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UniProtKB - H9GFP6 (H9GFP6_ANOCA)

Entry version 54 (02 Dec 2020)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

AHI1

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AHI1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000009806, Expressed in forelimb bud and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000009650

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini644 – 873WD_REPEATS_REGIONInterPro annotationAdd BLAST230
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati644 – 678WDPROSITE-ProRule annotationAdd BLAST35
Repeati687 – 720WDPROSITE-ProRule annotationAdd BLAST34
Repeati734 – 775WDPROSITE-ProRule annotationAdd BLAST42
Repeati843 – 873WDPROSITE-ProRule annotationAdd BLAST31
Domaini1057 – 1117SH3InterPro annotationAdd BLAST61

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni248 – 322DisorderedSequence analysisAdd BLAST75
Regioni1219 – 1243DisorderedSequence analysisAdd BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili172 – 208Sequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi278 – 294PolyampholyteSequence analysisAdd BLAST17
Compositional biasi1226 – 1243PolarSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation, WD repeatPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0266, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156509

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_007778_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		H9GFP6

Database of Orthologous Groups

More...OrthoDBi		1176970at2759

TreeFam database of animal gene trees

More...TreeFami		TF329226

Family and domain databases

Conserved Domains Database

More...CDDi		cd11812, SH3_AHI-1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR035832, AHI1_SH3
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00018, SH3_1, 1 hit
PF00400, WD40, 3 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00452, SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00326, SH3, 1 hit
SM00320, WD40, 7 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50044, SSF50044, 1 hit
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50002, SH3, 1 hit
PS00678, WD_REPEATS_1, 2 hits
PS50082, WD_REPEATS_2, 4 hits
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GFP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKMPAEESEA KAKTKVRFEE IFRSHVGLTD KKKLKEKRSS IPDNIVLETF 
        60         70         80         90        100
KNHLDPSKEN DEIIVNNIFN PEERRIHKLG SKAPVAVKIN NNVVGGENIK 
       110        120        130        140        150
QTKMNNKKKT TLQKQLNEEA TLSEMKLDGS EKELHVYSKK KTKSILQADA 
       160        170        180        190        200
FHQKGDSNIK GALNGVRDMS ELDEEEQLIQ VYEQQVAEEE ANAIKKKIKK 
       210        220        230        240        250
KLKEQMSEFT SSVQSHEVVL NNEMSKRKKK KKELPVLFAP HSSVMTLSEL 
       260        270        280        290        300
QKYPGEESNS KKSSLERPLI SKSAEDALTE APHWEEDADK LKSKGKKIKI 
       310        320        330        340        350
KSKKALEEDP EQPAESMSHV ASSVSPEPKL VFDDSLVLGV FIHRTDRLKT 
       360        370        380        390        400
DLMVSHPMVK IHVIDQNTGL YVKKENSSRP VSSFYEQEKV GHILPIMTQP 
       410        420        430        440        450
YDFKKFKSTL PEWEEQIIFN ERFNYFLQDA EERPRVILFF EILDFLSIND 
       460        470        480        490        500
VKANFDGQAQ ESGFRKICWA FLKLVGANGV LNVGGKLRLQ LYSPPPRARS 
       510        520        530        540        550
QLNVVEVYDW WAKCPRNHYP STLYVTIKGI KLPEHVDPSL RSMMAVQQEY 
       560        570        580        590        600
NSPSFLELQR EVAKKVNNSG PQIKKEEPFK WSKLPGQVCR IPNKYLFSLR 
       610        620        630        640        650
AGDMGCFCVR FSEDGRTLAA GCAGRDGYPI LLYEIPSGQY LQEFFGHLNI 
       660        670        680        690        700
VYDICWSKDN QHLLTASSDG TARMWKLEIQ ITSAMKVFPH PSFVYAAKYH 
       710        720        730        740        750
PTAEYIIVTG CYDAVIRVWN AEVKEIHGQL LQEFDGHRGF VNTLCFDAEG 
       760        770        780        790        800
FHMFSGDSTG LIIVWNTYVK ESSQSPVQHW GIEKEIKDDD IKGIAVSHLE 
       810        820        830        840        850
VHPNGRRLLI HAKDSTVRIM DLRILATKKY IGATNYRERI CSALTPCGTF 
       860        870        880        890        900
LFSGSEDGKA YVWNAETGDQ VAMYSDLSFT SPLRDVAFHP HEHMVSFCAY 
       910        920        930        940        950
GQNQPILVYI YDYRVAQQDV ELVKDFSGLH LSTSSRGPQI LTGISAQKDT 
       960        970        980        990       1000
INHPSDQFAS VAGVSMRMQK VKQKLDSVTA SFSPLIPSPS LLSPHSKLRL 
      1010       1020       1030       1040       1050
ASTLGEPPQI PLYSLPTQSG SFIPVGNPFS RTSSAGLCMN AEFPAASCGK 
      1060       1070       1080       1090       1100
GDYGSTPVQE TVVALYDYTA HRSDELTIHC RDIIRVLYKD NENWWFGSLA 
      1110       1120       1130       1140       1150
NGQQGYFPAN YVVGETQYEE QPSPGLAGDS TPLLFSELAE GTSPAVPEMS 
      1160       1170       1180       1190       1200
AVISQSGDQR FISENDTDYL TRQGARKKTK KKAIHMEEKE YKANVITHDD 
      1210       1220       1230       1240 
FPSNDVEDEL KKNLMVKRKK RHVKTANGSG TSNDAFQLDS PNT
Length:1,243
Mass (Da):140,236
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1DAB741450341729
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAWZ02013237 Genomic DNA No translation available.
AAWZ02013238 Genomic DNA No translation available.
AAWZ02013239 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		XP_008112735.1, XM_008114528.2
XP_008112736.1, XM_008114529.2
XP_008112737.1, XM_008114530.2
XP_008112739.1, XM_008114532.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000009847; ENSACAP00000009650; ENSACAG00000009806

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100552011

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		acs:100552011

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02013237 Genomic DNA No translation available.
AAWZ02013238 Genomic DNA No translation available.
AAWZ02013239 Genomic DNA No translation available.
RefSeqiXP_008112735.1, XM_008114528.2
XP_008112736.1, XM_008114529.2
XP_008112737.1, XM_008114530.2
XP_008112739.1, XM_008114532.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000009650

Genome annotation databases

EnsembliENSACAT00000009847; ENSACAP00000009650; ENSACAG00000009806
GeneIDi100552011
KEGGiacs:100552011

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54806

Phylogenomic databases

eggNOGiKOG0266, Eukaryota
GeneTreeiENSGT00940000156509
HOGENOMiCLU_007778_0_0_1
InParanoidiH9GFP6
OrthoDBi1176970at2759
TreeFamiTF329226

Gene expression databases

BgeeiENSACAG00000009806, Expressed in forelimb bud and 14 other tissues

Family and domain databases

CDDicd11812, SH3_AHI-1, 1 hit
Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR035832, AHI1_SH3
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00018, SH3_1, 1 hit
PF00400, WD40, 3 hits
PRINTSiPR00452, SH3DOMAIN
SMARTiView protein in SMART
SM00326, SH3, 1 hit
SM00320, WD40, 7 hits
SUPFAMiSSF50044, SSF50044, 1 hit
SSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50002, SH3, 1 hit
PS00678, WD_REPEATS_1, 2 hits
PS50082, WD_REPEATS_2, 4 hits
PS50294, WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GFP6_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GFP6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: June 26, 2013
Last modified: December 2, 2020
This is version 54 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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