UniProtKB - H9G7U9 (H9G7U9_ANOCA)
Protein
Complex I-49kD
Gene
NDUFS2
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Cofactori
[4Fe-4S] clusterARBA annotation
GO - Molecular functioni
- 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
- NAD binding Source: InterPro
- NADH dehydrogenase (ubiquinone) activity Source: GO_Central
- quinone binding Source: InterPro
- ubiquitin protein ligase binding Source: Ensembl
GO - Biological processi
- mitochondrial electron transport, NADH to ubiquinone Source: GO_Central
- response to oxidative stress Source: Ensembl
Keywordsi
Biological process | Electron transportARBA annotation, Transport |
Ligand | 4Fe-4SARBA annotation, Iron, Iron-sulfur, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Complex I-49kDARBA annotationAlternative name(s): NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialARBA annotation NADH-ubiquinone oxidoreductase 49 kDa subunitARBA annotation |
Gene namesi | Name:NDUFS2Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Mitochondrion
- mitochondrial respiratory chain complex I Source: GO_Central
Nucleus
- nucleoplasm Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000003534, Expressed in heart and 14 other tissues |
Interactioni
GO - Molecular functioni
- ubiquitin protein ligase binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000003559 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 256 | Complex1_49kDaInterPro annotationAdd BLAST | 255 |
Sequence similaritiesi
Belongs to the complex I 49 kDa subunit family.ARBA annotation
Phylogenomic databases
eggNOGi | KOG2870, Eukaryota |
GeneTreei | ENSGT00390000009529 |
HOGENOMi | CLU_015134_6_0_1 |
InParanoidi | H9G7U9 |
OMAi | DQSIFPW |
TreeFami | TF300370 |
Family and domain databases
Gene3Di | 1.10.645.20, 1 hit |
InterProi | View protein in InterPro IPR001135, NADH_Q_OxRdtase_suD IPR038290, NADH_Q_OxRdtase_suD_sf IPR029014, NiFe-Hase_large |
Pfami | View protein in Pfam PF00346, Complex1_49kDa, 1 hit |
SUPFAMi | SSF56762, SSF56762, 1 hit |
i Sequence
Sequence statusi: Complete.
H9G7U9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
QMFEFYERVS GARMHAAYVR PGGVHQDMPL GLMDDIYEFV KNFSIRIDEV
60 70 80 90 100
EEMLTNNRIW KNRTVDIGVV TSEEALNYGF SSGVMLRGSG IQWDLRKSQP
110 120 130 140 150
YDVYDQVEFD VPIGSRGDCY DRYLCRVEEM RQSLRIIVQA LNKMPEGEVK
160 170 180 190 200
VDDAKISPPK RAEMKTSMEA LIHHFKLYTE GYQVPPGATY TAIEAPKGEF
210 220 230 240 250
GVYLVSDGSS RPYRCKIKAP GFAHLAGLDK MSQGHMLADV VAIIGTQDIV
FGEVDR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02029570 Genomic DNA No translation available. AAWZ02029571 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSACAT00000003647; ENSACAP00000003559; ENSACAG00000003534 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAWZ02029570 Genomic DNA No translation available. AAWZ02029571 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000003559 |
Genome annotation databases
Ensembli | ENSACAT00000003647; ENSACAP00000003559; ENSACAG00000003534 |
Phylogenomic databases
eggNOGi | KOG2870, Eukaryota |
GeneTreei | ENSGT00390000009529 |
HOGENOMi | CLU_015134_6_0_1 |
InParanoidi | H9G7U9 |
OMAi | DQSIFPW |
TreeFami | TF300370 |
Gene expression databases
Bgeei | ENSACAG00000003534, Expressed in heart and 14 other tissues |
Family and domain databases
Gene3Di | 1.10.645.20, 1 hit |
InterProi | View protein in InterPro IPR001135, NADH_Q_OxRdtase_suD IPR038290, NADH_Q_OxRdtase_suD_sf IPR029014, NiFe-Hase_large |
Pfami | View protein in Pfam PF00346, Complex1_49kDa, 1 hit |
SUPFAMi | SSF56762, SSF56762, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H9G7U9_ANOCA | |
Accessioni | H9G7U9Primary (citable) accession number: H9G7U9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 16, 2012 |
Last sequence update: | May 16, 2012 | |
Last modified: | December 2, 2020 | |
This is version 46 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |