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Entry version 49 (07 Oct 2020)
Sequence version 1 (16 May 2012)
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Protein

PDZ domain-containing protein

Gene

AHNAK

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PDZ domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AHNAKImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000003562, Expressed in skeletal muscle tissue and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000003467

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 79PDZInterPro annotationAdd BLAST79

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20
Regioni974 – 996DisorderedSequence analysisAdd BLAST23
Regioni1098 – 1121DisorderedSequence analysisAdd BLAST24
Regioni1227 – 1249DisorderedSequence analysisAdd BLAST23
Regioni1352 – 1372DisorderedSequence analysisAdd BLAST21
Regioni1546 – 1566DisorderedSequence analysisAdd BLAST21
Regioni1662 – 1683DisorderedSequence analysisAdd BLAST22
Regioni1789 – 1831DisorderedSequence analysisAdd BLAST43
Regioni2011 – 2032DisorderedSequence analysisAdd BLAST22
Regioni2215 – 2236DisorderedSequence analysisAdd BLAST22
Regioni2275 – 2307DisorderedSequence analysisAdd BLAST33
Regioni3094 – 3126DisorderedSequence analysisAdd BLAST33
Regioni3156 – 3201DisorderedSequence analysisAdd BLAST46
Regioni3242 – 3275DisorderedSequence analysisAdd BLAST34
Regioni3459 – 3478DisorderedSequence analysisAdd BLAST20
Regioni3517 – 3551DisorderedSequence analysisAdd BLAST35
Regioni3937 – 3958DisorderedSequence analysisAdd BLAST22
Regioni4192 – 4217DisorderedSequence analysisAdd BLAST26
Regioni5178 – 5277DisorderedSequence analysisAdd BLAST100

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1235 – 1249PolyampholyteSequence analysisAdd BLAST15
Compositional biasi2015 – 2032PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2219 – 2236PolyampholyteSequence analysisAdd BLAST18
Compositional biasi3101 – 3126PolyampholyteSequence analysisAdd BLAST26
Compositional biasi3164 – 3201PolyampholyteSequence analysisAdd BLAST38
Compositional biasi3461 – 3478PolyampholyteSequence analysisAdd BLAST18
Compositional biasi3939 – 3958PolyampholyteSequence analysisAdd BLAST20
Compositional biasi5194 – 5211PolyampholyteSequence analysisAdd BLAST18
Compositional biasi5234 – 5261PolarSequence analysisAdd BLAST28

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QTQ3, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154902

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_223458_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H9G7Q6

Identification of Orthologs from Complete Genome Data

More...
OMAi
PGPDMRG

TreeFam database of animal gene trees

More...
TreeFami
TF344181

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001478, PDZ
IPR036034, PDZ_sf

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156, SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106, PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9G7Q6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKEEEGPRE ILLPDWQGSG SHGITLDQTE EGVFVKQVHE DSPIAKTGVV
60 70 80 90 100
KEGDQIVSAT IYFDNLQSGE VNELLRNVGH HTVGLRVQRK GDRSPLPGQT
110 120 130 140 150
WSHDVFVPQT PEVVLSGDDE EYRRIYTTKI KPRLKSEDGV ETEAAGGTQS
160 170 180 190 200
RTITVTKRVT AYTVDVGGRE GARDLDLTSP EFKIKVPKHE LSHVSKAEFE
210 220 230 240 250
TEPGKIMTTT TTMTTTTIKI PQIDPVQGRP SEVTFAGPSV DSPSQRLEFG
260 270 280 290 300
VPDIRMEQSK VQISGPQISG PGLTITSPEI NGKMSGVSVD ISGPQIGGMK
310 320 330 340 350
APGSPGSLSF PAMKMPKFGI GSSALDVEVP QLDTSAPSVT IKGPDGSFKG
360 370 380 390 400
PKYTLGGSGD LHWKEGVKVA SPTLEGPKVD LKGPKVGFVE PDVGEGKIKL
410 420 430 440 450
PHMKLPKFSA SGPTVDASAP KGGIEISGPQ MDIQAPDVAL EAHVKGPKFG
460 470 480 490 500
HPEVVSQIPS ISMSDVDLSL KAPSLKGDMD ISVPKLEGGL KGPQVGIKGP
510 520 530 540 550
QVDVGIKGPS GQLKGLHIKA PQISIPDIDL NVKAPKVKGD LGVSVPKVEG
560 570 580 590 600
GLKGPVVDIK GPNVDLGAPS VDLHRPELKM PKMKLPKFGI QGEVPNVDVS
610 620 630 640 650
LPKGSVDISG PNVDVEAPTF GIKGPAGHLK GGPHVNVPEM HVKTPHITIP
660 670 680 690 700
DIDLNLQGPN LKGDVDVSLP KFEGGIKGPA VDLKGPEVDL GAPNVEFHGP
710 720 730 740 750
DFKMPKLKMP KFGMPGFKAE APDVEIGLPK GSVDISSPQL DIDAPNIGVK
760 770 780 790 800
GGQLKGPHVK MPQISIPDID LNLKAPKLKG DVDVSIPKVE GGLKGPTMDI
810 820 830 840 850
KGPKLDVGAP DVGLHGPELK MPKMKLPKFG VKGEVPDVDV TLPKGSIDIS
860 870 880 890 900
GPKVDVEAPT LGIKGPAGHL KGPHVKMPEM HVKTPHITIP DIDLNLQGPN
910 920 930 940 950
LKGDVDVSLP KVGGGLKGPA VDLKGPQVDF AAPDVDFHGP ELKMPKMKMP
960 970 980 990 1000
KFGIQGEVPD VDVGLPKGGL DISAPRVDLE GPELGFEGPE GKIKGHRFKM
1010 1020 1030 1040 1050
PEMPKISMPD IDLNLKGPRA KGGLDVSVPK VKGDFKGPRL DLEGPQLDVD
1060 1070 1080 1090 1100
VPDVELHGPE GKLKMPKMKM PKFGMPGFKG EAPDVDLSLP KGGINISGPK
1110 1120 1130 1140 1150
VDIDAPELEM EGPDVNIKGP KFRMPEMHMK TPKISMPDID LNLKRPKVKG
1160 1170 1180 1190 1200
EVDVSVPKLE GGLKSPEVDI KGPKLDVDIP DVDLQGPEGK LKMPKFKMPK
1210 1220 1230 1240 1250
FGMPSFKGEG PEVDVNLQRP DVDVSLPKVD VEGPSLDIEG PEGKLKGPKF
1260 1270 1280 1290 1300
RMPEMHIKAP KISMPDVDLN LKGPKWKGDV DISGPKVEGE LKGPSIDIKG
1310 1320 1330 1340 1350
PKLDVDVPDI DLEGPEAKLK MPKMKMPKFG IPGFRAEGPD VDVSLPKGEL
1360 1370 1380 1390 1400
DVDMPSVGVE GPEGKLKGPK FKMPEMHFKT PKISMPDVDL NLKGPKLKGD
1410 1420 1430 1440 1450
VDVSVPKLEG ELKGPNVDIK GPSVDFSAPD MDLQGEGKLK MPKLKMPHFS
1460 1470 1480 1490 1500
VSGPKLEGPD VDVNLPKGDL DFAGPKMDVE APDIDIEGPE GKLKGSRFKM
1510 1520 1530 1540 1550
PKLNIKAPKI SMPDVDLHLK GPGSRGEMDV TVPNLEADLK GPKVDLKAPD
1560 1570 1580 1590 1600
VSLEGPEGKL KGPKFKMPDM HFKTPHISMP DIDLNLKGPK LKGDVDVSLP
1610 1620 1630 1640 1650
KVEGPDVDIK GPKLDLDAPD VELHGPEGKL KMPKFKMPKF GMPGFRAEGP
1660 1670 1680 1690 1700
DVDVSLPKAD LEGDFEGPSL DIEGPEGKVK GPRFKMPEMH IKAPKISMPD
1710 1720 1730 1740 1750
VDFNLRGPKL KGDVDVSVPK LEGDLKGPNI DIEGPKLDID APAVDIEGPE
1760 1770 1780 1790 1800
GNWKTPKFKM PEMNIKAPKI SMPDVDFNLR GPKIKGDVDV SAPKLEGPDI
1810 1820 1830 1840 1850
DIKGPKLDID APDVDLHGPE GKVKGPKFRM PDMHFKTPKI SMPDIDLNLK
1860 1870 1880 1890 1900
GPKVKGDVDV SVPKLEGDLK GPNIDIHGPK LDVDVPDVEL EGPEGKLRGP
1910 1920 1930 1940 1950
KFKMPDMHFK APKISMPDVD FNLKGPKLKG DLDVSVPKLE GDLKGPDFDI
1960 1970 1980 1990 2000
KGPKLDIDAP DVDLHGPEGK LKMPKFKMPK FGMPSFKGEG PDVDLSLPKA
2010 2020 2030 2040 2050
DVDASLPKVD LEGPSLDVEG PEGKLKGPKF KMPDMHFKTP KISMPDIDLN
2060 2070 2080 2090 2100
LKGPKLKGDV DVSVPKVEGD LKGPDFNIKG PKLDVDLPDV DLEGPEGKLK
2110 2120 2130 2140 2150
GPKFKMPEMH IKAPKISMPD FDLSLKGPKV KGDVDVSIPK LEGDLKGPDV
2160 2170 2180 2190 2200
DLKGPKVDLD IPDVELEGPE GKWKAPKFKM PEMNIKAPKI SMPDFDLNLK
2210 2220 2230 2240 2250
GIDADIKGPQ LDIDVPDVSL EGPEGKVKGP KFKMPDMHFK TPKISMPDID
2260 2270 2280 2290 2300
LNLRGPKLKG DVDVSVPKLE GDLRGPDIDI KGPKLDIDAP DVEIEGPDGK
2310 2320 2330 2340 2350
WKGPKFKMPD MHFKTPKISM PDFDLNLKGP KVKGDVDVSV PKLEGDLKGP
2360 2370 2380 2390 2400
NIDIQGPKLD VDVPDVELEG PEGKLRGPKF KMPDMHFKAP KISMPDVDFN
2410 2420 2430 2440 2450
LKGPNWKGDV DVSLPKVEGP NIDLKGPKLD IDAPDVDLHG PEGKLKMPKF
2460 2470 2480 2490 2500
KMPKFGMPGF KGEGPEIDVN LPKGDIDVSA PKVDLEGPEL DIEGPEGKIK
2510 2520 2530 2540 2550
GPKFKMPEMH IKAPKISMPD VDFNLKGPKL KGDLDVSAPK LEGDLKGPDL
2560 2570 2580 2590 2600
DIKGPKVDID VPDVDLHGPE GKLKMPKFKM PKFGMPGFKG EGPEIDVSLP
2610 2620 2630 2640 2650
KGDIDVSAPK VDLEGPELDI EGPEGKIKGP KFKMPEMHIK APKISMPDVD
2660 2670 2680 2690 2700
FNLKGPKLKG DLDVSAPKLE GDLKGPDFDI KGPKVDIDVP DVDLHGPEGK
2710 2720 2730 2740 2750
LKMPKFKMPK FGMPGFKGEG PEIDVNLPKG DIDVSAPKVD LEGPELDIEG
2760 2770 2780 2790 2800
PEGKIKGPKF KMPEMHIKAP KISMPDVDFN LKGPKLKGDL DVSAPKLEGD
2810 2820 2830 2840 2850
LKGPDFDIKG PKVDIDVPDV DLHGPEGKLK MPKFKMPKFG MPGFKGEGPS
2860 2870 2880 2890 2900
VDVNLPKGEV DISAPKLDIE TPDLEIEGPE GKLKAPKFKK PDMHFNVPKI
2910 2920 2930 2940 2950
SMPDIDLNLR GPKIKGDVEG DIKGPNVELK GPDIDLEAPK IDIEAKPKKS
2960 2970 2980 2990 3000
RFKLPKFNFS GPKVHTPEVD VKLKKPDVDV SGPKLDVQGP DVDLQGKVKG
3010 3020 3030 3040 3050
SKFKMPSLNI SSPKVSVPDV ELNLKAPKLK GDLNVSSPSL EGDLKGPDID
3060 3070 3080 3090 3100
IKGPKLDIAA PDVDLHGPEA KLKMPKFKMP KFGMKGPEVD LNLPKADLDV
3110 3120 3130 3140 3150
TGPKMDIETP DLEIEGPEGK IKGSRFKMPD MNFEMPKISM PDIDLNLKGP
3160 3170 3180 3190 3200
KLKGGVDVSA PKLEGDLKGP DMDLKGPKLD ANLPDVEIEG PEGKLKGPKF
3210 3220 3230 3240 3250
KMPDLHFKAP KISMPDLDMN LKGPKLKGDV DVSVPKLEGD LKGPDVDIKG
3260 3270 3280 3290 3300
PKLDIDAPDV EIEGPDGKWK GPKFKMPDMH FKTPKISMPD IDLNLKGPKV
3310 3320 3330 3340 3350
KGDVDVSVPK LEGDLKGPNI DIQGPKLDVD VPDVELEGPE GKLRGPKFKM
3360 3370 3380 3390 3400
PELNIKAPKI SMPDVDFNLK GPKLKGDLDV SVPKLEGDLK GPDLDIKGPK
3410 3420 3430 3440 3450
LDIDAPDVDL HGPEGKLKMP KFKMPKFGMP SFKAEGPDVD VSLPKADLDV
3460 3470 3480 3490 3500
SLPKVDLEGP SLDVEGPEGK LKGPKFKMPD MHFKTPKISM PDIDLNLKGP
3510 3520 3530 3540 3550
KLKGDVDVSA PKLEGDLKGP DFDIKGPKLD IDAPDVEIEG PDGKWKGPKF
3560 3570 3580 3590 3600
KMPDMHFKTP KISMPDIDLN LKGPKVKGDV DVSVPKLEGD LKGPSVDIQG
3610 3620 3630 3640 3650
PKLDVDVPDV ELEGPDAKLR GPKFKMPEFN IKAPKISMPD VDFNLKGPKL
3660 3670 3680 3690 3700
KGDLDVSAPK FEGDLKGPEL DIKGPKLDID APDVDLHGPE GKLKMPKFKM
3710 3720 3730 3740 3750
PKFGMPGFKG EGPDVDVSLP KADLDVSLPK VDLEAPSLDV EGPEGKLKGP
3760 3770 3780 3790 3800
KFKMPDMHFK TPKISMPDFD LSLKGPKVKG DVDVSMPKLE GDFRGPDFDI
3810 3820 3830 3840 3850
KGPKLDVDVP DVELEGPDAK LRGPKFKMPE MNIKAPKISM PDVDFNLKGP
3860 3870 3880 3890 3900
KLKGDLDVSV PKLEGDLKGP DFDIKGPKLD IDAPDVDLHG PEGKLKMPKF
3910 3920 3930 3940 3950
KMPKFGMPGF KAEGPDVDVS LPKADLDVSL PKVDLEGPSL DVEGPEGKLK
3960 3970 3980 3990 4000
GPKFKMPDMH FKSPKISMPD MDFNLKGPKL KGDLDVSAPK FEGDLKGPDF
4010 4020 4030 4040 4050
DIKGPKVDID APDVDLHGPE GKLKMPKFKM PKFGMPGFKA EGPDVDVSLP
4060 4070 4080 4090 4100
KADLDVSLPK VDLEGPSLDV EGPEGKLKGP KFKMPDMHFK TPKFSMPDID
4110 4120 4130 4140 4150
LNLKGPKVKG DVDVSMPKLE GDFKGPDFDI KGPKLDVDVP DVDLEVPDPK
4160 4170 4180 4190 4200
LKGPKFKMPD MHFKTPKISM PDMNLNLKGP KVKGDMDVSV PKLEGDLKGP
4210 4220 4230 4240 4250
DVDIEGPDGK LKGPRFKMPE MNIKAPKISM PDMDFSLKGP KVKGDVDLDV
4260 4270 4280 4290 4300
SVPKIGGDLK GPDFDLKGPK VDVSVPDVDL ECPEGNLKGP KFKMPDMHFK
4310 4320 4330 4340 4350
TPKISMPDFD LNLKGPKVKG DVDVSAPKLE GPDFDIKGPK LDVDVPDVEL
4360 4370 4380 4390 4400
EGPDGKWKGP KFKMPEMHMK APKISMPDVD LNLKGPQMKG EGDFKGPEID
4410 4420 4430 4440 4450
IKGPKLDIDA PDVDLHGPKM KLPKMKLPKF GLSGFKGEGP DVDVNLPKGE
4460 4470 4480 4490 4500
LEFSGPKVNV EAPSLDVEGQ LKGPNVTMPE MHFKTPKISM PDIDLNLKGP
4510 4520 4530 4540 4550
KAKGDFNLKG PEMDLEGQGF GLKGPNIDLE CPDVNVEGPE GSVKLPKFKM
4560 4570 4580 4590 4600
PKFGFGAKSP KAEVKSPNLD VSLPEGDLSL ESPDVALSAK GKKSKFKMPK
4610 4620 4630 4640 4650
IHMSGPKIKG KKAGFDVSGE MDAGVKSPDL EGSISVPEAS LKGDLNVKSP
4660 4670 4680 4690 4700
KGKSVFGKLS FPDVEFDIKS PVFKADASLP KVEGDLKSPD LDITVPSLPD
4710 4720 4730 4740 4750
VNIGGPDVHM KKPKFHLSGG NVDLSGPKLE GDVQVPSFDA KLNAPDVNLK
4760 4770 4780 4790 4800
GPSVDIAAPS FSAPEVDLNL KGPKITGDVE VPHAELHGPE GKLKFPKFGK
4810 4820 4830 4840 4850
PGVKLDGPDV NLQGRSPSAS IDVSGLGGTG DLSFKGPKLG GDLGLSGDVK
4860 4870 4880 4890 4900
GPKVGFGGPE VNIGGFDGKF NLPKSPGLDV NVSAPDLDVK MSSSPDFDVN
4910 4920 4930 4940 4950
LKGPKVKGDL GFSGGISSPK FEGPQVNLEG GGGGGGVIRL PCMKLPQFGI
4960 4970 4980 4990 5000
SSEGDISGPG VDFQGPKLSA PDFDLNLKGP SLKGDVKVGT AGVKMPGMRF
5010 5020 5030 5040 5050
DAEAPDVSLR GPSLNVSAPK VSGPDFDVDV KGPKIKSPEF DGTGDLHVSG
5060 5070 5080 5090 5100
PKGGLGVKGP HGHLESPSGK VSFPKMKMPK FVVSGQEAAG REVGVDVEFP
5110 5120 5130 5140 5150
QATVLANVEL EEPDLKLKKS KIKMPKFAFS KPKAKGGEVS GGELKASLGS
5160 5170 5180 5190 5200
LEGDVEVGAE ASAASPKGKF SFFKTKKSRH RSSSFSDDHS SHSTPTGTLE
5210 5220 5230 5240 5250
HEGEKGKHGG AKLKFGTFGG IGSKNKGSYE VTGSDDEKTA SLASKKSRLS
5260 5270
SSSSNDSGTK AGFRVPSVEL TVAKKKE
Length:5,277
Mass (Da):565,286
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9F5239B2538848F5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AAWZ02034691 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSACAT00000003553; ENSACAP00000003467; ENSACAG00000003562

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02034691 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Protein-protein interaction databases

STRINGi28377.ENSACAP00000003467

Genome annotation databases

EnsembliENSACAT00000003553; ENSACAP00000003467; ENSACAG00000003562

Phylogenomic databases

eggNOGiENOG502QTQ3, Eukaryota
GeneTreeiENSGT00940000154902
HOGENOMiCLU_223458_0_0_1
InParanoidiH9G7Q6
OMAiPGPDMRG
TreeFamiTF344181

Gene expression databases

BgeeiENSACAG00000003562, Expressed in skeletal muscle tissue and 14 other tissues

Family and domain databases

Gene3Di2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR001478, PDZ
IPR036034, PDZ_sf
SMARTiView protein in SMART
SM00228, PDZ, 1 hit
SUPFAMiSSF50156, SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106, PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9G7Q6_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9G7Q6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 7, 2020
This is version 49 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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