UniProtKB - H9GH00 (H9GH00_ANOCA)
Protein
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
Gene
ndufb8
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.UniRule annotation
GO - Molecular functioni
- NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-UniRule
GO - Biological processi
- mitochondrial electron transport, NADH to ubiquinone Source: UniProtKB-UniRule
Keywordsi
Biological process | Electron transport, Respiratory chainUniRule annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrialUniRule annotationAlternative name(s): Complex I-ASHIUniRule annotation NADH-ubiquinone oxidoreductase ASHI subunitUniRule annotation |
Gene namesi | Name:ndufb8Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane UniRule annotation
Mitochondrion
- mitochondrial respiratory chain complex I Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 137 – 157 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotationExpressioni
Gene expression databases
Bgeei | ENSACAG00000010928, Expressed in heart and 15 other tissues |
Interactioni
Subunit structurei
Complex I is composed of 45 different subunits.
UniRule annotationARBA annotationProtein-protein interaction databases
STRINGi | 28377.ENSACAP00000010733 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG4040, Eukaryota |
GeneTreei | ENSGT00390000000628 |
HOGENOMi | CLU_108654_1_0_1 |
InParanoidi | H9GH00 |
OrthoDBi | 1427659at2759 |
TreeFami | TF317319 |
Family and domain databases
InterProi | View protein in InterPro IPR008699, NDUFB8 IPR016551, Ndufb8_metazoa |
PANTHERi | PTHR12840, PTHR12840, 1 hit |
Pfami | View protein in Pfam PF05821, NDUF_B8, 1 hit |
PIRSFi | PIRSF009288, NDUB8, 1 hit |
i Sequence
Sequence statusi: Complete.
H9GH00-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALVAFRGAL RPSALPRSSW RWKAAAPLGA RAASDLSKDM LPGPYPKTPE
60 70 80 90 100
ERAAAARKYN MRVEDYEPYP DEGFGYGDYP KLPDRSQQER DPWYEWDHSD
110 120 130 140 150
LRRNHGETMH WDFDMFLRTR VDTSPTPISW RTMRISLFSF IGFMLVMFVL
160 170 180 190
GEMYPSYRPV GPKQYPYNDL YLERGGDPKQ PPPEVKHYEI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02026764 Genomic DNA No translation available. |
RefSeqi | XP_003226593.1, XM_003226545.3 |
Genome annotation databases
Ensembli | ENSACAT00000010955; ENSACAP00000010733; ENSACAG00000010928 |
GeneIDi | 100564672 |
KEGGi | acs:100564672 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02026764 Genomic DNA No translation available. |
RefSeqi | XP_003226593.1, XM_003226545.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000010733 |
Genome annotation databases
Ensembli | ENSACAT00000010955; ENSACAP00000010733; ENSACAG00000010928 |
GeneIDi | 100564672 |
KEGGi | acs:100564672 |
Organism-specific databases
CTDi | 4714 |
Phylogenomic databases
eggNOGi | KOG4040, Eukaryota |
GeneTreei | ENSGT00390000000628 |
HOGENOMi | CLU_108654_1_0_1 |
InParanoidi | H9GH00 |
OrthoDBi | 1427659at2759 |
TreeFami | TF317319 |
Gene expression databases
Bgeei | ENSACAG00000010928, Expressed in heart and 15 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR008699, NDUFB8 IPR016551, Ndufb8_metazoa |
PANTHERi | PTHR12840, PTHR12840, 1 hit |
Pfami | View protein in Pfam PF05821, NDUF_B8, 1 hit |
PIRSFi | PIRSF009288, NDUB8, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GH00_ANOCA | |
Accessioni | H9GH00Primary (citable) accession number: H9GH00 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | June 26, 2013 | |
Last modified: | December 2, 2020 | |
This is version 41 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |