UniProtKB - H9GCM4 (H9GCM4_ANOCA)
Protein
Submitted name:
Syntaxin 4
Gene
STX4
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- SNAP receptor activity Source: GO_Central
- SNARE binding Source: GO_Central
- sphingomyelin phosphodiesterase activator activity Source: Ensembl
GO - Biological processi
- cellular response to interferon-gamma Source: Ensembl
- cellular response to oxidative stress Source: Ensembl
- cornified envelope assembly Source: Ensembl
- exocytosis Source: GO_Central
- intracellular protein transport Source: GO_Central
- long-term synaptic potentiation Source: Ensembl
- positive regulation of cell adhesion Source: Ensembl
- positive regulation of cell migration Source: Ensembl
- positive regulation of cell population proliferation Source: Ensembl
- positive regulation of chemotaxis Source: Ensembl
- positive regulation of eosinophil degranulation Source: Ensembl
- positive regulation of immunoglobulin secretion Source: Ensembl
- positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: Ensembl
- positive regulation of protein localization to cell surface Source: Ensembl
- positive regulation of protein localization to plasma membrane Source: Ensembl
- regulation of extrinsic apoptotic signaling pathway via death domain receptors Source: Ensembl
- SNARE complex assembly Source: Ensembl
- synaptic vesicle fusion to presynaptic active zone membrane Source: GO_Central
- vesicle docking Source: GO_Central
- vesicle fusion Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Syntaxin 4Imported |
Gene namesi | Name:STX4Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Endosome
- endosome Source: Ensembl
Extracellular region or secreted
- extracellular space Source: Ensembl
Golgi apparatus
- trans-Golgi network Source: Ensembl
Plasma Membrane
- basolateral plasma membrane Source: Ensembl
- plasma membrane Source: GO_Central
- presynaptic active zone membrane Source: GO_Central
- presynaptic membrane Source: GO_Central
Other locations
- cell surface Source: Ensembl
- dendritic spine Source: Ensembl
- endomembrane system Source: GO_Central
- glutamatergic synapse Source: Ensembl
- integral component of membrane Source: GO_Central
- lamellipodium Source: Ensembl
- lateral loop Source: Ensembl
- myelin sheath adaxonal region Source: Ensembl
- perinuclear region of cytoplasm Source: Ensembl
- phagocytic vesicle Source: Ensembl
- SNARE complex Source: GO_Central
- specific granule Source: Ensembl
- storage vacuole Source: Ensembl
- synaptic vesicle Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 276 – 299 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSACAG00000007287, Expressed in dewlap and 14 other tissues |
Interactioni
GO - Molecular functioni
- SNARE binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000007253 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 202 – 264 | T-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 63 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 40 | DisorderedSequence analysisAdd BLAST | 40 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 47 – 74 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 78 – 105 | Sequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 18 | PolyampholyteSequence analysisAdd BLAST | 18 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilPROSITE-ProRule annotationARBA annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG0810, Eukaryota |
GeneTreei | ENSGT01010000222341 |
HOGENOMi | CLU_042423_2_2_1 |
InParanoidi | H9GCM4 |
OMAi | EADENCN |
TreeFami | TF313763 |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
H9GCM4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRDRTHELRE KGDDSDSENA ELEALVTRGS GKSNDLLDPT DEFFQTTRGI
60 70 80 90 100
REALRTLENK VKELEKKQTT ILATPLPEDS MKQSLQTLRD EIKELSKDIR
110 120 130 140 150
TRLKKIEPKK DEEDENRNSV NTRMKRTQHG ILSQQFLDLI NKCNSIQSEY
160 170 180 190 200
RDRNLERIKR QLQITDNRVV SDEELDQMLE SGQTEVFVSN IMKDTQVTKQ
210 220 230 240 250
ALNEIETRHS EILKLERSIQ ELHEMFMYLA TEVELQGEMI DRIEKNILDS
260 270 280 290 300
GDYVKKGQVH LQKAQENQKK ARRKKFMIAI CLTITLAIII TIVGVLIAVG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02020210 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSACAT00000007408; ENSACAP00000007253; ENSACAG00000007287 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02020210 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000007253 |
Genome annotation databases
Ensembli | ENSACAT00000007408; ENSACAP00000007253; ENSACAG00000007287 |
Phylogenomic databases
eggNOGi | KOG0810, Eukaryota |
GeneTreei | ENSGT01010000222341 |
HOGENOMi | CLU_042423_2_2_1 |
InParanoidi | H9GCM4 |
OMAi | EADENCN |
TreeFami | TF313763 |
Gene expression databases
Bgeei | ENSACAG00000007287, Expressed in dewlap and 14 other tissues |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GCM4_ANOCA | |
Accessioni | H9GCM4Primary (citable) accession number: H9GCM4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | May 16, 2012 | |
Last modified: | December 2, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |