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Entry version 43 (10 Feb 2021)
Sequence version 1 (16 May 2012)
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Protein
Submitted name:

RPGR interacting protein 1

Gene

RPGRIP1

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RPGR interacting protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPGRIP1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, CiliumARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000003174

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini593 – 730C2-C2_1InterPro annotationAdd BLAST138
Domaini1084 – 1247RPGR1_CInterPro annotationAdd BLAST164

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni438 – 459DisorderedSequence analysisAdd BLAST22
Regioni987 – 1013DisorderedSequence analysisAdd BLAST27

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili64 – 84Sequence analysisAdd BLAST21
Coiled coili102 – 136Sequence analysisAdd BLAST35
Coiled coili199 – 219Sequence analysisAdd BLAST21
Coiled coili299 – 329Sequence analysisAdd BLAST31
Coiled coili333 – 367Sequence analysisAdd BLAST35
Coiled coili406 – 426Sequence analysisAdd BLAST21
Coiled coili517 – 551Sequence analysisAdd BLAST35

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RPGRIP1 family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R3GU, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00520000055620

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002108_0_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
H9G798

Identification of Orthologs from Complete Genome Data

More...
OMAi
NTLAAGW

TreeFam database of animal gene trees

More...
TreeFami
TF328883

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021656, C2-C2_1
IPR035892, C2_domain_sf
IPR031134, RPGRIP1
IPR041091, RPGRIP1_C
IPR031139, RPGRIP1_fam

The PANTHER Classification System

More...
PANTHERi
PTHR14240, PTHR14240, 1 hit
PTHR14240:SF3, PTHR14240:SF3, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11618, C2-C2_1, 1 hit
PF18111, RPGR1_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9G798-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DETAGDLPVR DTNQKPSVIA AIQGQSWSRS LARTRRQIAR VTRTELEDGF
60 70 80 90 100
LRLHDENLLL KEFARKQEDR IKRMGTKLSR LSHERAQLDG RPGSWVRSTG
110 120 130 140 150
RNLDLEEDLE EMQERVRELE RHNEGLRNRL LFYKQQLQLQ GCGRHCPYSY
160 170 180 190 200
VTPRVNTGLR RANTAVGRVP ERLAKGMRMQ GPVARPTHTA PPRYGDHVLE
210 220 230 240 250
GSRAEMERLL KAFIEAKRNP LMDRKGRAID ITRVLKKIKT RLKLTLLIRK
260 270 280 290 300
EGILSDLKAA IQDNVELIRL QKLLRTKNSE LVLTKAQFAG LQENQDALRS
310 320 330 340 350
TSEALLAQVE ELNAHLKEET QKVTALESQL EILSPLQGTL KDFQERVQDL
360 370 380 390 400
ETERDLLKMD YDKLLERLDL CVFSCMTTAQ QNVDEVPQKD NAPCPEAQLI
410 420 430 440 450
LVTAEKKKLE EQLEKEIAHN EELKHEVSLL LTTAQEVGSP QEKSTIVENP
460 470 480 490 500
SREEEPHSHQ IQPLILEGEM EISMEKEEVF SQQSLNRKLH ETEAAHAETA
510 520 530 540 550
LELEKTRDML ILQHRINRDY QAELEGVLLQ ANREKQEREE KQENMAQLLD
560 570 580 590 600
LRSSRIRQLE EQLKDIAYGT RAVPFRMGEV DASLGTDPDK APQLRRGENL
610 620 630 640 650
FELHISGAVL SAEAQRFLGD AEPATFCTYS FYDFETHCTP VVRGIRPRYD
660 670 680 690 700
FTSQYVVRAE PFFLQYLQEA ACRLELHLAS AVDHATLASC RLRFGEALGT
710 720 730 740 750
GEQVHATAVL HGANGADYGL LEYWVRFRFP IEETLRLHHQ RTKALGYLSA
760 770 780 790 800
GVPRSTAVQL HWQKASTTKQ KSPASDTQGT NRNEVRVRIE GCAGLRSRWL
810 820 830 840 850
GSQPSPYAMY QFFTFPDHDT VIIPASNNPH FGDLQPFVVR VTPELHHYLL
860 870 880 890 900
VESLWVYVFD DEDEEPGNYL GKAQIPLLPL ANGRSISGDF VLLDPAGKPN
910 920 930 940 950
GSICLSLEWS LLYVPPEEAG VLKPTDLKPM EQQIETKQAR LRNQVISVGP
960 970 980 990 1000
RNNQNIICSS QPVSGQVLLE EIREEGEEIL ALEEEAAARN QRGSDAGSSM
1010 1020 1030 1040 1050
EAEAGMSKKP GIGCNQQGLE IKNMDRLTFL MSKQQGKPRK ETNWQQVENY
1060 1070 1080 1090 1100
ITSEEVESDA PTTESDEVVM ALSSLQEPLQ PEPSDRIRLE IISLSLLPES
1110 1120 1130 1140 1150
EPVADEHIQQ LYVEYHFPGV LLEETETPFS LRKPEGDQEI YFHFSKVIRL
1160 1170 1180 1190 1200
DPNPASLQRQ LLFSMLEAEE PEWNQLRFVV VSEPLPGAGG DCEEVGFAYL
1210 1220 1230 1240 1250
DLREILLTGC DVLERELWVV SSLDLETYVG KLKVSIEAAA VLRAVYWAGK

IKNTEC
Length:1,256
Mass (Da):142,569
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCC21D4E31749A107
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAWZ02028507 Genomic DNA No translation available.
AAWZ02028508 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000003255; ENSACAP00000003174; ENSACAG00000003274

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02028507 Genomic DNA No translation available.
AAWZ02028508 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000003174

Genome annotation databases

EnsembliENSACAT00000003255; ENSACAP00000003174; ENSACAG00000003274

Phylogenomic databases

eggNOGiENOG502R3GU, Eukaryota
GeneTreeiENSGT00520000055620
HOGENOMiCLU_002108_0_0_1
InParanoidiH9G798
OMAiNTLAAGW
TreeFamiTF328883

Family and domain databases

Gene3Di2.60.40.150, 3 hits
InterProiView protein in InterPro
IPR021656, C2-C2_1
IPR035892, C2_domain_sf
IPR031134, RPGRIP1
IPR041091, RPGRIP1_C
IPR031139, RPGRIP1_fam
PANTHERiPTHR14240, PTHR14240, 1 hit
PTHR14240:SF3, PTHR14240:SF3, 1 hit
PfamiView protein in Pfam
PF11618, C2-C2_1, 1 hit
PF18111, RPGR1_C, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9G798_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9G798
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: February 10, 2021
This is version 43 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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