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UniProtKB - H9GIM5 (H9GIM5_ANOCA)
Protein
Submitted name:
Forkhead box N1
Gene
FOXN1
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 236 – 332 | Fork-headPROSITE-ProRule annotationAdd BLAST | 97 |
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- transcription cis-regulatory region binding Source: GO_Central
GO - Biological processi
- blood vessel morphogenesis Source: Ensembl
- keratinocyte differentiation Source: Ensembl
- lymphoid lineage cell migration into thymus Source: Ensembl
- nail development Source: Ensembl
- positive regulation of epithelial cell differentiation Source: Ensembl
- positive regulation of hair follicle development Source: Ensembl
- regulation of positive thymic T cell selection Source: Ensembl
- regulation of transcription by RNA polymerase II Source: GO_Central
- T cell homeostasis Source: Ensembl
- T cell lineage commitment Source: Ensembl
- thymus epithelium morphogenesis Source: Ensembl
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Forkhead box N1Imported |
Gene namesi | Name:FOXN1Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationExpressioni
Gene expression databases
Bgeei | ENSACAG00000012187, Expressed in dewlap and 2 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 236 – 332 | Fork-headInterPro annotationAdd BLAST | 97 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 79 | DisorderedSequence analysisAdd BLAST | 79 | |
Regioni | 339 – 399 | DisorderedSequence analysisAdd BLAST | 61 | |
Regioni | 463 – 483 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 53 – 70 | Polar residuesSequence analysisAdd BLAST | 18 |
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000158029 |
HOGENOMi | CLU_031768_0_0_1 |
InParanoidi | H9GIM5 |
TreeFami | TF329867 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
i Sequence
Sequence statusi: Complete.
H9GIM5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVSLLQDQAN IAFSENHPHR DRMQSHEDVG SPIQQEGPNF CHQPHDGDNG
60 70 80 90 100
VERSQSESSS PSSSPPENNL YGVFPSGAHR YGYEDPPRAG FLRTPFQAFK
110 120 130 140 150
RQFAEEGDPL GVAEGVPPFK AASMEQTYEG PETEMYLAGP EPGWGKGLPY
160 170 180 190 200
GHPGQGLPPT SMDPDVKLKP PSLDDPPGLY CYQPQMPPMY CPSHPFHQYP
210 220 230 240 250
TGSGSYPVTY ISTSHYPYQR IAPQGPPEHH QPLFPKPIYS YSILIFMALR
260 270 280 290 300
NSKTGSLPVS EIYNFMTEHF PYFKTAPDGW KNSVRHNLSL NKCFEKVENK
310 320 330 340 350
SGSSSRKGCL WALNPAKIEK MQEELQKWKR KDPIAVRKSM AKPEELDTLI
360 370 380 390 400
GGKAEKPRPP LMAGGNPSGV GSRQVPLLHP SQHGPRGQDS PVPAQSPKVL
410 420 430 440 450
EGPRSVQDVL VPDGDLSSDL DALNPSLTDF DLQGNLWEEL KDDSLTTDPL
460 470 480 490 500
ALVSSSPCFS GQMDDNGAST DNNNNGGNSH CNTQHHGLPE IQLTTLYSAF
510 520
MELDTGSTPF LNSLGAKPIA LV
Sequence databases
RefSeqi | XP_016852829.1, XM_016997340.1 |
Genome annotation databases
Ensembli | ENSACAT00000012197; ENSACAP00000011953; ENSACAG00000012187 |
GeneIDi | 103277528 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_016852829.1, XM_016997340.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000011953 |
Genome annotation databases
Ensembli | ENSACAT00000012197; ENSACAP00000011953; ENSACAG00000012187 |
GeneIDi | 103277528 |
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000158029 |
HOGENOMi | CLU_031768_0_0_1 |
InParanoidi | H9GIM5 |
TreeFami | TF329867 |
Gene expression databases
Bgeei | ENSACAG00000012187, Expressed in dewlap and 2 other tissues |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GIM5_ANOCA | |
Accessioni | H9GIM5Primary (citable) accession number: H9GIM5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | September 29, 2021 | |
Last modified: | January 19, 2022 | |
This is version 66 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |