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Entry version 54 (29 Sep 2021)
Sequence version 3 (29 Sep 2021)
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Protein
Submitted name:

Calmodulin regulated spectrin associated protein family member 2

Gene

CAMSAP2

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Calmodulin regulated spectrin associated protein family member 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CAMSAP2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation, MicrotubulePROSITE-ProRule annotationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000006193, Expressed in testis and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000006068

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The CKK domain binds microtubules.PROSITE-ProRule annotation

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CAMSAP1 family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3654, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182975

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004833_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H9GB30

Identification of Orthologs from Complete Genome Data

More...
OMAi
RGLYTWD

Database of Orthologous Groups

More...
OrthoDBi
741937at2759

TreeFam database of animal gene trees

More...
TreeFami
TF315529

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.20.360, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032940, CAMSAP
IPR031372, CAMSAP_CC1
IPR022613, CAMSAP_CH
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR038209, CKK_dom_sf
IPR014797, CKK_domain
IPR011033, PRC_barrel-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR21595, PTHR21595, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17095, CAMSAP_CC1, 1 hit
PF11971, CAMSAP_CH, 1 hit
PF08683, CAMSAP_CKK, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01051, CAMSAP_CKK, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit
SSF50346, SSF50346, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021, CH, 1 hit
PS51508, CKK, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GB30-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDAVEAKEL RKTFIVPAIK PFDHYDFPRA KIACNLAWLV AKAFGTENVP
60 70 80 90 100
EELREPFYTD QYDQEHIKPP VVHLLLSAEL YCRAGSLILK SDAAKPLLGH
110 120 130 140 150
DAVIQALAQK GLYVTDQEKL VTERDLHKKP IQMSAHLAMI DTLMMAYTVE
160 170 180 190 200
MISVEKVIAC VQQYSSFFQA TDLPYDIEDA VMFWINKVNE HLKDIMEQEQ
210 220 230 240 250
KLKEHLSVET PGGQKARYRK EQALLKQLPC IPLVENLLKD GTDGCALAAL
260 270 280 290 300
IHFYCPDVIR LEDICLKETM SLADSLYNLQ LIQEFCQEYL NRCCHFSLED
310 320 330 340 350
MLYAASSIKN NYLVFMAELF WWFEVVKPSF VQPRVVVHPQ AEPTKQASSL
360 370 380 390 400
SDANANRRHY PDVSRDSELT ASMEGPSHQI LPSHGHQQPY SSAAGSIRRS
410 420 430 440 450
SSMSYMDGYV GTWPKEKRSS VHGVSFDISF DKEDSMHIRT PKRGITRSLS
460 470 480 490 500
NEGLEQNANR MPRHIRKNIS FKPVNGEEES DDIEEEKDVE FYSHLEDNSN
510 520 530 540 550
QRNANQINPY CLPNGALQNR LVTDEFGNQI ETPSIEQALQ IIHDNEKSSG
560 570 580 590 600
VTQPEQITNG FFLHNAEMSI LNSNLKSNQT SPDIIADTKG ALSPVTDNTE
610 620 630 640 650
VDTGIHVPSD IPETMDEDST LRDYTVSLDS DMEESSRFLH EYDGRGSNHK
660 670 680 690 700
ELLSPCPSSV SAKSQAGSSA SSSSGIKMTS FAEQKFKKLN HTDSRSSGSS
710 720 730 740 750
SQKTTPEGSE LNIPHMVSWA QIPEESPVPQ SRDTTQLLAS EMVQLKMKLE
760 770 780 790 800
EKRRAIEAQK KKVEAAFTKQ RQKMGRTAFL SIVKKKSDTI SPFREEAAGA
810 820 830 840 850
EDEKVFTDST KLKEKETPKP GEHLNKMAEM IKTSSEKPHV KWLKSPNTTV
860 870 880 890 900
DTEKQCHLVS PSKDNLNEGD FLEYTKSIEK LNSSLNFLQQ EMQRLSLQQE
910 920 930 940 950
MLMQMREQQA WVISPPQPSP QKQIRELKPS LKFTGSSAPI APFSVESPRP
960 970 980 990 1000
SHQSPQASSR KNSTLPVKMQ RTPRPNELKL TPLNRTLTAP RSVDSLPRLR
1010 1020 1030 1040 1050
RFSPSQASIQ TRSFVYFGDD GERNLSKEVK STTEEAPGKE DTAKGEGGEK
1060 1070 1080 1090 1100
ATEELDEQKP EQQQLLKPLE STVSEVLSQP ITEIVRLTPS EELLDPSSLL
1110 1120 1130 1140 1150
VPPPKTVNLI EVSLTDLKPP EKSEEIVEKS EGESDKEQLE DDQKLCCGFF
1160 1170 1180 1190 1200
FKDDQKPEND MAVKRAALLE KRLRRERETL LRKQQLEAEL ETKKEETKRK
1210 1220 1230 1240 1250
SEEERQKKED EKARREFIKQ EYMRRKQLKL MEDMDIIIKP RSHSAKQKKP
1260 1270 1280 1290 1300
RPKSIHRDHI ESPKTPIKGP PGSQPDCVVD VVSPPSPVSS LSLASLNTGD
1310 1320 1330 1340 1350
NESIQSGKRT PRSESVEGFI SPSRCGSRNG EKDWENASTT SSVASATEYT
1360 1370 1380 1390 1400
GPKLYKEPSA KSNKHIIQNA LAHCCLAGKV NEGQKNKILE EMEKSDANNF
1410 1420 1430 1440 1450
LILFRDSGCQ FRSLYTYCPE TEEISKLTGI GPKSISKKMI EGLYKYNSDR
1460 1470 1480 1490
KQFSHIPAKT LSASVDAITI HSHLWQSKRP VTPKKLLPAK A
Length:1,491
Mass (Da):168,132
Last modified:September 29, 2021 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0157B7BD9485568
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_008113234.1, XM_008115027.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000006203; ENSACAP00000006068; ENSACAG00000006193

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100564859

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_008113234.1, XM_008115027.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000006068

Genome annotation databases

EnsembliENSACAT00000006203; ENSACAP00000006068; ENSACAG00000006193
GeneIDi100564859

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23271

Phylogenomic databases

eggNOGiKOG3654, Eukaryota
GeneTreeiENSGT00950000182975
HOGENOMiCLU_004833_1_0_1
InParanoidiH9GB30
OMAiRGLYTWD
OrthoDBi741937at2759
TreeFamiTF315529

Gene expression databases

BgeeiENSACAG00000006193, Expressed in testis and 14 other tissues

Family and domain databases

Gene3Di3.10.20.360, 1 hit
InterProiView protein in InterPro
IPR032940, CAMSAP
IPR031372, CAMSAP_CC1
IPR022613, CAMSAP_CH
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR038209, CKK_dom_sf
IPR014797, CKK_domain
IPR011033, PRC_barrel-like_sf
PANTHERiPTHR21595, PTHR21595, 1 hit
PfamiView protein in Pfam
PF17095, CAMSAP_CC1, 1 hit
PF11971, CAMSAP_CH, 1 hit
PF08683, CAMSAP_CKK, 1 hit
SMARTiView protein in SMART
SM01051, CAMSAP_CKK, 1 hit
SUPFAMiSSF47576, SSF47576, 1 hit
SSF50346, SSF50346, 1 hit
PROSITEiView protein in PROSITE
PS50021, CH, 1 hit
PS51508, CKK, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GB30_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GB30
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: September 29, 2021
Last modified: September 29, 2021
This is version 54 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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