Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - H9G7Q6 (H9G7Q6_ANOCA)

Entry version 49 (07 Oct 2020)
Sequence version 1 (16 May 2012)
Previous versions | rss
Add a publicationFeedback
Protein

PDZ domain-containing protein

Gene

AHNAK

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PDZ domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AHNAKImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000003562, Expressed in skeletal muscle tissue and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000003467

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 79PDZInterPro annotationAdd BLAST79

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20
Regioni974 – 996DisorderedSequence analysisAdd BLAST23
Regioni1098 – 1121DisorderedSequence analysisAdd BLAST24
Regioni1227 – 1249DisorderedSequence analysisAdd BLAST23
Regioni1352 – 1372DisorderedSequence analysisAdd BLAST21
Regioni1546 – 1566DisorderedSequence analysisAdd BLAST21
Regioni1662 – 1683DisorderedSequence analysisAdd BLAST22
Regioni1789 – 1831DisorderedSequence analysisAdd BLAST43
Regioni2011 – 2032DisorderedSequence analysisAdd BLAST22
Regioni2215 – 2236DisorderedSequence analysisAdd BLAST22
Regioni2275 – 2307DisorderedSequence analysisAdd BLAST33
Regioni3094 – 3126DisorderedSequence analysisAdd BLAST33
Regioni3156 – 3201DisorderedSequence analysisAdd BLAST46
Regioni3242 – 3275DisorderedSequence analysisAdd BLAST34
Regioni3459 – 3478DisorderedSequence analysisAdd BLAST20
Regioni3517 – 3551DisorderedSequence analysisAdd BLAST35
Regioni3937 – 3958DisorderedSequence analysisAdd BLAST22
Regioni4192 – 4217DisorderedSequence analysisAdd BLAST26
Regioni5178 – 5277DisorderedSequence analysisAdd BLAST100

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1235 – 1249PolyampholyteSequence analysisAdd BLAST15
Compositional biasi2015 – 2032PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2219 – 2236PolyampholyteSequence analysisAdd BLAST18
Compositional biasi3101 – 3126PolyampholyteSequence analysisAdd BLAST26
Compositional biasi3164 – 3201PolyampholyteSequence analysisAdd BLAST38
Compositional biasi3461 – 3478PolyampholyteSequence analysisAdd BLAST18
Compositional biasi3939 – 3958PolyampholyteSequence analysisAdd BLAST20
Compositional biasi5194 – 5211PolyampholyteSequence analysisAdd BLAST18
Compositional biasi5234 – 5261PolarSequence analysisAdd BLAST28

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QTQ3, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154902

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_223458_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		H9G7Q6

Identification of Orthologs from Complete Genome Data

More...OMAi		PGPDMRG

TreeFam database of animal gene trees

More...TreeFami		TF344181

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001478, PDZ
IPR036034, PDZ_sf

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50156, SSF50156, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50106, PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9G7Q6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKEEEGPRE ILLPDWQGSG SHGITLDQTE EGVFVKQVHE DSPIAKTGVV 
        60         70         80         90        100
KEGDQIVSAT IYFDNLQSGE VNELLRNVGH HTVGLRVQRK GDRSPLPGQT 
       110        120        130        140        150
WSHDVFVPQT PEVVLSGDDE EYRRIYTTKI KPRLKSEDGV ETEAAGGTQS 
       160        170        180        190        200
RTITVTKRVT AYTVDVGGRE GARDLDLTSP EFKIKVPKHE LSHVSKAEFE 
       210        220        230        240        250
TEPGKIMTTT TTMTTTTIKI PQIDPVQGRP SEVTFAGPSV DSPSQRLEFG 
       260        270        280        290        300
VPDIRMEQSK VQISGPQISG PGLTITSPEI NGKMSGVSVD ISGPQIGGMK 
       310        320        330        340        350
APGSPGSLSF PAMKMPKFGI GSSALDVEVP QLDTSAPSVT IKGPDGSFKG 
       360        370        380        390        400
PKYTLGGSGD LHWKEGVKVA SPTLEGPKVD LKGPKVGFVE PDVGEGKIKL 
       410        420        430        440        450
PHMKLPKFSA SGPTVDASAP KGGIEISGPQ MDIQAPDVAL EAHVKGPKFG 
       460        470        480        490        500
HPEVVSQIPS ISMSDVDLSL KAPSLKGDMD ISVPKLEGGL KGPQVGIKGP 
       510        520        530        540        550
QVDVGIKGPS GQLKGLHIKA PQISIPDIDL NVKAPKVKGD LGVSVPKVEG 
       560        570        580        590        600
GLKGPVVDIK GPNVDLGAPS VDLHRPELKM PKMKLPKFGI QGEVPNVDVS 
       610        620        630        640        650
LPKGSVDISG PNVDVEAPTF GIKGPAGHLK GGPHVNVPEM HVKTPHITIP 
       660        670        680        690        700
DIDLNLQGPN LKGDVDVSLP KFEGGIKGPA VDLKGPEVDL GAPNVEFHGP 
       710        720        730        740        750
DFKMPKLKMP KFGMPGFKAE APDVEIGLPK GSVDISSPQL DIDAPNIGVK 
       760        770        780        790        800
GGQLKGPHVK MPQISIPDID LNLKAPKLKG DVDVSIPKVE GGLKGPTMDI 
       810        820        830        840        850
KGPKLDVGAP DVGLHGPELK MPKMKLPKFG VKGEVPDVDV TLPKGSIDIS 
       860        870        880        890        900
GPKVDVEAPT LGIKGPAGHL KGPHVKMPEM HVKTPHITIP DIDLNLQGPN 
       910        920        930        940        950
LKGDVDVSLP KVGGGLKGPA VDLKGPQVDF AAPDVDFHGP ELKMPKMKMP 
       960        970        980        990       1000
KFGIQGEVPD VDVGLPKGGL DISAPRVDLE GPELGFEGPE GKIKGHRFKM 
      1010       1020       1030       1040       1050
PEMPKISMPD IDLNLKGPRA KGGLDVSVPK VKGDFKGPRL DLEGPQLDVD 
      1060       1070       1080       1090       1100
VPDVELHGPE GKLKMPKMKM PKFGMPGFKG EAPDVDLSLP KGGINISGPK 
      1110       1120       1130       1140       1150
VDIDAPELEM EGPDVNIKGP KFRMPEMHMK TPKISMPDID LNLKRPKVKG 
      1160       1170       1180       1190       1200
EVDVSVPKLE GGLKSPEVDI KGPKLDVDIP DVDLQGPEGK LKMPKFKMPK 
      1210       1220       1230       1240       1250
FGMPSFKGEG PEVDVNLQRP DVDVSLPKVD VEGPSLDIEG PEGKLKGPKF 
      1260       1270       1280       1290       1300
RMPEMHIKAP KISMPDVDLN LKGPKWKGDV DISGPKVEGE LKGPSIDIKG 
      1310       1320       1330       1340       1350
PKLDVDVPDI DLEGPEAKLK MPKMKMPKFG IPGFRAEGPD VDVSLPKGEL 
      1360       1370       1380       1390       1400
DVDMPSVGVE GPEGKLKGPK FKMPEMHFKT PKISMPDVDL NLKGPKLKGD 
      1410       1420       1430       1440       1450
VDVSVPKLEG ELKGPNVDIK GPSVDFSAPD MDLQGEGKLK MPKLKMPHFS 
      1460       1470       1480       1490       1500
VSGPKLEGPD VDVNLPKGDL DFAGPKMDVE APDIDIEGPE GKLKGSRFKM 
      1510       1520       1530       1540       1550
PKLNIKAPKI SMPDVDLHLK GPGSRGEMDV TVPNLEADLK GPKVDLKAPD 
      1560       1570       1580       1590       1600
VSLEGPEGKL KGPKFKMPDM HFKTPHISMP DIDLNLKGPK LKGDVDVSLP 
      1610       1620       1630       1640       1650
KVEGPDVDIK GPKLDLDAPD VELHGPEGKL KMPKFKMPKF GMPGFRAEGP 
      1660       1670       1680       1690       1700
DVDVSLPKAD LEGDFEGPSL DIEGPEGKVK GPRFKMPEMH IKAPKISMPD 
      1710       1720       1730       1740       1750
VDFNLRGPKL KGDVDVSVPK LEGDLKGPNI DIEGPKLDID APAVDIEGPE 
      1760       1770       1780       1790       1800
GNWKTPKFKM PEMNIKAPKI SMPDVDFNLR GPKIKGDVDV SAPKLEGPDI 
      1810       1820       1830       1840       1850
DIKGPKLDID APDVDLHGPE GKVKGPKFRM PDMHFKTPKI SMPDIDLNLK 
      1860       1870       1880       1890       1900
GPKVKGDVDV SVPKLEGDLK GPNIDIHGPK LDVDVPDVEL EGPEGKLRGP 
      1910       1920       1930       1940       1950
KFKMPDMHFK APKISMPDVD FNLKGPKLKG DLDVSVPKLE GDLKGPDFDI 
      1960       1970       1980       1990       2000
KGPKLDIDAP DVDLHGPEGK LKMPKFKMPK FGMPSFKGEG PDVDLSLPKA 
      2010       2020       2030       2040       2050
DVDASLPKVD LEGPSLDVEG PEGKLKGPKF KMPDMHFKTP KISMPDIDLN 
      2060       2070       2080       2090       2100
LKGPKLKGDV DVSVPKVEGD LKGPDFNIKG PKLDVDLPDV DLEGPEGKLK 
      2110       2120       2130       2140       2150
GPKFKMPEMH IKAPKISMPD FDLSLKGPKV KGDVDVSIPK LEGDLKGPDV 
      2160       2170       2180       2190       2200
DLKGPKVDLD IPDVELEGPE GKWKAPKFKM PEMNIKAPKI SMPDFDLNLK 
      2210       2220       2230       2240       2250
GIDADIKGPQ LDIDVPDVSL EGPEGKVKGP KFKMPDMHFK TPKISMPDID 
      2260       2270       2280       2290       2300
LNLRGPKLKG DVDVSVPKLE GDLRGPDIDI KGPKLDIDAP DVEIEGPDGK 
      2310       2320       2330       2340       2350
WKGPKFKMPD MHFKTPKISM PDFDLNLKGP KVKGDVDVSV PKLEGDLKGP 
      2360       2370       2380       2390       2400
NIDIQGPKLD VDVPDVELEG PEGKLRGPKF KMPDMHFKAP KISMPDVDFN 
      2410       2420       2430       2440       2450
LKGPNWKGDV DVSLPKVEGP NIDLKGPKLD IDAPDVDLHG PEGKLKMPKF 
      2460       2470       2480       2490       2500
KMPKFGMPGF KGEGPEIDVN LPKGDIDVSA PKVDLEGPEL DIEGPEGKIK 
      2510       2520       2530       2540       2550
GPKFKMPEMH IKAPKISMPD VDFNLKGPKL KGDLDVSAPK LEGDLKGPDL 
      2560       2570       2580       2590       2600
DIKGPKVDID VPDVDLHGPE GKLKMPKFKM PKFGMPGFKG EGPEIDVSLP 
      2610       2620       2630       2640       2650
KGDIDVSAPK VDLEGPELDI EGPEGKIKGP KFKMPEMHIK APKISMPDVD 
      2660       2670       2680       2690       2700
FNLKGPKLKG DLDVSAPKLE GDLKGPDFDI KGPKVDIDVP DVDLHGPEGK 
      2710       2720       2730       2740       2750
LKMPKFKMPK FGMPGFKGEG PEIDVNLPKG DIDVSAPKVD LEGPELDIEG 
      2760       2770       2780       2790       2800
PEGKIKGPKF KMPEMHIKAP KISMPDVDFN LKGPKLKGDL DVSAPKLEGD 
      2810       2820       2830       2840       2850
LKGPDFDIKG PKVDIDVPDV DLHGPEGKLK MPKFKMPKFG MPGFKGEGPS 
      2860       2870       2880       2890       2900
VDVNLPKGEV DISAPKLDIE TPDLEIEGPE GKLKAPKFKK PDMHFNVPKI 
      2910       2920       2930       2940       2950
SMPDIDLNLR GPKIKGDVEG DIKGPNVELK GPDIDLEAPK IDIEAKPKKS 
      2960       2970       2980       2990       3000
RFKLPKFNFS GPKVHTPEVD VKLKKPDVDV SGPKLDVQGP DVDLQGKVKG 
      3010       3020       3030       3040       3050
SKFKMPSLNI SSPKVSVPDV ELNLKAPKLK GDLNVSSPSL EGDLKGPDID 
      3060       3070       3080       3090       3100
IKGPKLDIAA PDVDLHGPEA KLKMPKFKMP KFGMKGPEVD LNLPKADLDV 
      3110       3120       3130       3140       3150
TGPKMDIETP DLEIEGPEGK IKGSRFKMPD MNFEMPKISM PDIDLNLKGP 
      3160       3170       3180       3190       3200
KLKGGVDVSA PKLEGDLKGP DMDLKGPKLD ANLPDVEIEG PEGKLKGPKF 
      3210       3220       3230       3240       3250
KMPDLHFKAP KISMPDLDMN LKGPKLKGDV DVSVPKLEGD LKGPDVDIKG 
      3260       3270       3280       3290       3300
PKLDIDAPDV EIEGPDGKWK GPKFKMPDMH FKTPKISMPD IDLNLKGPKV 
      3310       3320       3330       3340       3350
KGDVDVSVPK LEGDLKGPNI DIQGPKLDVD VPDVELEGPE GKLRGPKFKM 
      3360       3370       3380       3390       3400
PELNIKAPKI SMPDVDFNLK GPKLKGDLDV SVPKLEGDLK GPDLDIKGPK 
      3410       3420       3430       3440       3450
LDIDAPDVDL HGPEGKLKMP KFKMPKFGMP SFKAEGPDVD VSLPKADLDV 
      3460       3470       3480       3490       3500
SLPKVDLEGP SLDVEGPEGK LKGPKFKMPD MHFKTPKISM PDIDLNLKGP 
      3510       3520       3530       3540       3550
KLKGDVDVSA PKLEGDLKGP DFDIKGPKLD IDAPDVEIEG PDGKWKGPKF 
      3560       3570       3580       3590       3600
KMPDMHFKTP KISMPDIDLN LKGPKVKGDV DVSVPKLEGD LKGPSVDIQG 
      3610       3620       3630       3640       3650
PKLDVDVPDV ELEGPDAKLR GPKFKMPEFN IKAPKISMPD VDFNLKGPKL 
      3660       3670       3680       3690       3700
KGDLDVSAPK FEGDLKGPEL DIKGPKLDID APDVDLHGPE GKLKMPKFKM 
      3710       3720       3730       3740       3750
PKFGMPGFKG EGPDVDVSLP KADLDVSLPK VDLEAPSLDV EGPEGKLKGP 
      3760       3770       3780       3790       3800
KFKMPDMHFK TPKISMPDFD LSLKGPKVKG DVDVSMPKLE GDFRGPDFDI 
      3810       3820       3830       3840       3850
KGPKLDVDVP DVELEGPDAK LRGPKFKMPE MNIKAPKISM PDVDFNLKGP 
      3860       3870       3880       3890       3900
KLKGDLDVSV PKLEGDLKGP DFDIKGPKLD IDAPDVDLHG PEGKLKMPKF 
      3910       3920       3930       3940       3950
KMPKFGMPGF KAEGPDVDVS LPKADLDVSL PKVDLEGPSL DVEGPEGKLK 
      3960       3970       3980       3990       4000
GPKFKMPDMH FKSPKISMPD MDFNLKGPKL KGDLDVSAPK FEGDLKGPDF 
      4010       4020       4030       4040       4050
DIKGPKVDID APDVDLHGPE GKLKMPKFKM PKFGMPGFKA EGPDVDVSLP 
      4060       4070       4080       4090       4100
KADLDVSLPK VDLEGPSLDV EGPEGKLKGP KFKMPDMHFK TPKFSMPDID 
      4110       4120       4130       4140       4150
LNLKGPKVKG DVDVSMPKLE GDFKGPDFDI KGPKLDVDVP DVDLEVPDPK 
      4160       4170       4180       4190       4200
LKGPKFKMPD MHFKTPKISM PDMNLNLKGP KVKGDMDVSV PKLEGDLKGP 
      4210       4220       4230       4240       4250
DVDIEGPDGK LKGPRFKMPE MNIKAPKISM PDMDFSLKGP KVKGDVDLDV 
      4260       4270       4280       4290       4300
SVPKIGGDLK GPDFDLKGPK VDVSVPDVDL ECPEGNLKGP KFKMPDMHFK 
      4310       4320       4330       4340       4350
TPKISMPDFD LNLKGPKVKG DVDVSAPKLE GPDFDIKGPK LDVDVPDVEL 
      4360       4370       4380       4390       4400
EGPDGKWKGP KFKMPEMHMK APKISMPDVD LNLKGPQMKG EGDFKGPEID 
      4410       4420       4430       4440       4450
IKGPKLDIDA PDVDLHGPKM KLPKMKLPKF GLSGFKGEGP DVDVNLPKGE 
      4460       4470       4480       4490       4500
LEFSGPKVNV EAPSLDVEGQ LKGPNVTMPE MHFKTPKISM PDIDLNLKGP 
      4510       4520       4530       4540       4550
KAKGDFNLKG PEMDLEGQGF GLKGPNIDLE CPDVNVEGPE GSVKLPKFKM 
      4560       4570       4580       4590       4600
PKFGFGAKSP KAEVKSPNLD VSLPEGDLSL ESPDVALSAK GKKSKFKMPK 
      4610       4620       4630       4640       4650
IHMSGPKIKG KKAGFDVSGE MDAGVKSPDL EGSISVPEAS LKGDLNVKSP 
      4660       4670       4680       4690       4700
KGKSVFGKLS FPDVEFDIKS PVFKADASLP KVEGDLKSPD LDITVPSLPD 
      4710       4720       4730       4740       4750
VNIGGPDVHM KKPKFHLSGG NVDLSGPKLE GDVQVPSFDA KLNAPDVNLK 
      4760       4770       4780       4790       4800
GPSVDIAAPS FSAPEVDLNL KGPKITGDVE VPHAELHGPE GKLKFPKFGK 
      4810       4820       4830       4840       4850
PGVKLDGPDV NLQGRSPSAS IDVSGLGGTG DLSFKGPKLG GDLGLSGDVK 
      4860       4870       4880       4890       4900
GPKVGFGGPE VNIGGFDGKF NLPKSPGLDV NVSAPDLDVK MSSSPDFDVN 
      4910       4920       4930       4940       4950
LKGPKVKGDL GFSGGISSPK FEGPQVNLEG GGGGGGVIRL PCMKLPQFGI 
      4960       4970       4980       4990       5000
SSEGDISGPG VDFQGPKLSA PDFDLNLKGP SLKGDVKVGT AGVKMPGMRF 
      5010       5020       5030       5040       5050
DAEAPDVSLR GPSLNVSAPK VSGPDFDVDV KGPKIKSPEF DGTGDLHVSG 
      5060       5070       5080       5090       5100
PKGGLGVKGP HGHLESPSGK VSFPKMKMPK FVVSGQEAAG REVGVDVEFP 
      5110       5120       5130       5140       5150
QATVLANVEL EEPDLKLKKS KIKMPKFAFS KPKAKGGEVS GGELKASLGS 
      5160       5170       5180       5190       5200
LEGDVEVGAE ASAASPKGKF SFFKTKKSRH RSSSFSDDHS SHSTPTGTLE 
      5210       5220       5230       5240       5250
HEGEKGKHGG AKLKFGTFGG IGSKNKGSYE VTGSDDEKTA SLASKKSRLS 
      5260       5270 
SSSSNDSGTK AGFRVPSVEL TVAKKKE
Length:5,277
Mass (Da):565,286
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9F5239B2538848F5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAWZ02034691 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000003553; ENSACAP00000003467; ENSACAG00000003562

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02034691 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000003467

Genome annotation databases

EnsembliENSACAT00000003553; ENSACAP00000003467; ENSACAG00000003562

Phylogenomic databases

eggNOGiENOG502QTQ3, Eukaryota
GeneTreeiENSGT00940000154902
HOGENOMiCLU_223458_0_0_1
InParanoidiH9G7Q6
OMAiPGPDMRG
TreeFamiTF344181

Gene expression databases

BgeeiENSACAG00000003562, Expressed in skeletal muscle tissue and 14 other tissues

Family and domain databases

Gene3Di2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR001478, PDZ
IPR036034, PDZ_sf
SMARTiView protein in SMART
SM00228, PDZ, 1 hit
SUPFAMiSSF50156, SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106, PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9G7Q6_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9G7Q6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 7, 2020
This is version 49 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again