UniProtKB - H9GIC3 (H9GIC3_ANOCA)
Protein
Submitted name:
Uncharacterized protein
Gene
PHLPP1
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- protein serine/threonine phosphatase activity Source: GO_Central
GO - Biological processi
- entrainment of circadian clock Source: Ensembl
- negative regulation of protein kinase B signaling Source: Ensembl
- regulation of apoptotic process Source: Ensembl
- regulation of JNK cascade Source: Ensembl
- regulation of p38MAPK cascade Source: Ensembl
- regulation of T cell anergy Source: Ensembl
- signal transduction Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:PHLPP1Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Other locations
- cytoplasm Source: GO_Central
- intracellular membrane-bounded organelle Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000011864, Expressed in female gonad and 14 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 143 | PHInterPro annotationAdd BLAST | 101 | |
Domaini | 682 – 929 | PPM-type phosphataseInterPro annotationAdd BLAST | 248 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 965 – 1006 | DisorderedSequence analysisAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 968 – 1006 | PolarSequence analysisAdd BLAST | 39 |
Keywords - Domaini
Leucine-rich repeatARBA annotation, RepeatARBA annotationPhylogenomic databases
eggNOGi | KOG0618, Eukaryota |
GeneTreei | ENSGT00940000158137 |
HOGENOMi | CLU_003020_0_0_1 |
InParanoidi | H9GIC3 |
OMAi | LDICGYF |
TreeFami | TF315993 |
Family and domain databases
CDDi | cd00143, PP2Cc, 1 hit |
Gene3Di | 2.30.29.30, 1 hit 3.60.40.10, 1 hit 3.80.10.10, 3 hits |
InterProi | View protein in InterPro IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR036457, PPM-type_dom_sf IPR001932, PPM-type_phosphatase_dom |
Pfami | View protein in Pfam PF00560, LRR_1, 1 hit PF13855, LRR_8, 3 hits PF00481, PP2C, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 10 hits SM00332, PP2Cc, 1 hit |
SUPFAMi | SSF81606, SSF81606, 1 hit |
PROSITEi | View protein in PROSITE PS51450, LRR, 17 hits PS50003, PH_DOMAIN, 1 hit PS51746, PPM_2, 1 hit |
i Sequence
Sequence statusi: Complete.
H9GIC3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
HSFWFQIGYN KMGQSQESGL KKEIKLLAVS ISGKPHSIGN SERIQLSGMY
60 70 80 90 100
NVRKGKMHLP VNRWTRRQVI LCGTCLIVSS VKESQTGKMH VLPLIGGKVE
110 120 130 140 150
EVKKHQHCLA FSSSGPQSQS YYICFDTFTE YLRWLRQASK IASQRISSVD
160 170 180 190 200
LSCCSLEDLP ANLFYSQDLT HLNLKQNFLR LNPNSSSSRG LNELQRFSKL
210 220 230 240 250
RSLNLSNNHL GEFPLAVCSI PTLTELNVSC NALKNIPVAV GDMNNLQTFL
260 270 280 290 300
LDGNFLQSLP VELERMHQLS YLGLSFNEFT DIPEILEKLP AMDKLCMSGN
310 320 330 340 350
CLETLNLQTL RRMPHIKHID LRLNVIRRLV TDKADFLHHV TQLDLRDNKL
360 370 380 390 400
GELDATIFNN VEILHCERNQ LVTLKISGYL LKALYATANE LVHLDVYPVP
410 420 430 440 450
NYLTYMDVSR NHLESLPEWV CDSRKLEVLD LGHNQIRELP ARLFCNISLR
460 470 480 490 500
KLLAGHNQLA RLPERIERTH VEVLDVQHNL LTELPSNLLL KADSLRYLNA
510 520 530 540 550
SANKLEMLPP ATLSEETCSI LQELYLTNNH LTDKCVPLLT GHPHLKILHM
560 570 580 590 600
AYNRLQSFPA SKMAKLEELE EIDVSGNKLK SIPTTIMNCR RMHTVIAHSN
610 620 630 640 650
CIEVFPEVMQ LGEIKCVDLS CNELTEVTLP ENLPPKLQEL DLTGNPRLVL
660 670 680 690 700
DHKTLELLNN IRCFKIDQPS AGDASGAPAV WSHGYTEASG VKNKLCVAAL
710 720 730 740 750
SANNFCENRE ALYGVFDGDR NVEVPYLLQC TMSDILAEEL QKTKSEEEYM
760 770 780 790 800
INTFIVMQRK LGTAGQKLGG SAVLCHIKHD PIDPGGCFTL TSANVGKCQS
810 820 830 840 850
VLCRNGKPLP LSRSYMISCE EELRRIKQHK AIITEDGKVN GVTDSTRILG
860 870 880 890 900
YTFLHPSVIP RPHVQSITLT PQDEFFILGS KGLWDSLSIE EAVEAVRNVP
910 920 930 940 950
DALGAAKKLC TLAQSYGCND SLSAVVVQLN VTEDSFCCCE LNGVPPPSPG
960 970 980 990 1000
IFPQSVNVVI KDKPSDGLGM PSSSSGVASE ISSEISTSEM SSEVGSTASD
1010 1020 1030 1040 1050
EPPQVTMNEN SPAYPSEQRC MLHPVCLSNS FQRQLSSATF SSAFSDNGLD
1060 1070 1080 1090 1100
SDDEEPIEGV FSNGSRVEVE VDIHCGRAKE KQQLLTQAPM EASDEGIVIN
1110 1120 1130 1140 1150
TNEDEVCLLR KGDLSATGTI GRRRGNGSVA PQERSHNLIE VAADAPLRKT
1160 1170 1180 1190
GGYFAAPAQP DPDDQFIIPP ELEEEVKEII IMTRHYDQAS QNKVMRQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02022555 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSACAT00000011983; ENSACAP00000011740; ENSACAG00000011864 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02022555 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000011740 |
Genome annotation databases
Ensembli | ENSACAT00000011983; ENSACAP00000011740; ENSACAG00000011864 |
Phylogenomic databases
eggNOGi | KOG0618, Eukaryota |
GeneTreei | ENSGT00940000158137 |
HOGENOMi | CLU_003020_0_0_1 |
InParanoidi | H9GIC3 |
OMAi | LDICGYF |
TreeFami | TF315993 |
Gene expression databases
Bgeei | ENSACAG00000011864, Expressed in female gonad and 14 other tissues |
Family and domain databases
CDDi | cd00143, PP2Cc, 1 hit |
Gene3Di | 2.30.29.30, 1 hit 3.60.40.10, 1 hit 3.80.10.10, 3 hits |
InterProi | View protein in InterPro IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR036457, PPM-type_dom_sf IPR001932, PPM-type_phosphatase_dom |
Pfami | View protein in Pfam PF00560, LRR_1, 1 hit PF13855, LRR_8, 3 hits PF00481, PP2C, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 10 hits SM00332, PP2Cc, 1 hit |
SUPFAMi | SSF81606, SSF81606, 1 hit |
PROSITEi | View protein in PROSITE PS51450, LRR, 17 hits PS50003, PH_DOMAIN, 1 hit PS51746, PPM_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GIC3_ANOCA | |
Accessioni | H9GIC3Primary (citable) accession number: H9GIC3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | May 16, 2012 | |
Last modified: | October 7, 2020 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |