Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - H9GEL0 (H9GEL0_ANOCA)

Entry version 41 (12 Aug 2020)
Sequence version 1 (16 May 2012)
Previous versions | rss
Add a publicationFeedback
Protein

VIT domain-containing protein

Gene

VWA5B2

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
VIT domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:VWA5B2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000008895, Expressed in female gonad and 7 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000008764

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 135VITInterPro annotationAdd BLAST135

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni596 – 620DisorderedSequence analysisAdd BLAST25
Regioni644 – 663DisorderedSequence analysisAdd BLAST20
Regioni695 – 755DisorderedSequence analysisAdd BLAST61
Regioni1048 – 1087DisorderedSequence analysisAdd BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi695 – 748PolarSequence analysisAdd BLAST54
Compositional biasi1064 – 1085PolarSequence analysisAdd BLAST22

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QW0V, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157096

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_005270_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		H9GEL0

Identification of Orthologs from Complete Genome Data

More...OMAi		SRCFSFG

TreeFam database of animal gene trees

More...TreeFami		TF329720

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013694, VIT
IPR002035, VWF_A
IPR036465, vWFA_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13757, VIT_2, 1 hit
PF13768, VWA_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00327, VWA, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53300, SSF53300, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51468, VIT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GEL0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGLYCLPAW TALPLQSSCV QACANGYSLG LTVHLTYINL EQQPVDGVFV 
        60         70         80         90        100
YPLEESEVVS SFEAATGSRA STFQIQNRPR MEECCLDCNA SWNQPLRCTN 
       110        120        130        140        150
GHLVLDEDLA HSTFIISTGP IGPSETLTVT LSSSQELATL PNGALRVLFP 
       160        170        180        190        200
SVLMPFIDTI PESESEARGL CDDSSPCVGF TLLKTPSHTH STSCFGSAGL 
       210        220        230        240        250
KSEQSFLVPP KETDVFRGKV YNPFPYEFTF EMLVKGPCLL AGLESPSHAL 
       260        270        280        290        300
RADANPFASS ASTICITLAE QHKCDRNLEI ILYPCEPHYP HLIIEEGAMT 
       310        320        330        340        350
YHEYETHIRN RRDYARIAKK DNDGERQVSF VQKRFHKDIF HNPVLMLNFC 
       360        370        380        390        400
PEMSSVSTDF HTVTREMLFL IDRSGSATKD ALLVAVKSLP SGTLLNVVGF 
       410        420        430        440        450
GSCIKPLFSA SKPCNSETLR MASEYIRKLR TDLGGPNLLA ALTWILGQPL 
       460        470        480        490        500
QRGFPRQLFL LTGSGAGNTG RIIELVRRQA ATVRCFTFGL GSGACHRLLQ 
       510        520        530        540        550
GLAKVSRGRA EFLNPGERLQ PKLIKSLKKA IEPAVSDITI DWYVPDTMEA 
       560        570        580        590        600
LLSPNEIAVL YPGDRLISYC TLYHIASFRD KKPTGREQMC RSLSRGSAGS 
       610        620        630        640        650
VFPSQDEAVG QEEAQAQPVG ESPDICKALH DISREISLEF SAEESMKSEY 
       660        670        680        690        700
THPNPFSMTG GDPVSGGDIW KRIYQPSYIQ EQYVLTHCSV STDQSQGLFS 
       710        720        730        740        750
HSSTSSESTG SRDVPPEGSS LALESNSQQG QKSVSLCNSS TKSAPLPQDK 
       760        770        780        790        800
TGAGTKVSVA ASSEELVRKK ALARAALCGR SFSSPHGELD AHRLRRALEK 
       810        820        830        840        850
VSKKRNRSVE GKLDEIGPEL QKMPKGIADS SNMLSPANLD WDMLLEPPYL 
       860        870        880        890        900
FSPSPAATEP GESEGSSWPP LRCQVVIHAL SAGKPVSWEV TVALDSLLLA 
       910        920        930        940        950
KDSQEPSQQQ EQSKAWDKLL HRLTAGSVIR DNENVAQREA ELEHVTHHTS 
       960        970        980        990       1000
HTRFFAMQSS KACNTPSIYT SIVPVDSSTQ ETLPSALEVR STVEIREETT 
      1010       1020       1030       1040       1050
EPPNGGSSIL FLPRAYIATS KGPGQPAGIT AVVPSVWERV RNIQAKRNGN 
      1060       1070       1080       1090       1100
PPAVLHQFPR KIPPSPISVS STAQEKQNCP PDESELSPCN SAIHDYLPLM 
      1110       1120       1130       1140       1150
KLQQAAGMFQ LTESFAEVVQ IPLDRLRRAS PYASHRASLS PASSTSPWAL 
      1160       1170       1180       1190       1200
IAKSTPKPSE NQSTCSEVPS AAVWAQADSG RGSETDACDH SPDVSEADLE 
      1210       1220       1230       1240       1250
SMSWATAVAL AWLEHRSAGF FVEWELLAAK ADAWLRLQQL PDGVDVAALK 
      1260       1270 
GAARQLFLLL RHWDENIKLN MLCYNPNNM
Length:1,279
Mass (Da):139,834
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i78123DE49F0362AB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAWZ02021639 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000008952; ENSACAP00000008764; ENSACAG00000008895

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02021639 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000008764

Genome annotation databases

EnsembliENSACAT00000008952; ENSACAP00000008764; ENSACAG00000008895

Phylogenomic databases

eggNOGiENOG502QW0V, Eukaryota
GeneTreeiENSGT00940000157096
HOGENOMiCLU_005270_1_0_1
InParanoidiH9GEL0
OMAiSRCFSFG
TreeFamiTF329720

Gene expression databases

BgeeiENSACAG00000008895, Expressed in female gonad and 7 other tissues

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR013694, VIT
IPR002035, VWF_A
IPR036465, vWFA_dom_sf
PfamiView protein in Pfam
PF13757, VIT_2, 1 hit
PF13768, VWA_3, 1 hit
SMARTiView protein in SMART
SM00327, VWA, 1 hit
SUPFAMiSSF53300, SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS51468, VIT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GEL0_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GEL0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: August 12, 2020
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again