UniProtKB - H9GA02 (H9GA02_ANOCA)
Protein
Alpha-1,4 glucan phosphorylase
Gene
PYGM
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.UniRule annotation
Catalytic activityi
- [(1→4)-α-D-glucosyl](n) + phosphate = [(1→4)-α-D-glucosyl](n-1) + α-D-glucose 1-phosphateUniRule annotationARBA annotationEC:2.4.1.1UniRule annotationARBA annotation
Cofactori
pyridoxal 5'-phosphateUniRule annotationARBA annotation
GO - Molecular functioni
- glycogen phosphorylase activity Source: GO_Central
- linear malto-oligosaccharide phosphorylase activity Source: UniProtKB-EC
- pyridoxal phosphate binding Source: GO_Central
- SHG alpha-glucan phosphorylase activity Source: UniProtKB-EC
GO - Biological processi
- glycogen catabolic process Source: GO_Central
Keywordsi
Molecular function | Allosteric enzymeARBA annotation, GlycosyltransferaseUniRule annotationARBA annotation, Transferase |
Biological process | Carbohydrate metabolism, Glycogen metabolismARBA annotation |
Ligand | Pyridoxal phosphateUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:PYGMImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Other locations
- cytoplasm Source: GO_Central
PTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 604 | N6-(pyridoxal phosphate)lysineUniRule annotation | 1 |
Expressioni
Gene expression databases
Bgeei | ENSACAG00000005131, Expressed in skeletal muscle tissue and 11 other tissues |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG2099, Eukaryota |
GeneTreei | ENSGT00950000183148 |
HOGENOMi | CLU_010198_1_1_1 |
InParanoidi | H9GA02 |
OMAi | KSPIDFN |
TreeFami | TF300309 |
Family and domain databases
InterProi | View protein in InterPro IPR011833, Glycg_phsphrylas IPR000811, Glyco_trans_35 IPR035090, Pyridoxal_P_attach_site |
PANTHERi | PTHR11468, PTHR11468, 1 hit |
Pfami | View protein in Pfam PF00343, Phosphorylase, 1 hit |
PIRSFi | PIRSF000460, Pprylas_GlgP, 1 hit |
TIGRFAMsi | TIGR02093, P_ylase, 1 hit |
PROSITEi | View protein in PROSITE PS00102, PHOSPHORYLASE, 1 hit |
i Sequence
Sequence statusi: Complete.
H9GA02-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQRIYYLSLE FYMGRTLQNT MVNLALQNAC DEATYQLGLD MEELQEIEED
60 70 80 90 100
AGLGNGGLGR LAACFLDSMA TLGLAAYGYG IRYEFGIFNQ KICGGWQLEE
110 120 130 140 150
ADDWLRYGNP WEKARPEYMI PVHFYGRIQH DHDGVKWVDT QVVLALPYDT
160 170 180 190 200
PVPGYRNNTV NTMRLWSARA PNEFNLKDFN VGGYIQAVLD RNLAENISRV
210 220 230 240 250
LYPNDNFFEG KELRLKQEYF VVAATLQDII RRFKSSKFGS RDPVRTSFDA
260 270 280 290 300
FPDKVAIQLN DTHPSLTIPE LMRVLVDIEK LDWDKKTTTT ITKRTITFVS
310 320 330 340 350
HPSHPKGDSE WLTNYIQQIC PKSLVNGWLS LSLSAQKVYA KFPGDLDRMR
360 370 380 390 400
RMSMVEEGSV KRINMAHLCI VGSHAVNGVA RIHSEILKAT VFKDFYEFEP
410 420 430 440 450
HKFQNKTNGI TPRRWLVLCN PGLAEIIAER IGEDYISDLD QLKKLLAFVE
460 470 480 490 500
DEGFIRDIAK VKQENKLKFS AYLEKEYKVK INPNSLFDIQ VKRIHEYKRQ
510 520 530 540 550
LLNCLHIITF YNRIKKEPNK HFVPRTIMIG GKAAPGYHMA KMIIKLITSI
560 570 580 590 600
GDIVNNDPVI GDRLKVIFLE NYRVSLAEKV VPAADLSEQI STAGTEASGT
610 620 630 640 650
GNMKFMLNGA LTIGTMDGAN VEMAEEAGEE NFFIFGMRVE DVDELDRKGY
660 670 680 690 700
CAKDYYDHIP ELKQAIDQMS SGFFSPKQPD LFKDIVNMLM YHDRFKVFAD
710 720 730 740 750
YEAYIKCQEK VSALYKNTKE WTKKVIKNIA TSGKFSSDRT IAQYAREIWG
760
VEPTRQKIPA PDDPRE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02035969 Genomic DNA No translation available. AAWZ02035970 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSACAT00000005240; ENSACAP00000005124; ENSACAG00000005131 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02035969 Genomic DNA No translation available. AAWZ02035970 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000005124 |
Genome annotation databases
Ensembli | ENSACAT00000005240; ENSACAP00000005124; ENSACAG00000005131 |
Phylogenomic databases
eggNOGi | KOG2099, Eukaryota |
GeneTreei | ENSGT00950000183148 |
HOGENOMi | CLU_010198_1_1_1 |
InParanoidi | H9GA02 |
OMAi | KSPIDFN |
TreeFami | TF300309 |
Gene expression databases
Bgeei | ENSACAG00000005131, Expressed in skeletal muscle tissue and 11 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR011833, Glycg_phsphrylas IPR000811, Glyco_trans_35 IPR035090, Pyridoxal_P_attach_site |
PANTHERi | PTHR11468, PTHR11468, 1 hit |
Pfami | View protein in Pfam PF00343, Phosphorylase, 1 hit |
PIRSFi | PIRSF000460, Pprylas_GlgP, 1 hit |
TIGRFAMsi | TIGR02093, P_ylase, 1 hit |
PROSITEi | View protein in PROSITE PS00102, PHOSPHORYLASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9GA02_ANOCA | |
Accessioni | H9GA02Primary (citable) accession number: H9GA02 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | May 16, 2012 | |
Last modified: | August 12, 2020 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |