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Entry version 37 (12 Aug 2020)
Sequence version 2 (26 Jun 2013)
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Protein

Ribosomal_L7Ae domain-containing protein

Gene

SECISBP2L

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ribosomal_L7Ae domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SECISBP2LImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000006021, Expressed in female gonad and 15 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000005967

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini673 – 773Ribosomal_L7AeInterPro annotationAdd BLAST101

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni134 – 175DisorderedSequence analysisAdd BLAST42
Regioni201 – 259DisorderedSequence analysisAdd BLAST59
Regioni283 – 396DisorderedSequence analysisAdd BLAST114
Regioni500 – 535DisorderedSequence analysisAdd BLAST36
Regioni584 – 609DisorderedSequence analysisAdd BLAST26
Regioni855 – 875DisorderedSequence analysisAdd BLAST21
Regioni903 – 1064DisorderedSequence analysisAdd BLAST162

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili770 – 805Sequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi134 – 156PolarSequence analysisAdd BLAST23
Compositional biasi245 – 259PolarSequence analysisAdd BLAST15
Compositional biasi305 – 322PolarSequence analysisAdd BLAST18
Compositional biasi337 – 353PolarSequence analysisAdd BLAST17
Compositional biasi917 – 951PolarSequence analysisAdd BLAST35
Compositional biasi953 – 971AcidicSequence analysisAdd BLAST19
Compositional biasi974 – 1000PolarSequence analysisAdd BLAST27
Compositional biasi1009 – 1027AcidicSequence analysisAdd BLAST19
Compositional biasi1041 – 1064PolarSequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QUP4, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00490000043356

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_009625_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H9GAY6

TreeFam database of animal gene trees

More...
TreeFami
TF328821

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1330.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029064, L30e-like
IPR004038, Ribosomal_L7Ae/L30e/S12e/Gad45
IPR040051, SECISBP2

The PANTHER Classification System

More...
PANTHERi
PTHR13284, PTHR13284, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01248, Ribosomal_L7Ae, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55315, SSF55315, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9GAY6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMPMALPNEN GGVNGVEAAP IPSYLITCYP FVQENQSNRQ LPLYNNDIRW
60 70 80 90 100
QQPNPNPAGP YLAYPILSAQ PPVSTEYTYY QLMPAPCAQV MGFYHPFPAP
110 120 130 140 150
YSAPFQTASA MNTVTTECTD RPTQPNQVFP MCSQRSRSAS RGSIVQKQQQ
160 170 180 190 200
PLQTHIKSKR PPVKSVATQK ETCASGPETR PKIVLLVDAC QQTDFPSEIA
210 220 230 240 250
SKSLSESMST MHWKPKTRRR RSSHPAESSS EQGASEADID SDSGYCSPKH
260 270 280 290 300
SNQAAAVTSR SVESAAGNIL EPSVHPAGAT WANVSSQATQ KKPWMERTPA
310 320 330 340 350
FSRGGRQAEQ HNSSQPAFRC RGHSTSSERR QNLQKKPEKP VSSSQSSKRE
360 370 380 390 400
QSPGSLYFED EEEFPELNSD SGNSKGGNMQ LKNAPKVLDD LPENSPINIV
410 420 430 440 450
QTPIPITTSV PKRAKSQKKK ALAAALATAQ EYSEISMEQR KLQEAVSKAA
460 470 480 490 500
GKKSKTPVQL DLGDMLAALE KQQQAMKARQ ITNTRPLSYT VGNAAPFHTK
510 520 530 540 550
ESTNRKSLAK GQPSVGCLNP LDSTSPKVKR GKERELSKLK RPTALKKIIL
560 570 580 590 600
KEREEKKGRL SVDHTIVGAD EEQEVDLNLT PNQSEELASQ EEPGLSVPSD
610 620 630 640 650
TSLSPASQNS PYCMTPVSQG SPASSGIGSP MASSTITKIH SKRFREYCNQ
660 670 680 690 700
VLSKEIDECV TLLLQELVSF QEQIYQKDPM RAKAKRRLVM GLREVTKHMK
710 720 730 740 750
LSKIKCVIIS PNCEKIQSKG GLDEALYNVI AMAREQEIPF VFALGRKALG
760 770 780 790 800
RCVNKLVPVS VVGIFNYSGA ENLFNKLVSL TEEARKAYRD MVAAMEQEQE
810 820 830 840 850
EALKNVKKVP HHMGHSRNPS AASAISFCSV ISEPISEVNE KEYETNWRSM
860 870 880 890 900
VETSDGLEAS ENEREASFKS AVPEKPGNSN KVIVNKELSL AAVGVVTVSA
910 920 930 940 950
QVKAPSGKEE VKPDDNLEWA SQQSTDTGSL DGSCRDILNS SMTSTTSTLV
960 970 980 990 1000
PGMLEEEDDE EDEDEDDYTH EPISEEVQLN SRIESWVSET QRTMETLQLG
1010 1020 1030 1040 1050
KSLSGGEDDN AEQSEDEELE TPEQVESVVE SEEWTAEKHS NKAQQKPAVS
1060
TSLDTTPMDS NYIP
Length:1,064
Mass (Da):116,989
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i802AE5C1FB3AFAE0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAWZ02029372 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000006101; ENSACAP00000005967; ENSACAG00000006021

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02029372 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000005967

Genome annotation databases

EnsembliENSACAT00000006101; ENSACAP00000005967; ENSACAG00000006021

Phylogenomic databases

eggNOGiENOG502QUP4, Eukaryota
GeneTreeiENSGT00490000043356
HOGENOMiCLU_009625_0_0_1
InParanoidiH9GAY6
TreeFamiTF328821

Gene expression databases

BgeeiENSACAG00000006021, Expressed in female gonad and 15 other tissues

Family and domain databases

Gene3Di3.30.1330.30, 1 hit
InterProiView protein in InterPro
IPR029064, L30e-like
IPR004038, Ribosomal_L7Ae/L30e/S12e/Gad45
IPR040051, SECISBP2
PANTHERiPTHR13284, PTHR13284, 1 hit
PfamiView protein in Pfam
PF01248, Ribosomal_L7Ae, 1 hit
SUPFAMiSSF55315, SSF55315, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9GAY6_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9GAY6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: June 26, 2013
Last modified: August 12, 2020
This is version 37 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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