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Entry version 52 (29 Sep 2021)
Sequence version 2 (29 Sep 2021)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000010850, Expressed in brain and 10 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

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STRINGi
28377.ENSACAP00000010660

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG0507, Eukaryota

Ensembl GeneTree

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GeneTreei
ENSGT00940000158025

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
CLU_003619_1_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
H9GGW2

Identification of Orthologs from Complete Genome Data

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OMAi
HRESPGY

TreeFam database of animal gene trees

More...
TreeFami
TF320582

Family and domain databases

Conserved Domains Database

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CDDi
cd09497, SAM_caskin1_2_repeat1, 1 hit
cd09498, SAM_caskin1_2_repeat2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.10.150.50, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027013, Caskin-1/2
IPR035497, Caskin1/2_SAM_1
IPR035498, Caskin1/2_SAM_2
IPR032117, Caskin_C
IPR001660, SAM
IPR013761, SAM/pointed_sf

The PANTHER Classification System

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PANTHERi
PTHR24174:SF11, PTHR24174:SF11, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF16632, Caskin-tail, 1 hit
PF00536, SAM_1, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00454, SAM, 2 hits

Superfamily database of structural and functional annotation

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SUPFAMi
SSF47769, SSF47769, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50105, SAM_DOMAIN, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GGW2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LGGSSFQSQP YGEQQPKKVE PMSEGKSSEA VYQWLCKFQL QLYAPHFINA
60 70 80 90 100
GYDIPTISRM TPEDLTAIGV TKPGHRKKIA SEINSLNISE WLPEYKPANL
110 120 130 140 150
SLWLSMIGLA QYYKVLVENG YENIDFITDI TWEDLQEIGI TKLGHQKKLM
160 170 180 190 200
LAVKKLAEIQ KAEFAKYESG TLKKKGPPQD TVAIESPQQE SAECQSPKMT
210 220 230 240 250
TFQDSELSNE LQVAMTGEEG PEKQGNHVGH FREGTAYRHG PRLSHENSLS
260 270 280 290 300
GRAKQMSSSQ ELLGDGPKPS SGAMSKSQEY LVEDGKESSA TLPKEVRTLR
310 320 330 340 350
HGHSVKRASV PPVPGKPRQS FPPSAGRYTP PQTPTKPRPS SPQTLGMPHA
360 370 380 390 400
KVKPTPQLLP QSDCPMSPRS LPQSPTHRGF AYVMPQPVEG DGHATGPLAQ
410 420 430 440 450
AVPVLPVSVP VLCLPPQAAD SEEEAGRPKK RAHSLNRYTV SDSEQERDEL
460 470 480 490 500
LVPDAGPYAT VQRRVGRSHS VRAQSGGDKN VNRSQSFAVR PKKKGPPPPP
510 520 530 540 550
PKRSSSAISS TNMSDDFTKE GEEGLEPPEE QQQQRRASDS GSVVDTGSAG
560 570 580 590 600
SVKSIAAMLE MSSIGGGGRA LHPVSPDHAR VATVMASVKH KDAIGPDGEV
610 620 630 640 650
VNRRRTISGP VTGLVAAARR DPRAEHGGGP PQNASGENIP FAEEGSLTIR
660 670 680 690 700
QRPRQMGVAR GEAAEALSLT HRHGDLSKVE ASATLKRRIR AKQSQQEGVK
710 720 730 740 750
FLLTESDTVK RRPKLKDKEQ EPAPLSVYQN GTATIKRRPA SETSSMEAMS
760 770 780 790 800
PAEHQERYDY AAAQPPPEGE PKKVVKPPVS PKPVLPQKVS GPPTPTSKKA
810 820 830 840 850
PIPGPGSPEV KRIHGTPPPI SPKPMPPPTA PKPKVHAVLQ SVSASSTPAP
860 870 880 890 900
SPAKQLGPTA IKPSSTPPSL CSSPAKPLSP GAGSGVPSHT VPVKPPRSSM
910 920 930 940 950
AGPSVESSVA SSTESVHQKL EETSASLAAA LQAVEEKIKQ EDGQAADSAA
960 970
ENKSTVSILD DIGSMFDDLA DQLDAMLE
Length:978
Mass (Da):104,696
Last modified:September 29, 2021 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i228F2CEDA5565AFD
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000010881; ENSACAP00000010660; ENSACAG00000010850

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000010660

Genome annotation databases

EnsembliENSACAT00000010881; ENSACAP00000010660; ENSACAG00000010850

Phylogenomic databases

eggNOGiKOG0507, Eukaryota
GeneTreeiENSGT00940000158025
HOGENOMiCLU_003619_1_0_1
InParanoidiH9GGW2
OMAiHRESPGY
TreeFamiTF320582

Gene expression databases

BgeeiENSACAG00000010850, Expressed in brain and 10 other tissues

Family and domain databases

CDDicd09497, SAM_caskin1_2_repeat1, 1 hit
cd09498, SAM_caskin1_2_repeat2, 1 hit
Gene3Di1.10.150.50, 2 hits
InterProiView protein in InterPro
IPR027013, Caskin-1/2
IPR035497, Caskin1/2_SAM_1
IPR035498, Caskin1/2_SAM_2
IPR032117, Caskin_C
IPR001660, SAM
IPR013761, SAM/pointed_sf
PANTHERiPTHR24174:SF11, PTHR24174:SF11, 1 hit
PfamiView protein in Pfam
PF16632, Caskin-tail, 1 hit
PF00536, SAM_1, 2 hits
SMARTiView protein in SMART
SM00454, SAM, 2 hits
SUPFAMiSSF47769, SSF47769, 2 hits
PROSITEiView protein in PROSITE
PS50105, SAM_DOMAIN, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GGW2_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GGW2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: September 29, 2021
Last modified: September 29, 2021
This is version 52 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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