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Entry version 43 (07 Oct 2020)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi54 ↔ 118PROSITE-ProRule annotation
Disulfide bondi67 ↔ 128PROSITE-ProRule annotation
Disulfide bondi98 ↔ 108PROSITE-ProRule annotation
Disulfide bondi157 ↔ 221PROSITE-ProRule annotation
Disulfide bondi170 ↔ 231PROSITE-ProRule annotation
Disulfide bondi201 ↔ 211PROSITE-ProRule annotation
Disulfide bondi264 ↔ 328PROSITE-ProRule annotation
Disulfide bondi277 ↔ 338PROSITE-ProRule annotation
Disulfide bondi308 ↔ 318PROSITE-ProRule annotation
Disulfide bondi399 ↔ 463PROSITE-ProRule annotation
Disulfide bondi412 ↔ 473PROSITE-ProRule annotation
Disulfide bondi443 ↔ 453PROSITE-ProRule annotation
Disulfide bondi505 ↔ 569PROSITE-ProRule annotation
Disulfide bondi518 ↔ 579PROSITE-ProRule annotation
Disulfide bondi549 ↔ 559PROSITE-ProRule annotation
Disulfide bondi610 ↔ 674PROSITE-ProRule annotation
Disulfide bondi623 ↔ 684PROSITE-ProRule annotation
Disulfide bondi654 ↔ 664PROSITE-ProRule annotation
Disulfide bondi713 ↔ 777PROSITE-ProRule annotation
Disulfide bondi726 ↔ 787PROSITE-ProRule annotation
Disulfide bondi757 ↔ 767PROSITE-ProRule annotation
Disulfide bondi816 ↔ 880PROSITE-ProRule annotation
Disulfide bondi829 ↔ 890PROSITE-ProRule annotation
Disulfide bondi860 ↔ 870PROSITE-ProRule annotation
Disulfide bondi953 ↔ 1017PROSITE-ProRule annotation
Disulfide bondi966 ↔ 1027PROSITE-ProRule annotation
Disulfide bondi997 ↔ 1007PROSITE-ProRule annotation
Disulfide bondi1102 ↔ 1112PROSITE-ProRule annotation
Disulfide bondi1175 ↔ 1239PROSITE-ProRule annotation
Disulfide bondi1188 ↔ 1249PROSITE-ProRule annotation
Disulfide bondi1219 ↔ 1229PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000010950, Expressed in female gonad and 1 other tissue

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 27SRCRInterPro annotationAdd BLAST27
Domaini29 – 129SRCRInterPro annotationAdd BLAST101
Domaini132 – 232SRCRInterPro annotationAdd BLAST101
Domaini239 – 339SRCRInterPro annotationAdd BLAST101
Domaini374 – 474SRCRInterPro annotationAdd BLAST101
Domaini480 – 580SRCRInterPro annotationAdd BLAST101
Domaini585 – 685SRCRInterPro annotationAdd BLAST101
Domaini688 – 788SRCRInterPro annotationAdd BLAST101
Domaini791 – 891SRCRInterPro annotationAdd BLAST101
Domaini928 – 1028SRCRInterPro annotationAdd BLAST101
Domaini1033 – 1131SRCRInterPro annotationAdd BLAST99
Domaini1150 – 1250SRCRInterPro annotationAdd BLAST101

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQ5W, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163299

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_258747_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H9GH12

TreeFam database of animal gene trees

More...
TreeFami
TF329295

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.250.10, 11 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001190, SRCR
IPR017448, SRCR-like_dom
IPR036772, SRCR-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00530, SRCR, 11 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00258, SPERACTRCPTR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00202, SR, 11 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56487, SSF56487, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00420, SRCR_1, 10 hits
PS50287, SRCR_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GH12-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSFRYCDLNA LEEHSCTHEE DAGVICARTR LVNGPNRCSG RVEMLLNGLW
60 70 80 90 100
GTVCDDGWDL SDAQVVCREL GCGEAVSAPE GAHFGKGNGT IWIHNAECLG
110 120 130 140 150
TEVALWDCKK AMHESYECRH EEDAGVVCSE DLHLMNGTSP CSGRVEVFHN
160 170 180 190 200
DAWGTICDAG WDLQDAQVVC SQLGCGKASK ALGGAHYGQG SGPIWLESIN
210 220 230 240 250
CTGEEASLKE CQKGGWGEHS CSHSQDASVE CSESDHMEIR LEGGPNLCSG
260 270 280 290 300
RVEVFISGEW TSVCDDSWGI EEAMVVCRQL GCGSAVSATH EAQFGNGNVS
310 320 330 340 350
IGLDDVRCGG TESTLSECPA SPWGEHDCSR EETAGVVCSE NRILVELEKA
360 370 380 390 400
LLEPAKQTAK QSSQPSFISP ESEVRLVDGL TPCTGRVEVF HNKGWGTVCD
410 420 430 440 450
NGWDLEDARV VCQEVGCGKA LVAATGARFG QGSGPIWMNQ INCTGKENVL
460 470 480 490 500
KKCPQEKSFN LTCDHRKDAG VECAAFLREL RLVNGSSNCS GRVEVFHNET
510 520 530 540 550
WGTICDAGWD LQDAQVVCRE LGCGEALSAS GGAQFGRGAG PIWLEGMSCI
560 570 580 590 600
GKEESLRQCP KGQWGEHSCD HSRDASVECT DPRKIRLVNG FSRCSGRIEV
610 620 630 640 650
FQNQEWGTLC DFEWDLNDAR VLCKELGCGD VISVPWGAHF GQGSGPIWLE
660 670 680 690 700
NVNCTGEEIA LAECPKSPWG KHSCNHSQDV NVECSAEAHL VNGTNRCSGR
710 720 730 740 750
VELFHNKQWG TVCDAGWDTY DAQVVCRELG CGNALKAFRG AHHGQGFGPI
760 770 780 790 800
WLEGVNCTGK ETSLRECPQN PWGEHHCNHS QDASVECTGW IRLINGSSHC
810 820 830 840 850
SGTVEVLHNQ HWKAICDKNW GLYEEHVVCR EMGCKQIPWN PRSARLLSKY
860 870 880 890 900
RVNRLSIPFC KWTANDLAEC NLTDFKEESC SHGRTVAVTC SGNPCKQLPQ
910 920 930 940 950
YHAPVVTQLG RLLQATSLPM FYTTIEDLRL LNGTSPCSGR VEVFHNDTWG
960 970 980 990 1000
TICDAGWDLQ DAQVVCSQLG CGKASKALGG AHYGQGSGPI WLESINCRGE
1010 1020 1030 1040 1050
ESSLKECQKG GWGEHSCSHS QDASVECSDF TRTRLVNGTN GCSGRVEVFL
1060 1070 1080 1090 1100
NGEWGSVCDD QWDLSDAQVV CRELGCGGAV LTLGEAHFGK GNGPIWIDEA
1110 1120 1130 1140 1150
KCLGREATLQ KCPFERKHDC SHEEDAGVVC SGQTVQVFWT CDNMKDSENL
1160 1170 1180 1190 1200
RLMNGTSPCS GRVEVFHNDT WGTICDAGWD LQDAQVVCSQ LGCGKASKAL
1210 1220 1230 1240 1250
GGAHYGQGSG PIWLENINCT GEEASLKECQ KGIWGEHSCS HSQDASVECS

GTCLPQ
Length:1,256
Mass (Da):136,124
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1F2661272774ED2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAWZ02031078 Genomic DNA No translation available.
AAWZ02031079 Genomic DNA No translation available.
AAWZ02031080 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000010974; ENSACAP00000010751; ENSACAG00000010950

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02031078 Genomic DNA No translation available.
AAWZ02031079 Genomic DNA No translation available.
AAWZ02031080 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSACAT00000010974; ENSACAP00000010751; ENSACAG00000010950

Phylogenomic databases

eggNOGiENOG502QQ5W, Eukaryota
GeneTreeiENSGT00940000163299
HOGENOMiCLU_258747_0_0_1
InParanoidiH9GH12
TreeFamiTF329295

Gene expression databases

BgeeiENSACAG00000010950, Expressed in female gonad and 1 other tissue

Family and domain databases

Gene3Di3.10.250.10, 11 hits
InterProiView protein in InterPro
IPR001190, SRCR
IPR017448, SRCR-like_dom
IPR036772, SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530, SRCR, 11 hits
PRINTSiPR00258, SPERACTRCPTR
SMARTiView protein in SMART
SM00202, SR, 11 hits
SUPFAMiSSF56487, SSF56487, 11 hits
PROSITEiView protein in PROSITE
PS00420, SRCR_1, 10 hits
PS50287, SRCR_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GH12_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GH12
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: June 26, 2013
Last modified: October 7, 2020
This is version 43 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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