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Entry version 47 (02 Jun 2021)
Sequence version 1 (16 May 2012)
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Protein
Submitted name:

Uncharacterized protein

Gene

gon4l

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gon4lImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000003005, Expressed in skeletal muscle tissue and 13 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000003132

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 40DisorderedSequence analysisAdd BLAST40
Regioni75 – 96DisorderedSequence analysisAdd BLAST22
Regioni672 – 701DisorderedSequence analysisAdd BLAST30
Regioni725 – 744DisorderedSequence analysisAdd BLAST20
Regioni757 – 978DisorderedSequence analysisAdd BLAST222
Regioni1185 – 1210DisorderedSequence analysisAdd BLAST26
Regioni1368 – 1429DisorderedSequence analysisAdd BLAST62
Regioni1448 – 1503DisorderedSequence analysisAdd BLAST56
Regioni1584 – 1613DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili105 – 125Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi11 – 38Acidic residuesSequence analysisAdd BLAST28
Compositional biasi761 – 787Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi793 – 816Polar residuesSequence analysisAdd BLAST24
Compositional biasi829 – 855Acidic residuesSequence analysisAdd BLAST27
Compositional biasi889 – 915Acidic residuesSequence analysisAdd BLAST27
Compositional biasi1190 – 1210Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi1410 – 1424Polar residuesSequence analysisAdd BLAST15
Compositional biasi1451 – 1467Polar residuesSequence analysisAdd BLAST17
Compositional biasi1476 – 1490Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1584 – 1605Basic and acidic residuesSequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QT2W, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164105

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000833_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H9G779

Identification of Orthologs from Complete Genome Data

More...
OMAi
LEDYRTD

TreeFam database of animal gene trees

More...
TreeFami
TF343327

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1160.11, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033277, GON-4-like
IPR009057, Homeobox-like_sf
IPR003822, PAH
IPR036600, PAH_sf

The PANTHER Classification System

More...
PANTHERi
PTHR16088:SF11, PTHR16088:SF11, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02671, PAH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 1 hit
SSF47762, SSF47762, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51477, PAH, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H9G779-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
WKQWLGSLMT DDMENEDEAD DDDDPEYNFL EDMDEPDTED FRNDRAVRIT
60 70 80 90 100
KKEVNELMEE LFETFQDEMG LSNVEDEGLE DEDSAAEARP NFNTPQVLRF
110 120 130 140 150
EEPLANLLNE QHRTVKEQLE QLRMKKSAAK TPQEAEKAKL RSEKPLQALA
160 170 180 190 200
LDAGQRKRLQ QQMQQHVQLL MQIYLLSSAN PSLSSEANTT RLLLTELDSF
210 220 230 240 250
AQSSTFLAQP LGHKFQTAFQ PCNLREALQL ITDFQSDVNI DWSPRKAIKK
260 270 280 290 300
NVNDFVPLPK PIAWILATRR VFMHPELLPT CSLKAKTPRD KIVFTKGEDN
310 320 330 340 350
LLALGLKHFE GTEFPKPLIS KYLLTTKTAH QLTVRIKNLN MNRVPDNILR
360 370 380 390 400
YYKTTKQLPV LSRLCEEVQP HDRKPPLEHD EHHLPFWLKA SLPSIQEELE
410 420 430 440 450
KMSREASVPG SELAGPGQGH KYPLRMPEGV QWMLRPLNSC LFRKTWRRQR
460 470 480 490 500
PAAAKPLPVR TGLCSPPAGG NNNFFKMAAR HPQPEAPPSK GSGRVPRLIQ
510 520 530 540 550
PAPFLQPLPV NLQPAPGNGA NFELQGLLPT RHPNLGAQNV IPALPVAFQP
560 570 580 590 600
KMMLPVLRVR KPGPTRGYQK KKAPLRAAPL LKPAPLLQPT PVIFTVPTAA
610 620 630 640 650
VNVVGIANGC NVLAATPASP QPIPITTLLV NPSPFPCPLN QPLAVPSAPP
660 670 680 690 700
LVVTSPMAST AVTVANVMAP GAGPNQAESQ EPSPCAAVSS KEHDALWSSD
710 720 730 740 750
ANTVAPVETS VEMMEENAGP IEKIQDDSSE AEPLPETPSS VGPLLNEDVV
760 770 780 790 800
LGLGQELDIE PPPRPAEEPK ESPRKQGSSE EGKGDLGAST ERTPSPCKDT
810 820 830 840 850
SSAPESVSSQ PKPEGGPSLP VSQEAGGEKD GPEEEEEEDF DDYIHDEEDE
860 870 880 890 900
EMSSASEESV LSVPELQETM EKLTWLASER RLSQEGDSEE ENSQEENSEP
910 920 930 940 950
EEEEEEEEEG ENLESLQKED EMTDEVADPA DRPALSLTLT CTVPEVEPRR
960 970 980 990 1000
SPPGENAKAP GKSRNSYRTR AKRGRSRASK DTSKLLLLYD EDILERDPLR
1010 1020 1030 1040 1050
EQKDLAFAQA YLSRVREALR SVPGKYEEFL RIIYEFESNA QKQTAVDLYA
1060 1070 1080 1090 1100
QLRSVLQGCP QLLTDFAAFL LPEQALECGL FEEQQAFEKS RKFLRQLEIC
1110 1120 1130 1140 1150
FAENPSHHQK IIKVLQSCAE CLPQEIVELK TQMWQLLKGH DHLQDEFSVF
1160 1170 1180 1190 1200
FDHLRPSASR LGDFEEINWT EEKEYEFDGF EEVSLPEVEE EEEPPKMHTA
1210 1220 1230 1240 1250
SKNKRRKELG GQNTDKELEW AEGAKECFCS CHEATGDLRM KRSKRRSCSH
1260 1270 1280 1290 1300
CSNKAAEGKL FKQKDTQELA DGLGPQEASL CPEGKDPVEE RLELREDGEL
1310 1320 1330 1340 1350
PLNRMRSAAR RADPSGAGLW GMKGCMRCFF FVCTPKAPTW LDKSGPNIME
1360 1370 1380 1390 1400
LRKEKGMRSM CSSVLFSPPF PGPRMEGKPP SCKDVPSEAK TPSEPCSVPD
1410 1420 1430 1440 1450
PPAATLATSA FSPKAPQPRS SPTGVGSEVG VALRSDEASS VLCRDISEPA
1460 1470 1480 1490 1500
THGATSPQNN KRTESDPVPS SRVLLRDTEM ENRPSSPETR ALRSKDTNGG
1510 1520 1530 1540 1550
LQAQRAAEAT VCAKNIKVSS TGEKVVLWTR EADRVILTTC QERGATPDTF
1560 1570 1580 1590 1600
GAISQRLCNK TADEVSHRFR ELMALFHTAC DVSSEDEDDG LSISHTDQLS
1610
DKDPVLSEEE QEE
Length:1,613
Mass (Da):179,259
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE9F59146FB97643B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAWZ02029580 Genomic DNA No translation available.
AAWZ02029581 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000003211; ENSACAP00000003132; ENSACAG00000003005

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02029580 Genomic DNA No translation available.
AAWZ02029581 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000003132

Genome annotation databases

EnsembliENSACAT00000003211; ENSACAP00000003132; ENSACAG00000003005

Phylogenomic databases

eggNOGiENOG502QT2W, Eukaryota
GeneTreeiENSGT00940000164105
HOGENOMiCLU_000833_0_0_1
InParanoidiH9G779
OMAiLEDYRTD
TreeFamiTF343327

Gene expression databases

BgeeiENSACAG00000003005, Expressed in skeletal muscle tissue and 13 other tissues

Family and domain databases

Gene3Di1.20.1160.11, 1 hit
InterProiView protein in InterPro
IPR033277, GON-4-like
IPR009057, Homeobox-like_sf
IPR003822, PAH
IPR036600, PAH_sf
PANTHERiPTHR16088:SF11, PTHR16088:SF11, 3 hits
PfamiView protein in Pfam
PF02671, PAH, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
SSF47762, SSF47762, 2 hits
PROSITEiView protein in PROSITE
PS51477, PAH, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH9G779_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H9G779
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: June 2, 2021
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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