UniProtKB - H9GD98 (H9GD98_ANOCA)
Protein
Activated RNA polymerase II transcriptional coactivator p15
Gene
SUB1
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- activating transcription factor binding Source: Ensembl
- DNA helicase activity Source: Ensembl
- identical protein binding Source: Ensembl
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: Ensembl
- single-stranded DNA binding Source: Ensembl
- transcription coactivator activity Source: GO_Central
GO - Biological processi
- negative regulation of DNA metabolic process Source: Ensembl
- positive regulation of transcription initiation from RNA polymerase II promoter Source: GO_Central
- protein homooligomerization Source: Ensembl
- SMAD protein signal transduction Source: Ensembl
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Activated RNA polymerase II transcriptional coactivator p15ARBA annotationAlternative name(s): SUB1 homologARBA annotation |
Gene namesi | Name:SUB1Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleolus Source: Ensembl
- nucleoplasm Source: Ensembl
- nucleus Source: GO_Central
Other locations
- transcription regulator complex Source: GO_Central
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSACAG00000007974, Expressed in embryo and 15 other tissues |
Interactioni
GO - Molecular functioni
- activating transcription factor binding Source: Ensembl
- identical protein binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000007795 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 70 – 121 | PC4InterPro annotationAdd BLAST | 52 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 70 | DisorderedSequence analysisAdd BLAST | 70 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 17 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 18 – 49 | PolyampholyteSequence analysisAdd BLAST | 32 | |
Compositional biasi | 51 – 69 | PolarSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Belongs to the transcriptional coactivator PC4 family.ARBA annotation
Phylogenomic databases
eggNOGi | KOG2712, Eukaryota |
GeneTreei | ENSGT00390000008802 |
HOGENOMi | CLU_104273_1_1_1 |
InParanoidi | H9GD98 |
OrthoDBi | 1616655at2759 |
TreeFami | TF313859 |
Family and domain databases
Gene3Di | 2.30.31.10, 1 hit |
InterProi | View protein in InterPro IPR003173, PC4 IPR009044, ssDNA-bd_transcriptional_reg |
Pfami | View protein in Pfam PF02229, PC4, 1 hit |
SUPFAMi | SSF54447, SSF54447, 1 hit |
i Sequence
Sequence statusi: Complete.
H9GD98-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPKSKELVSS SSSGSDSDRE IDTGHVNHLV SDKRKKPVPQ EKPVKKQKTG
60 70 80 90 100
ESSKGAASSK QSSNKDENMF QIGKMRYVSV RDFKGKVLID IREYWMDQEG
110 120 130
EMKPGRKGIS LNPEQWSQLK EQITDIDEAV RKL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02025312 Genomic DNA No translation available. AAWZ02025313 Genomic DNA No translation available. |
RefSeqi | XP_003226001.1, XM_003225953.3 |
Genome annotation databases
Ensembli | ENSACAT00000007961; ENSACAP00000007795; ENSACAG00000007974 |
GeneIDi | 100563239 |
KEGGi | acs:100563239 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02025312 Genomic DNA No translation available. AAWZ02025313 Genomic DNA No translation available. |
RefSeqi | XP_003226001.1, XM_003225953.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000007795 |
Genome annotation databases
Ensembli | ENSACAT00000007961; ENSACAP00000007795; ENSACAG00000007974 |
GeneIDi | 100563239 |
KEGGi | acs:100563239 |
Organism-specific databases
CTDi | 10923 |
Phylogenomic databases
eggNOGi | KOG2712, Eukaryota |
GeneTreei | ENSGT00390000008802 |
HOGENOMi | CLU_104273_1_1_1 |
InParanoidi | H9GD98 |
OrthoDBi | 1616655at2759 |
TreeFami | TF313859 |
Gene expression databases
Bgeei | ENSACAG00000007974, Expressed in embryo and 15 other tissues |
Family and domain databases
Gene3Di | 2.30.31.10, 1 hit |
InterProi | View protein in InterPro IPR003173, PC4 IPR009044, ssDNA-bd_transcriptional_reg |
Pfami | View protein in Pfam PF02229, PC4, 1 hit |
SUPFAMi | SSF54447, SSF54447, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GD98_ANOCA | |
Accessioni | H9GD98Primary (citable) accession number: H9GD98 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | June 26, 2013 | |
Last modified: | August 12, 2020 | |
This is version 48 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |