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Protein

Sex-determining region Y protein

Gene

Sry

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi5 – 73HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorSAAS annotation, Calmodulin-bindingSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processDifferentiation, Sexual differentiationSAAS annotation, Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Sex-determining region Y proteinSAAS annotation
Gene namesi
Name:SryImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 73HMG boxInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili172 – 192Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the SRY family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0527 Eukaryota
ENOG410XT0K LUCA

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR017253 SRY
PANTHERiPTHR10270:SF199 PTHR10270:SF199, 1 hit
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

Sequencei

Sequence statusi: Fragment.

H8ZX76-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE
60 70 80 90 100
KRPFFQEAQR LKTLHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN
110 120 130 140 150
LLQWDRNPHA ITYRQDWSRA AHLYSKNQQS FYWQPVDIPT GHLQQQQQQQ
160 170 180 190 200
QQQQQQQFHN HHQQQQQFYD HHHQQQQQQQ QQQQQQQQQQ QQFHDHHQQK
210 220 230 240 250
QQFHDHHQQQ QQFHDHHHHH QQQQFHDHHQ QQQQFHDHQQ QQQQQQQQQF
260 270 280 290 300
HDHHQQKQQF HDHHHHQQQQ QFHDHQQQQQ QFHDHHQQQQ QFHDHQQQQH
310 320
QFHDHPQQKQ QFHDHPQQQQ Q
Length:321
Mass (Da):40,341
Last modified:May 16, 2012 - v1
Checksum:i39E9384E4F720A38
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei321Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN631121 Genomic DNA Translation: AFD96507.1
JN631145 Genomic DNA Translation: AFD96508.1
UniGeneiMm.377114

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN631121 Genomic DNA Translation: AFD96507.1
JN631145 Genomic DNA Translation: AFD96508.1
UniGeneiMm.377114

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0527 Eukaryota
ENOG410XT0K LUCA

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR017253 SRY
PANTHERiPTHR10270:SF199 PTHR10270:SF199, 1 hit
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH8ZX76_MOUSE
AccessioniPrimary (citable) accession number: H8ZX76
Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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