UniProtKB - H9G8P3 (H9G8P3_ANOCA)
Protein
NADH-cytochrome b5 reductase
Gene
CYB5R2
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Catalytic activityi
- 2 [Fe(III)-cytochrome b5] + NADH = 2 [Fe(II)-cytochrome b5] + H+ + NAD+UniRule annotationARBA annotationEC:1.6.2.2UniRule annotationARBA annotation
Cofactori
FADUniRule annotationARBA annotation
GO - Molecular functioni
- cytochrome-b5 reductase activity, acting on NAD(P)H Source: UniProtKB-EC
- FAD binding Source: GO_Central
Keywordsi
Molecular function | OxidoreductaseUniRule annotation |
Ligand | FADUniRule annotationARBA annotation, Flavoprotein, NADUniRule annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:CYB5R2Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Other locations
- membrane Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000004175, Expressed in kidney and 14 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 128 | FAD-binding FR-typeInterPro annotationAdd BLAST | 113 |
Sequence similaritiesi
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.UniRule annotationARBA annotation
Phylogenomic databases
eggNOGi | KOG0534, Eukaryota |
GeneTreei | ENSGT00940000153962 |
HOGENOMi | CLU_003827_9_2_1 |
InParanoidi | H9G8P3 |
TreeFami | TF314333 |
Family and domain databases
Gene3Di | 3.40.50.80, 1 hit |
InterProi | View protein in InterPro IPR001834, CBR-like IPR008333, Cbr1-like_FAD-bd_dom IPR017927, FAD-bd_FR_type IPR001709, Flavoprot_Pyr_Nucl_cyt_Rdtase IPR039261, FNR_nucleotide-bd IPR001433, OxRdtase_FAD/NAD-bd IPR017938, Riboflavin_synthase-like_b-brl |
Pfami | View protein in Pfam PF00970, FAD_binding_6, 1 hit PF00175, NAD_binding_1, 1 hit |
PRINTSi | PR00406, CYTB5RDTASE PR00371, FPNCR |
SUPFAMi | SSF52343, SSF52343, 1 hit SSF63380, SSF63380, 1 hit |
PROSITEi | View protein in PROSITE PS51384, FAD_FR, 1 hit |
i Sequence
Sequence statusi: Complete.
H9G8P3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGPKTKKALV TLQDPNIKYP LPLIEREEIS HDTRRFRFGL PSSEHILGLP
60 70 80 90 100
VGQHVYISSK VAGNLVIRAY TPVSSDEVKG YVDLIIKVYY KNVHPKFPEG
110 120 130 140 150
GKMSQHLDSM KVGDTIDFRG PNGLLVYKGS GKFSIKQDKK SQAKIKWVKH
160 170 180 190 200
LGMIAGGTGI TPMLQLIRHI TKDPSDKTKC SLLFANQTEQ DILLRPELED
210 220 230 240 250
VAANHPEQFK LWYTLDRPPQ GWKYSSGFVT ADMIKEHLPP PGDDTLILMC
260 270
GPPPMIQFAC QPNLEKLGYA KESTFAY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02021264 Genomic DNA No translation available. AAWZ02021265 Genomic DNA No translation available. AAWZ02021266 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSACAT00000004233; ENSACAP00000004134; ENSACAG00000004175 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02021264 Genomic DNA No translation available. AAWZ02021265 Genomic DNA No translation available. AAWZ02021266 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000004134 |
Genome annotation databases
Ensembli | ENSACAT00000004233; ENSACAP00000004134; ENSACAG00000004175 |
Phylogenomic databases
eggNOGi | KOG0534, Eukaryota |
GeneTreei | ENSGT00940000153962 |
HOGENOMi | CLU_003827_9_2_1 |
InParanoidi | H9G8P3 |
TreeFami | TF314333 |
Gene expression databases
Bgeei | ENSACAG00000004175, Expressed in kidney and 14 other tissues |
Family and domain databases
Gene3Di | 3.40.50.80, 1 hit |
InterProi | View protein in InterPro IPR001834, CBR-like IPR008333, Cbr1-like_FAD-bd_dom IPR017927, FAD-bd_FR_type IPR001709, Flavoprot_Pyr_Nucl_cyt_Rdtase IPR039261, FNR_nucleotide-bd IPR001433, OxRdtase_FAD/NAD-bd IPR017938, Riboflavin_synthase-like_b-brl |
Pfami | View protein in Pfam PF00970, FAD_binding_6, 1 hit PF00175, NAD_binding_1, 1 hit |
PRINTSi | PR00406, CYTB5RDTASE PR00371, FPNCR |
SUPFAMi | SSF52343, SSF52343, 1 hit SSF63380, SSF63380, 1 hit |
PROSITEi | View protein in PROSITE PS51384, FAD_FR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9G8P3_ANOCA | |
Accessioni | H9G8P3Primary (citable) accession number: H9G8P3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | June 26, 2013 | |
Last modified: | August 12, 2020 | |
This is version 47 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |