673565at2759

TreeFam database of animal gene trees

More...TreeFami		TF328754

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.20, 1 hit
2.30.230.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR015819, Lipid_transp_b-sht_shell
IPR001747, Lipid_transpt_N
IPR011030, Lipovitellin_superhlx_dom
IPR039988, MTTP
IPR015816, Vitellinogen_b-sht_N

The PANTHER Classification System

More...PANTHERi		PTHR13024, PTHR13024, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01347, Vitellogenin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00638, LPD_N, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48431, SSF48431, 1 hit
SSF56968, SSF56968, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51211, VITELLOGENIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GIT0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILLTVLFPC IISTYSASVK GHNTGPRINN DKLYKFAYST EVLIDRVKGA 
        60         70         80         90        100
PQESAGYQIS SEVDVNLVWR NPNNDDDQLI KIAIQNVAVE NVNERPPGKN 
       110        120        130        140        150
VFKGKKTDVV IEKEQLIALK RPVVLHWIRG KIKTFYSYEK EPAVIQNLKR 
       160        170        180        190        200
GLASLFQIQL HSGTTSEVDI CGKCNVTYQA RENQLTKIKA CKLERMGFTS 
       210        220        230        240        250
QNQIFDISKK SSSATIYVLE DTFIKSVRAE ENHILKANIH RTSDAKIVSK 
       260        270        280        290        300
QKMELKSTEG GPRMMAGKQV ASIVKALDSN YVAVSLMAEP ASDECRNCPS 
       310        320        330        340        350
LSQQWENIRK QLEPENLSKA DAVRGFLYFI QNLRKATKEE ILQILRSERN 
       360        370        380        390        400
IGILPQLVDA VASAQTSASL GAMLDFLDFK NKNGSVLQER FLYASGFASH 
       410        420        430        440        450
PNEFLLKSLI NTYNSQIGST EIREMVVIIT GALIRKLCDR GGCKLPAVVE 
       460        470        480        490        500
AKKLIFGGLN RAEKADDVKV YLLALKNALL PEAIPVLLKY AESGEGPIST 
       510        520        530        540        550
VAVTALQRYD YSFINSEVKK TMNRIYHQNR KVHEKTVRVT AAAIIFSNNP 
       560        570        580        590        600
SFMEVKNLLL SIGELPLEMN KYMLSLVQDI LRFEMPASKM IRSVLKDMLI 
       610        620        630        640        650
HNYDRFSKLG SSSAFSGHLK RGPDVSSTYS LDILYSGSGI FRRSNMNILL 
       660        670        680        690        700
FNNFARLLAT KVVLEAQGLE SLIAANADEG EENLESFAGV SAIVCDVQLR 
       710        720        730        740        750
PVTFFQGYGD LMSKMFSATG DPVNVLKGLI LLMDYSQVIQ LQSGLTCSTE 
       760        770        780        790        800
FQGGIAIDVS GGIEFSLWYR ESKTYVKTRG AVAIVGNIVV DASFVKAGME 
       810        820        830        840        850
TSSEVEATLD VRTTVQFSQY PFLVCIRMDR TDTPFRQFVT KYEGLTPGKP 
       860        870        880        890 
YVTRKGKVGL LDGSEYPLHQ ENSHMCRKVF SDQSDSSSES WF
Length:892
Mass (Da):99,388
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4290C44F6DFD1652
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAWZ02024877 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		XP_003225781.1, XM_003225733.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000012359; ENSACAP00000012114; ENSACAG00000012194

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100552347

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		acs:100552347

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02024877 Genomic DNA No translation available.
RefSeqiXP_003225781.1, XM_003225733.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000012114

Genome annotation databases

EnsembliENSACAT00000012359; ENSACAP00000012114; ENSACAG00000012194
GeneIDi100552347
KEGGiacs:100552347

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		4547

Phylogenomic databases

eggNOGiKOG4337, Eukaryota
GeneTreeiENSGT00390000011412
HOGENOMiCLU_014703_0_0_1
InParanoidiH9GIT0
OMAiYRVFELE
OrthoDBi673565at2759
TreeFamiTF328754

Gene expression databases

BgeeiENSACAG00000012194, Expressed in liver and 11 other tissues

Family and domain databases

Gene3Di1.25.10.20, 1 hit
2.30.230.10, 1 hit
InterProiView protein in InterPro
IPR015819, Lipid_transp_b-sht_shell
IPR001747, Lipid_transpt_N
IPR011030, Lipovitellin_superhlx_dom
IPR039988, MTTP
IPR015816, Vitellinogen_b-sht_N
PANTHERiPTHR13024, PTHR13024, 1 hit
PfamiView protein in Pfam
PF01347, Vitellogenin_N, 1 hit
SMARTiView protein in SMART
SM00638, LPD_N, 1 hit
SUPFAMiSSF48431, SSF48431, 1 hit
SSF56968, SSF56968, 1 hit
PROSITEiView protein in PROSITE
PS51211, VITELLOGENIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GIT0_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GIT0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: February 10, 2021
This is version 51 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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