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Entry version 45 (07 Oct 2020)
Sequence version 1 (16 May 2012)
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Protein
Submitted name:

Nebulin

Gene

NEB

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: GO_Central

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
NebulinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NEBImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000003769, Expressed in skeletal muscle tissue and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000003825

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6757 – 6816SH3InterPro annotationAdd BLAST60

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni6674 – 6704DisorderedSequence analysisAdd BLAST31
Regioni6736 – 6756DisorderedSequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi6674 – 6694PolarSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1702, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154533

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000024_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H9G895

Identification of Orthologs from Complete Genome Data

More...
OMAi
HSPVDMM

Family and domain databases

Conserved Domains Database

More...
CDDi
cd11933, SH3_Nebulin_C, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013998, Nebulin-like
IPR000900, Nebulin_repeat
IPR035629, Nebulin_SH3
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00880, Nebulin, 71 hits
PF14604, SH3_9, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00510, NEBULIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00227, NEBU, 184 hits
SM00326, SH3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50044, SSF50044, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51216, NEBULIN, 187 hits
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9G895-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
KYKEKFEKEK GKPYAITSDT PELRRIKKVQ DQLSEVKYRM AGDQAKTNCH
60 70 80 90 100
VDEKAKDIEH AKKVSQQVSK VLYKQNWEEN KEKYLLPPDA PEFVQAIKNA
110 120 130 140 150
ELYSKKRYIE DWESDKSLFY PYDDSPEMKR VAQAQKALSD IVYKKGHDER
160 170 180 190 200
KAKYTSLPDP PDVELARKVT RQLSDRNYHE DYNKKKGKWS QTPCYDVAVA
210 220 230 240 250
KMNADNLSTR KYQEDWENSK DQIYFMQTET PEYEVNKRAG VVASKVKYKE
260 270 280 290 300
DYEKAKASTD YNVLPATENP MLKHLKHVGN LTNDRLYKEA YEKAKGTSIN
310 320 330 340 350
YCDTPKYQLD NVLKNFSDIK YKEGYQNKIL GRYIGSFEDP YQTHCMKIEA
360 370 380 390 400
MKSDKNYKAD YEDDKGKCYF PQTITQEYEA IKKLDQCKDR GTKKHPDKIK
410 420 430 440 450
FTQVTDSPAL VQAQINSKQL SDLNYKAKHE SEKSKYSIPP DAPFILQSRV
460 470 480 490 500
NAYNLSDNCY KYDWEQAKAK KFDIKMDAIP ILAAKANRKI ASDVEYKKGY
510 520 530 540 550
EQSKGKLIGA LSIQDDPKMV LSQKVAKLQS DRLYKEAYEK SKGISINYCD
560 570 580 590 600
TPKYQVDNVL KNFSEVKYKE PYVNNVLGRY IGTFEDPYQA HCMRIEAMKS
610 620 630 640 650
DKNYKADYEE DKGKCYFPQT ITQEYEAIKK LDQCKDYTYK KHPDQIKFTS
660 670 680 690 700
VMDSPVLLQA QINSKQLSDL NYKAKHENEK FKCSVPADAP LFLQSRVNAY
710 720 730 740 750
NLSDNWYKYD WEQSKAKKFD IKMDAIPILA AKANRKIASD VEYKKAYEQS
760 770 780 790 800
KGKLIGALSI EDDPKMVLSR KVAKLQSDRE YKKGYEESKT RYTAPMDMIS
810 820 830 840 850
VVQAKKAQAI VSDTDYKRFI HTYSYPPDSI PVELAKKANV IQSDNEYKAD
860 870 880 890 900
YNSWMKGCGW VPFGSMDAEK NKRASDILNE KKYRQHPDTL KFTQIDDDPI
910 920 930 940 950
VVQAKINQAQ RSDVLYKAKN EDVIHKYHLP ADAPQFIQAK VNSYNISDTY
960 970 980 990 1000
YKLGLEELKS KGYDLRIDAI PIKAAKAARH AASDFQYKKD YELGKGKLVG
1010 1020 1030 1040 1050
FRSLQDDPKL VHYMNVAKMQ SDREYKKSYE ESKTKYNTPL DMVNIVAAKN
1060 1070 1080 1090 1100
AQDIASNTNY KRLVHHYTFL PDAISVERSK NMMQIQSDNL YKADYNSWMK
1110 1120 1130 1140 1150
GIGWIPIGSL DVEKAKKAGD ALNEKKYRQH PDTIKFTSVV DSPVMVQAKQ
1160 1170 1180 1190 1200
NALQLSDRLY KSSGEEMKHT YHLTTDAPQF IQAKYNAANI SDTYYKLGYN
1210 1220 1230 1240 1250
ELIAKGHNVL GDAIPITLAK ASRNIASDYK YKEAYEKARG KHVGFRSLQD
1260 1270 1280 1290 1300
DPKLVHSMNV AKMQSEREYK KDYEKSKTCY HTPVEMVSIQ AAKQAQDVTS
1310 1320 1330 1340 1350
NCNYKRLIHH YTYLPDAMSV QLARNMNQIQ SDNIYKEDYK SWFKGIGWSP
1360 1370 1380 1390 1400
LGSLDVETAR KAGEAVSEIK YRQHPDKLKF TSLLDSMPMV LAQKNTQQMS
1410 1420 1430 1440 1450
DLNYKEAGEK LKHKYHLDPD VPQFIQAKVN ALNISDTCYK ADWKKIIAKG
1460 1470 1480 1490 1500
YDLKADAIPI IAAKASRNIA SDYKYKESYE KDKGKQVGFR SLQDDPKLVH
1510 1520 1530 1540 1550
YMNVAKLQSD REYKKDYEIS KTKYHSPLDM FSVTAAKKGQ EVVTDINYRQ
1560 1570 1580 1590 1600
RLHNYTLLPD AMSVELSRNR MQIQSDNLYK TDFNNWLRGV GWVPIQSLEV
1610 1620 1630 1640 1650
EKAKNATNIL NEKNYRQHPD KLKYTIDMNA MEQVLAKQNA QTMNKRLYIE
1660 1670 1680 1690 1700
KWNKDKTDIH VMPDTPEILL SKANQVTMSN KLYRSGWEED KKKGYDLRPD
1710 1720 1730 1740 1750
AISIKAARAS RDIASDYKYK LAFEQSKGKH IGFRSLEDDP KLVHFMQVAK
1760 1770 1780 1790 1800
MQSEREYKKD YEKSKTRFHT PVDMFSVIAA KKGQEVATDI NYRNIIHTYN
1810 1820 1830 1840 1850
VLPDSMNLVL AKNMMQIQSD NQYKADYDEF MKGVGWVPLG SLEAEKNRKA
1860 1870 1880 1890 1900
MEIVSEKKYR QHPDKLKYSI LMDSMPMVLA TSNAKIMDEH LYKKNWEADK
1910 1920 1930 1940 1950
INIHITPDTP EILLAKANAF NISNKMYTLS LEEAKKKGCD IRADAIPIQA
1960 1970 1980 1990 2000
AKASRDIVSD YKYKLGYEKD KGKLVGFRSL QDDPKLVHYM QVAKMQSDRE
2010 2020 2030 2040 2050
YKKAYETSKT RYNTPADTFS VMAAKEAQAN ITNTNYKRLI HKYILLPDAL
2060 2070 2080 2090 2100
HVELARNMNR IQSEHEYKQD YNEWYKGLGW SPAGSLEIEK SKKSTEIASD
2110 2120 2130 2140 2150
TKYRQHPSRF PFKKMTDSMD MELAKHNAGI MNKHAYIEAW EKDKTKIHVM
2160 2170 2180 2190 2200
PDTPDIMLSK ANKFNYSEKL YKLGYEEMLK KGYDLTAEAI SVKAAKASRD
2210 2220 2230 2240 2250
IASEYKYKEG YRKQLGHHVG ARSIQDDPKL VHSMNVAKIQ SEREYKKDFE
2260 2270 2280 2290 2300
KSKTRYTTPV DMLGVLLAKN CQKLVSDVDY RHHLHQWTCL PDQNDVIHAK
2310 2320 2330 2340 2350
KVYELQSNNA YKADLEWLKG IGWNTFGSLE SETQKKASEI LSEKKYRQHP
2360 2370 2380 2390 2400
DTIKFTSIPD SMEVILAKEN SKHRSDRLYR EAWDKDKTEV HIMPDTPEII
2410 2420 2430 2440 2450
LSRSNLINTS DKIYKLGYEE LKKKGYDLPP DAIPLKAAKA SRDIASEYKY
2460 2470 2480 2490 2500
KEAYRKQLGH HVGARSIQDD PKLVHSMNVA KLQSEREYKK DFEKSKTRYT
2510 2520 2530 2540 2550
SPVDMLGVLL AKNCQKLVSD VDYRHYLHQW TCLPDQNDVV HARKTYDLQS
2560 2570 2580 2590 2600
DNMYKADLEW LKGIGWSPSG SLEAEKNKKA SQILSDYLYR QHPDTLKFTS
2610 2620 2630 2640 2650
PIDSIPMALA KHNSEIMNHH MYVDAWNKDK TSIHIMPDTP EIILSQQNKI
2660 2670 2680 2690 2700
NYSEKLYKLA LEESKKKGYD LRVDAIPIKA AKASRDIASE YKYKEGYRKQ
2710 2720 2730 2740 2750
LGHHVGARSV QDDPKLVHCI NVAKMQSERE YKKDFEKSKT RYTSPVDMLG
2760 2770 2780 2790 2800
VLLAKNCQKL VSDVDYRHHL HQWTCLPDQN DVIQARKAYD LQSDNYYKSD
2810 2820 2830 2840 2850
LQWMKGIGWV PIGSLDTEKA KKAGEILSEK LYRQPPDKFK FTSVTDSLEM
2860 2870 2880 2890 2900
ELAKHNAETM NKRLYTEAWD KDKTQIHIMP DTPEITLARQ NKLNYSESLY
2910 2920 2930 2940 2950
KLALEEAKKR GYDLRLDAIP IQAAKASRNI ASDYKYKEGY RKQLGHHVGA
2960 2970 2980 2990 3000
RSVQDDPKLV HCINVAKLQS EREYKKDFEK SKTRYTSPVD MLGVLLAKNC
3010 3020 3030 3040 3050
QKLVSDVDYR HHLHQWTCLP DQNDVIQARK AYDLQSDNYY KSDLQWMKGI
3060 3070 3080 3090 3100
GWVPIGSLDT EKAKKAGEIL SEKLYRQPPD KFKFTSVTDS LEMELAKHNA
3110 3120 3130 3140 3150
ETMNKRLYTE AWDKDKTTIH VMPDTPEIVL AKLNKLNYSE KLYKLAMEEA
3160 3170 3180 3190 3200
KKEGYDLRVD AIPIQAAKAS RNIASDYKYK EGYRKQLGHH VGARSVQDDP
3210 3220 3230 3240 3250
KLVHSINVAK MQSEREYKKD FEKSKTCYSS PVDMLGILLA KNCQKLVSDI
3260 3270 3280 3290 3300
DYRHYLHQWI CLPDQNDVIQ ARKAYDLQSD AVYKQDLEWL KGIGWVPAGS
3310 3320 3330 3340 3350
LEVEKVKRAG EILSEKKYRQ PPDQIKFTSV ADSLEIELAK HNAEVMSKRL
3360 3370 3380 3390 3400
YTEAWDADKR TIHVMPDTPE IMLAKANSAN ISQKQYIQGW EEAKVKGYDL
3410 3420 3430 3440 3450
RADAIPIRSA KASRDIASDY KYKDAYEKQR GHYVGVKCLQ DDPKLVWFTH
3460 3470 3480 3490 3500
VAKIQSDREY KKDFEKWKTK IHSPVDMLSV LLAKNCQKLV SDVDYRRYLH
3510 3520 3530 3540 3550
EWTCLPDQND VIQAKKVYDL QSDNVYKSDL EWLRGIGWIP VGSLEVQKVK
3560 3570 3580 3590 3600
KAQEILNDRL YRQRPESVKF TSIVDSPDIV LAKANALLQS GALYREVWDK
3610 3620 3630 3640 3650
EKTQFTLPSD TPEMVLSKAN ALNVSKKYYQ SGWEEAKKKG YDLRLDAIEI
3660 3670 3680 3690 3700
QHAKASRNIA SEYKYKEGYR RQLGHHVGAR SIEDDPKLVL AMNVAKMQSE
3710 3720 3730 3740 3750
REYKKYFEKF KTKFNSPVDM LSLLLAKNCQ KLVSDIDYRH YLHEWTCLPD
3760 3770 3780 3790 3800
QNDVIQAKKA YELQSDNAYK ADLEWLRGIG WMPEGSVEVL KVKKAQEILN
3810 3820 3830 3840 3850
DRLYKQPPDA LKFTSIADPP PVVLAKINAQ QISENLYREA WDKEKTQFHL
3860 3870 3880 3890 3900
PSDTPVMLQA KINALTISNK YYTGDWDEAK AKGYDIRADA ISIKHAKASR
3910 3920 3930 3940 3950
EIASEYKYKE AHEKQKGHYI GSPSVKADPK LSWAAKVLKM QNDRLYKQAY
3960 3970 3980 3990 4000
NNSKAKITIP VDMVAIQSAK QCQSLVSEVD YRRRLHQWSC LPDQNDVIQA
4010 4020 4030 4040 4050
RKAYELQSDA VYKSDLEWLR GVGWVPTESP IVKRVKFAQD ILSDNVYRTP
4060 4070 4080 4090 4100
AERLKFTSIV DTPEILLAKT NAEQLSLAKY REVWDKDKTM IHVMPDTPEI
4110 4120 4130 4140 4150
MLSRANAVNV SHKLYKEAWD DIKKFIDYRA DAVPIKTAKA SREIASDYKY
4160 4170 4180 4190 4200
KEGYRRQLGH HVGARSIEDD PKLVLAMNVA KMQSEREYKK YFEKFKTKFN
4210 4220 4230 4240 4250
SPVDMLSLLL AKNCQKLVSD IDYRRYLHEW TCLPDQNDVI QAKKAYELQS
4260 4270 4280 4290 4300
DAVYKSDLEW LRGIGWMPND SVSVNHVKHA QDILSERQYR TKVDSQPFTP
4310 4320 4330 4340 4350
VADRPDYTTA KQGGEILSDI KYHQEWNNIK TNYTLTETPQ LEAAKEAARI
4360 4370 4380 4390 4400
LNHNLYKENW EKAKATGYLL PADSVPIRHA KHSSDVQSEM KYKADYISQR
4410 4420 4430 4440 4450
GHYVGVNNMR EDPKLVWFEH AGKIQNDRLY KEAYNKTKSK IHIPPDIVSV
4460 4470 4480 4490 4500
VAAKDCQHVV SEIPYRHYLH EWTCHPDQND CIQARKAYDL QSDNLYKSDL
4510 4520 4530 4540 4550
EWIRGCGWIP LDSVEHRKVK NAQNLTNKVN RLYVKEAVDN FANFTPVEDP
4560 4570 4580 4590 4600
PEIVLAKANA INQSDLKYKE TFNLEKGHYI GSDDTPALSH SRDMAKLYSD
4610 4620 4630 4640 4650
FVYKDAWQQG KAIGYTLPPD YIPIVGAKHA DYVNSQLKYK ETYEKQKGHY
4660 4670 4680 4690 4700
LAGAEINDFP SVVHSLAFQK IRSALAYRKN YEDNKAHIHI PGDMINHVLA
4710 4720 4730 4740 4750
KKCQYILSDL EYRTYLHQWN CSPEEHDVIM ARRAQEILSD VLYKDDLTWL
4760 4770 4780 4790 4800
KGIGCYVWDT PQILHAKKSY DLQSQLKYTK AGKDNLENYS VVMDTPVYVT
4810 4820 4830 4840 4850
SIQSTINASD VKYKEEYHKM KDQYTTVLET VDHERTQNLK HLFSSNLYKE
4860 4870 4880 4890 4900
AWDKLKSTSF TLPPDAVPLV RAKELKHNAS IVKYREEYDK FKALYTLPKG
4910 4920 4930 4940 4950
VQDDPNTARC LRVGKLNLDR LYRETYEKNK AKIHIVPDMV DIVSAKSTQK
4960 4970 4980 4990 5000
KVSEVDYRIH LHEWTNIPDL HENALARKVY AQLSDVVYKD DLNWLKGIGC
5010 5020 5030 5040 5050
FVWDTPEILH AKHAYDLRDD FKYKAKAEKM KSKYTVVMDT PVYVQNVQSG
5060 5070 5080 5090 5100
LNLSEAVYRH DYVKNIRGKY TPVDKTVDLD RATNAYKIQN EGLYRKAGLH
5110 5120 5130 5140 5150
ALPTGYKLPA DTPGFKHAKH AQYIGSYLKY KEVYEHIKAK GYNFGPKAVP
5160 5170 5180 5190 5200
FVTTRKVNKI LNERLYREAY HKNKDKIHTT PDTPAIRQVK TNQESISDLI
5210 5220 5230 5240 5250
YRTDFFKMQG HQISMPYTPQ TIHSRYVGEI TSDVKYKGDL QWLRGLGCLL
5260 5270 5280 5290 5300
YDTPDMVRAR HLRKLWSNYV YSESAKKTLD KYRVVLDTPV YRTIQELKTH
5310 5320 5330 5340 5350
LSEITYIITT KFLNTLFSIV PNRVSLIQHK RAGRMLDKYL YIELATKERP
5360 5370 5380 5390 5400
HHHAGNQTTA LQLAKHVKDF ASEKKYKAQY NKLKHKYVTI PDTPFLVMAK
5410 5420 5430 5440 5450
KSYLNASDLR YKETFEKAKG KYHTVKDALD IVYHRKVTDD ISKVKYKEKY
5460 5470 5480 5490 5500
ISQLGIWRSI PDWPDHFHHR AVTDAVSDVK YKDDLTWLRG IGCYAWDTPD
5510 5520 5530 5540 5550
LLLAGKNKTL YSPCKYKESF EKMKSKFQYV ADTPINRHVK YATQLANEKL
5560 5570 5580 5590 5600
YKSDYEKKKD KYSLVVDDPK TLLAKWGGEL SSQYKYKRLY EKQKDKFTSI
5610 5620 5630 5640 5650
VDTPEHLRTT KVNKQISDIL YKLEYNKAKP KGYTAIHDTP MVLHVRKVMD
5660 5670 5680 5690 5700
RISELKYKEI YEQNKSHIHI VPDSVHIKAA KQAYKVNTNL DYKKKYEATK
5710 5720 5730 5740 5750
AHWQWTVDRP DFIQAAKSSL QQSDYEYKLD REWLRGCKLS VTDDKNTVLA
5760 5770 5780 5790 5800
LQNAILASDL KYKEKHNKER GTIHAVADTP QILLAKSVSS LVSENKYKEH
5810 5820 5830 5840 5850
AKKNRPHGSF TKLPETRDTV HVKEVTKNVS ETNYKKKFQK EKGKSNYSIM
5860 5870 5880 5890 5900
LEPPEVKHAI EVAKNQSNIQ YKKDAKSKLH YTSVADRPDI KKATQVSHLV
5910 5920 5930 5940 5950
SDIEYKAKAR GEAGMGVSML GRPDIELAKE VSKLTSQLKY KERFDKEKGK
5960 5970 5980 5990 6000
KPQYDLKESK IYKTLKDAHN IASEIKYKTD LKKLHKPVTD MSESLAMNHV
6010 6020 6030 6040 6050
LSTSQLASSY QYKKKYEKSK GHYHVVPDNL EQIHLKEASE LQSIVKYKEK
6060 6070 6080 6090 6100
YEKERGKPML DFETPTYLTA KESQHMQSEK EYKKDYEESI KGRNLSGLEI
6110 6120 6130 6140 6150
TPSLLHVRYA TKIASEKEYR RDLEEGVKGK GLTIVDETPE LLRAKNATCI
6160 6170 6180 6190 6200
LNEKEYRRAL DMEIKGRGLT SLALETPDYM RAKNAMDIAS QVKYKQSAEM
6210 6220 6230 6240 6250
EKANYTTVVD TPDIIHAQHV KSFYSQKKYK EDAERTMSYY VPVLETPEMQ
6260 6270 6280 6290 6300
RVRENQKNFS MIGYNCFFPG NSVGIDSRTG TDPWTLTLVT LSRNAKTILY
6310 6320 6330 6340 6350
KEDIGTGTAI EKTPEMQRIK QTQDAISTIK YKEQIGKGTP ISDLPEVKRV
6360 6370 6380 6390 6400
KETQKNISSV LYKENLGTGI PTPITPEMER VKRNQENFSS VLYKEEMGKG
6410 6420 6430 6440 6450
TPTPVTPEME RVKRNQEHIS SVLYKEEMGK GTPTPVTPEM ERVKRNQEHI
6460 6470 6480 6490 6500
SSVLYKEGMG KGTPTPVTPE MERVKRNQEY ISSVLYKEGL GKGTPTPITP
6510 6520 6530 6540 6550
EMERVKRNQE NISSVLYKES LGKGTPAPVT PEMERAKRNQ ENISSVLYSD
6560 6570 6580 6590 6600
SFRKQVQGKA AFVLDTPEMR RVRETQRHIS TVKYHEDFEK SKGSFTPVVT
6610 6620 6630 6640 6650
DPIMERVKKN MQDFSDINYR GIQRRVVEME RKRIDNDQDF TDLRVWRTNP
6660 6670 6680 6690 6700
GSVFDYDPAE DNIQSRSLHL INVQAQRRSR EQSRSASALS LSAGDEKSEH
6710 6720 6730 6740 6750
SEAADQHLSY YSNGGFYTTT GTVEYKHAKT IELPQQRSSS VATQQTTVSS
6760 6770 6780 6790 6800
IPSHPSTAGK TYRAMYDYTA SDADEVSFKD GDALVNVQAI DEGWMYGTVQ
6810
RTGQTGMLPA NYVEAL
Length:6,816
Mass (Da):788,721
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i040B1CF1C4C2DCD8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AAWZ02024000 Genomic DNA No translation available.
AAWZ02024001 Genomic DNA No translation available.
AAWZ02024002 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSACAT00000003917; ENSACAP00000003825; ENSACAG00000003769

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02024000 Genomic DNA No translation available.
AAWZ02024001 Genomic DNA No translation available.
AAWZ02024002 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000003825

Genome annotation databases

EnsembliENSACAT00000003917; ENSACAP00000003825; ENSACAG00000003769

Phylogenomic databases

eggNOGiKOG1702, Eukaryota
GeneTreeiENSGT00940000154533
HOGENOMiCLU_000024_0_0_1
InParanoidiH9G895
OMAiHSPVDMM

Gene expression databases

BgeeiENSACAG00000003769, Expressed in skeletal muscle tissue and 9 other tissues

Family and domain databases

CDDicd11933, SH3_Nebulin_C, 1 hit
InterProiView protein in InterPro
IPR013998, Nebulin-like
IPR000900, Nebulin_repeat
IPR035629, Nebulin_SH3
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
PfamiView protein in Pfam
PF00880, Nebulin, 71 hits
PF14604, SH3_9, 1 hit
PRINTSiPR00510, NEBULIN
SMARTiView protein in SMART
SM00227, NEBU, 184 hits
SM00326, SH3, 1 hit
SUPFAMiSSF50044, SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS51216, NEBULIN, 187 hits
PS50002, SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9G895_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9G895
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 7, 2020
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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